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MATBFOB SIGNED
MAThematical modelling of Biofilm FOrmation on Biomaterials
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0MATBFOB project word cloud
Explore the words cloud of the MATBFOB project. It provides you a very rough idea of what is the project "MATBFOB" about.
mass
biofilms
manufacturers
scientists
structures
deciphering
manner
observations
surfaces
fundamental
simulate
microbiologists
treatment
visualising
nutrient
consists
microbes
colonies
mathematical
detachment
aeruginosa
urinary
biomaterial
infections
experimental
monitoring
tool
vascular
bacterial
stages
acknowledged
considering
little
modellers
interaction
microbe
spread
substrate
cardiac
guided
mathematically
biofilm
interactions
pathogen
pivotal
time
indwelling
spatio
healthcare
wastewater
endeavour
brand
transfer
pseudomonas
catheters
progression
model
implants
pacemakers
models
surgeons
originate
characterizing
dynamics
play
surface
microbial
tools
suitable
precise
gradual
effect
establishment
morphology
medical
rate
forces
implant
of
biomaterials
initiation
elucidate
temporal
exact
nosocomial
orthopaedic
brief
adhesion
correlate
couple
employ
Project "MATBFOB" data sheet
The following table provides information about the project.
| Coordinator |
THE UNIVERSITY OF EXETER
Organization address contact info |
| Coordinator Country | United Kingdom [UK] |
| Total cost | 337˙400 € |
| EC max contribution | 337˙400 € (100%) |
| Programme |
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility) |
| Code Call | H2020-MSCA-IF-2019 |
| Funding Scheme | MSCA-IF-EF-CAR |
| Starting year | 2020 |
| Duration (year-month-day) | from 2020-06-01 to 2023-05-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | THE UNIVERSITY OF EXETER | UK (EXETER) | coordinator | 337˙400.00 |
Map
Project objective
Biofilms play a pivotal role in healthcare-associated infections, especially those related to indwelling medical devices, such as intra-vascular and urinary catheters, cardiac pacemakers and orthopaedic implants. Many mathematical models have been developed to simulate and elucidate the main processes characterizing biofilm growth. Biofilm models have been widely acknowledged as a tool for fundamental understanding of wastewater treatment processes, the morphology of biofilm structures and for deciphering the manner in which they originate through the interaction of a couple of factors like: mass transfer, nutrient availability, detachment forces etc. However there has been very little or no endeavour to develop a suitable model for understanding the exact stages of microbial adhesion on biomaterials and the process of gradual establishment of microbial colonies on medical devices, considering the effect of substrate-microbe interactions . The proposed project consists of a brief and precise experimental part for investigating the initiation and progression of biofilm formation of Pseudomonas aeruginosa, a nosocomial pathogen, on implant surfaces through real-time monitoring. The experimental observations will be used to mathematically model the process of growth of biofilm on a biomaterial surface, considering the effect of interactions of microbes with a specific substrate and the rate of nutrient uptake.The project will employ currently used mathematical tools to model the spatio-temporal dynamics of biofilm formation of Pseudomonas aeruginosa on different biomaterial surfaces.The model will help in visualising the manner and the rate at which bacterial infections can spread on a particular surface and correlate it with the surface properties. This will be the initiation of - model guided substrate design of implants- a brand new concept for implant manufacturers, orthopaedic surgeons, biomaterial scientists, microbiologists and biofilm modellers.
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The information about "MATBFOB" are provided by the European Opendata Portal: CORDIS opendata.
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