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EPIGEN: A New Predictive Response Test for Non Small Cells Lung Cancer Treatment

Total Cost €


EC-Contrib. €






Project "EPIGEN" data sheet

The following table provides information about the project.


Organization address
city: MADRID
postcode: 28002

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-1-2015
 Funding Scheme SME-1
 Starting year 2015
 Duration (year-month-day) from 2015-09-01   to  2015-10-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    IGEN BIOTECH SL ES (MADRID) coordinator 50˙000.00


 Project objective

EPIGEN test is a ready-to-use tool capable to lead the oncologist to the best Non Smal Cell Lung Cancer treatment, the most common subtype of lung cancer (80% of cases). The standar treatments to combat NSCLC are both chemo- and radiotherapy, but many patients (up to 65%) presents resistance, and currently there is not any tool available for the clinician to predict it. The EPIGEN test will allow the clinician a patient stratification in terms of the patient susceptibility to radio- and chemotherapy, and therefore lead for a personalyzed prescription. The EPIGEN test tecnology is based on the determination of the methylation percentage of the epigenetic biomarker IGFBP-3 in the patient tumor samples. The methylation percentage of IGFBP-3 is determined by using qMS-PCR (quantitative methylation specific polymerase chain) tecnique, a well known and extended biochemistry tecnique. The methylation percentage provided by using the EPIGEN test protocol and reagents in the qMS-PCR tecnique will lead the clinician for the optimal NSCLC treatment, avoiding the possible patient resistance to chemo and radiotharapy, and therefore unnecesary side effects and costly therapies.

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The information about "EPIGEN" are provided by the European Opendata Portal: CORDIS opendata.

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