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MendoFold SIGNED

Linking mechanics and endoreduplication with tissue folding

Total Cost €

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EC-Contrib. €

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Partnership

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 MendoFold project word cloud

Explore the words cloud of the MendoFold project. It provides you a very rough idea of what is the project "MendoFold" about.

msca    tissue    cellular    rigid    decipher    developmental    hormonal    engagement    elongation    organisms    biology    meristem    vib    biochemistry    opening    shoot    gained    plan    career    cell    microscopy    follow    hypocotyl    apical    division    mechanisms    forms    germination    replication    theoretical    scientist    cytometry    stem    goals    genomics    differential    phd    complementing    plant    dna    slu    force    shown    synergistically    writing    training    vistas    student    mentoring    plants    embryonic    fellowship    receive    wall    deciphered    successful    immunocytochemistry    soil    hook    hypothesized    achievement    skills    france    expertise    personalized    enclosed    ume    lab    seedlings    leader    ens    engineering    subsequent    ma    folding    regulating    public    survival    upsc    ghent    techniques    walls    cells    poorly    protects    biomechanics    sweden    passes    plays    yuan    elucidation    experimental    signals    host    endoreduplication    edge    model    researcher    cutting    seedling    aring    communication    mechanics    secondments    critical    dr    interplay    outstanding    belgium    atomic    ambition    damage    environments    simultaneously    young    grant    flow    lyon   

Project "MendoFold" data sheet

The following table provides information about the project.

Coordinator
SVERIGES LANTBRUKSUNIVERSITET 

Organization address
address: ALMAS ALLE 8
city: UPPSALA
postcode: 750 07
website: http://www.slu.se

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Total cost 203˙852 €
 EC max contribution 203˙852 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-06-01   to  2022-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    SVERIGES LANTBRUKSUNIVERSITET SE (UPPSALA) coordinator 203˙852.00

Map

 Project objective

Tissue folding plays a key role in the development of all multi-cellular organisms. The aim of this MSCA-IF fellowship is to decipher the poorly understood mechanisms involved in regulating tissue folding in plants, using the apical hook as a model. The hook forms via tissue folding driven by differential cell elongation in the embryonic stem (hypocotyl) and is critical for the survival of young seedlings, since it protects the shoot apical meristem from damage as it passes through soil during seedling germination. Work in the host lab has recently shown that endoreduplication (DNA replication without subsequent cell division) is involved in hook development. Since plant cells are enclosed by rigid cell walls, it is hypothesized that tissue folding during apical hook formation involves an interplay between endoreduplication, cell wall mechanics and hormonal signals which will be deciphered by Dr. Yuan Ma during this fellowship. Simultaneously, Dr. Ma will receive training in cutting- edge techniques like atomic force microscopy, flow cytometry, and immunocytochemistry in leading environments such the host lab at SLU/UPSC (Umeå, Sweden) and via secondments to VIB (Ghent, Belgium) and ENS (Lyon, France). Synergistically complementing skills in biochemistry and genomics gained during his PhD, this training will provide Dr. Ma with a unique technical and theoretical expertise in experimental biomechanics, strongly promoting a successful achievement of the project’s goals, opening of new vistas in developmental biomechanics, and support the researcher’s ambition of becoming a research leader. The researcher will follow a personalized career development plan, to also enhance skills such as communication, grant writing, public engagement and student mentoring. Thus, this MSCA-IF will enable elucidation of a key process in developmental systems biology (with important applications in tissue engineering), and career advancement of a scientist with outstanding potential.

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The information about "MENDOFOLD" are provided by the European Opendata Portal: CORDIS opendata.

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