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Liqbiopsens

Reliable Novel Liquid Biopsy technology for early detection of colorectal cancer

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

Liqbiopsens project word cloud

Explore the words cloud of the Liqbiopsens project. It provides you a very rough idea of what is the project "Liqbiopsens" about.

interface wave flexibility validation false solution acoustic mutations zm delivering integration rates microelectronics technologies blood complementary microsensor transduction detection faster time reliability liqbiopsens technique free revolutionary label simultaneously min vary platform error thing awsensors nucleic quantitatively colorectal dgl direct cancer braf diagnostic inexpensive enabled samples multidisciplinary ctdna accurate copy multiplexing genomics destina sensitivity acids enzyme kras mentioned fast ltd resolution relies settings 27 property nanomaterials 95 positive microfluidics

Project "Liqbiopsens" data sheet

The following table provides information about the project.

Coordinator	ADVANCED WAVE SENSORS S.L. Organization address address: C/ CISCAR 40-8 city: VALENCIA postcode: 46005 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Spain [ES]
Project website	http://www.liqbiopsens.com
Total cost	2˙702˙268 €
EC max contribution	2˙307˙200 € (85%)
Programme	1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT))
Code Call	H2020-ICT-2015
Funding Scheme	IA
Starting year	2016
Duration (year-month-day)	from 2016-01-01 to 2018-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	ADVANCED WAVE SENSORS S.L. ADVANCED WAVE SENSORS S.L. Organization address address: C/ CISCAR 40-8 city: VALENCIA postcode: 46005 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (VALENCIA)	coordinator	415˙668.00
2	UNIVERSITE CATHOLIQUE DE LOUVAIN UNIVERSITE CATHOLIQUE DE LOUVAIN Organization address address: PLACE DE L UNIVERSITE 1 city: LOUVAIN LA NEUVE postcode: 1348 website: www.uclouvain.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (LOUVAIN LA NEUVE)	participant	501˙625.00
3	IDRYMA TECHNOLOGIAS KAI EREVNAS IDRYMA TECHNOLOGIAS KAI EREVNAS Organization address address: N PLASTIRA STR 100 city: IRAKLEIO postcode: 70013 website: www.forth.gr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (IRAKLEIO)	participant	450˙000.00
4	SERVICIO ANDALUZ DE SALUD SERVICIO ANDALUZ DE SALUD Organization address address: AVENIDA DE LA CONSTITUCION 18 city: SEVILLA postcode: 41071 website: http://www.sas.junta-andalucia.es/principal/default.asp contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (SEVILLA)	participant	433˙750.00
5	DESTINA GEONOMICS LTD DESTINA GEONOMICS LTD Organization address address: 7 11 MELVILLE STREET city: EDINBOURGH postcode: EH3 7JA website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (EDINBOURGH)	participant	386˙281.00
6	SISTEMAS GENOMICOS SL SISTEMAS GENOMICOS SL Organization address address: RONDA G MARCONI - PARQUE TECNOLOGICO DE VALENCIA 6 city: PATERNA postcode: 46980 website: www.sistemasgenomicos.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (PATERNA)	participant	119˙875.00
7	BEABLE SL BEABLE SL Organization address address: CALLE GENOVA 7 5 IZQ ESC INT 7 city: MADRID postcode: 28004 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (MADRID)	participant	0.00

Map

Project objective

The overall aim of LIQBIOPSENS project is the further development and validation in real settings of a novel diagnostic platform for the early and fast detection of ctDNA and their KRAS and BRAF mutations associated to colorectal cancer through blood samples. The main features of LIQBIOPSENS are: reliability (detection rates vary from 95–100 %), low-cost (40-50 € per sample analysis), sensitivity (in the zM range), multiplexing capabilities (analysis of 27 KRAS and BRAF mutations simultaneously), short analysis time (30-60 min.), user-friendly interface and flexibility. Solution proposed by the LIQBIOPSENS project relies on the multidisciplinary integration of different Key Enabled Technologies: microelectronics, microfluidics, nanomaterials and genomics. In particular, LIQBIOPSENS platform is based on the integration of two novel complementary technologies. On the one hand, the revolutionary DGL© technology property of DestiNA Genomics Ltd, capable of delivering faster, more error-free detection of nucleic acids and their mutations than current enzyme-based detection systems, making 'false positive' results a thing of the past. On the other hand, a novel high resolution acoustic wave microsensor technology property of AWSensors, that allows an accurate, inexpensive, label-free, direct and real time transduction method to quantitatively evaluate the results of the application of the above mentioned DGL© technique.

Deliverables

List of deliverables.
Project Website	Websites, patent fillings, videos etc.	2019-10-03 19:01:14
Multicriteria decision making mechanisms	Documents, reports	2019-10-03 19:01:14
Planning test phase report	Documents, reports	2019-10-03 19:01:14
9M technical & management Progress report	Documents, reports	2019-10-03 19:01:14
Periodic TF and Innovation evaluation Report 2	Documents, reports	2019-10-03 19:01:14
Technology Forecasting Plan	Documents, reports	2019-10-03 19:01:14
Periodic TF and Innovation evaluation Report 1	Documents, reports	2019-10-03 19:01:14
Dissemination Strategy	Documents, reports	2019-10-03 19:01:14
Project Intranet	Websites, patent fillings, videos etc.	2019-10-03 19:01:14
Risk Analysis & Management Plan	Documents, reports	2019-10-03 19:01:14
Project Handbook	Documents, reports	2019-10-03 19:01:14
18M technical & management Progress report	Documents, reports	2019-10-03 19:01:14
Periodical Dissemination Report 1	Documents, reports	2019-10-03 19:01:14
Periodic Report 1	Documents, reports	2019-10-03 19:01:14
Periodic TF and Innovation evaluation Report 3	Documents, reports	2019-10-03 19:01:14
Periodical Dissemination Report 2	Documents, reports	2019-10-03 19:01:14
Periodic TF and Innovation evaluation Report 4	Documents, reports	2019-10-03 19:01:14
Periodic TF and Innovation evaluation Report 5	Documents, reports	2019-10-03 19:01:14
Prototype of the platform	Demonstrators, pilots, prototypes	2019-10-03 19:01:14
Exploitation plan	Documents, reports	2019-10-03 19:01:14
Prototype of the platform - REPORT	Documents, reports	2019-10-03 19:01:14
Periodic Report 2	Documents, reports	2019-10-03 19:01:14
Operation manual of the LIQBIOPSENS system	Documents, reports	2019-10-03 19:01:14
Final Project Report	Documents, reports	2019-10-03 19:01:14
36M technical & management Progress report	Documents, reports	2019-10-03 19:01:14
27M technical & management Progress report	Documents, reports	2019-10-03 19:01:14
Continuous supply of disposable test cartridges to the rest of activities of LIQBIOPSENS project - REPORT	Documents, reports	2019-10-03 19:01:14
Periodical Dissemination Report 3	Documents, reports	2019-10-03 19:01:14
Control Software	Demonstrators, pilots, prototypes	2019-10-03 19:01:14
Validation Report	Documents, reports	2019-10-03 19:01:14
Control Software - REPORT	Documents, reports	2019-10-03 19:01:14

Take a look to the deliverables list in detail: detailed list of Liqbiopsens deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2018	Antonio Arnau, Hugh Ilyine Liqbiopsens â€“ Reliable Novel Liquid Biopsy technology for early detection of colorectal cancer â€“ H2020 published pages: 49-51, ISSN: 2398-7073, DOI: 10.21820/23987073.2018.12.49	Impact 2018/12	2019-10-03
2017	RomÃ¡n FernÃ¡ndez, Pablo GarcÃa, MarÃa GarcÃa, JosÃ© GarcÃa, Yolanda JimÃ©nez, Antonio Arnau Design and Validation of a 150 MHz HFFQCM Sensor for Bio-Sensing Applications published pages: 2057, ISSN: 1424-8220, DOI: 10.3390/s17092057	Sensors 17/9	2019-10-03
2017	Aristea Grammoustianou, George Papadakis, Electra Gizeli Solid-Phase Isothermal DNA Amplification and Detection on Quartz Crystal Microbalance Using Liposomes and Dissipation Monitoring published pages: 1-4, ISSN: 2475-1472, DOI: 10.1109/lsens.2017.2739803	IEEE Sensors Letters 1/5	2019-10-03

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The information about "LIQBIOPSENS" are provided by the European Opendata Portal: CORDIS opendata.