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MendoFold SIGNED

Linking mechanics and endoreduplication with tissue folding

Total Cost €

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EC-Contrib. €

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Partnership

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 MendoFold project word cloud

Explore the words cloud of the MendoFold project. It provides you a very rough idea of what is the project "MendoFold" about.

host    training    forms    lab    hypothesized    achievement    expertise    organisms    young    synergistically    slu    mechanisms    developmental    poorly    leader    meristem    opening    dna    decipher    writing    cell    aring    scientist    damage    enclosed    dr    soil    secondments    france    theoretical    hormonal    endoreduplication    yuan    receive    genomics    plan    signals    public    complementing    vib    protects    cutting    edge    communication    germination    msca    simultaneously    ghent    career    experimental    tissue    outstanding    force    plants    ens    vistas    mechanics    student    sweden    ume    immunocytochemistry    passes    apical    seedling    stem    shown    successful    embryonic    grant    ma    walls    plays    regulating    follow    lyon    interplay    hook    rigid    cytometry    engineering    microscopy    upsc    hypocotyl    belgium    researcher    deciphered    flow    cellular    survival    phd    biomechanics    seedlings    wall    fellowship    mentoring    techniques    elongation    ambition    division    differential    biology    goals    model    skills    plant    elucidation    engagement    atomic    cells    replication    biochemistry    critical    subsequent    personalized    shoot    environments    folding    gained   

Project "MendoFold" data sheet

The following table provides information about the project.

Coordinator
SVERIGES LANTBRUKSUNIVERSITET 

Organization address
address: ALMAS ALLE 8
city: UPPSALA
postcode: 750 07
website: http://www.slu.se

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Total cost 203˙852 €
 EC max contribution 203˙852 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-06-01   to  2022-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    SVERIGES LANTBRUKSUNIVERSITET SE (UPPSALA) coordinator 203˙852.00

Map

 Project objective

Tissue folding plays a key role in the development of all multi-cellular organisms. The aim of this MSCA-IF fellowship is to decipher the poorly understood mechanisms involved in regulating tissue folding in plants, using the apical hook as a model. The hook forms via tissue folding driven by differential cell elongation in the embryonic stem (hypocotyl) and is critical for the survival of young seedlings, since it protects the shoot apical meristem from damage as it passes through soil during seedling germination. Work in the host lab has recently shown that endoreduplication (DNA replication without subsequent cell division) is involved in hook development. Since plant cells are enclosed by rigid cell walls, it is hypothesized that tissue folding during apical hook formation involves an interplay between endoreduplication, cell wall mechanics and hormonal signals which will be deciphered by Dr. Yuan Ma during this fellowship. Simultaneously, Dr. Ma will receive training in cutting- edge techniques like atomic force microscopy, flow cytometry, and immunocytochemistry in leading environments such the host lab at SLU/UPSC (Umeå, Sweden) and via secondments to VIB (Ghent, Belgium) and ENS (Lyon, France). Synergistically complementing skills in biochemistry and genomics gained during his PhD, this training will provide Dr. Ma with a unique technical and theoretical expertise in experimental biomechanics, strongly promoting a successful achievement of the project’s goals, opening of new vistas in developmental biomechanics, and support the researcher’s ambition of becoming a research leader. The researcher will follow a personalized career development plan, to also enhance skills such as communication, grant writing, public engagement and student mentoring. Thus, this MSCA-IF will enable elucidation of a key process in developmental systems biology (with important applications in tissue engineering), and career advancement of a scientist with outstanding potential.

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The information about "MENDOFOLD" are provided by the European Opendata Portal: CORDIS opendata.

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