MSmed project deliverables
The page lists 10 deliverables related to the research project "MSmed".
List of Deliverables
| title and desprition | type | last update |
|---|---|---|
LCMS time-scale compatible peptide and protein sequencing using hybrid fragmentation methods, with special applications into multiply modified larger peptidesBenchmark the performance in peptide and protein identifications of EThcD versus HCD peptides from complex mixtures, whereby the Mw of the peptides is in the range between 2.5 and 10 kDa (middle-down proteomics) Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2019-05-03 |
Construction/coupling of UVPD to the latest Orbitrap instrumentsAn UVPD laser will be coupled to the latest Q-Exactive mass analyzer and/or other Orbitrap instruments Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2019-05-03 |
Software module for comprehensive identification of PTMs, mutations and splice variantsImplement genome-informed proteomics platform that incorporates knowledge on human natural variations, disease mutations and alternative splicing. Ensure efficiency of search algorithm in huge protein/peptide spaces further inflated by multiple PTMs. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2019-05-03 |
MaxQuant summer schoolThe annual MaxQuant Summer School (host: MPIB, over 160 participants) provides an introduction into the MaxQuant software and application examples. Projeect results will be included into the School’s curriculum. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Other | 2019-05-03 |
Industrialized workflow with low CVsDevelop and test a workflow that enables robust analysis of hundreds of tissue and body fluid samples with minimal intervention and CVs in the smaller than 20% range for proteins of interest Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2019-05-03 |
Software module for multiplexed quantification of clinical samplesDevelop and test software module that enables low variance quantification in body fluid and tissue samples for MS1 and MS2 label and label free quantification for hundreds of patients simultaneously. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2019-05-07 |
LCMS time-scale compatible UV-PD peptide and protein sequencingBenchmark the performance in peptide and protein identifications of UVPD versus HCD using a cellular lysate on a Q-Exactive instrument (bottom-up proteomics) Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2019-05-07 |
Robust and reproducible sample prepa¬ration protocols including MS instru¬mentation and acquisition strat-egies for large-scale, quantitative PTM analysis from primary tissue samples such as patient biopsy materialEstablish tissue sample preparation protocol based on heat-inactivation of biopsies, efficient protein extraction by ceramic bead milling, in-solution digestion and optimized nanoflow LC-MS/MS acquisition strategies. Benchmark the performance versus established protocols. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Other | 2019-05-07 |
Ethics checkAll relevant ethical approvals, consent forms and patient information sheets will be uploaded as deliverable 6.12. This will also include an up to date approval from The Central Denmark Region Committees on Health Research Ethics stating the ethical approvals for Aarhus University Hospital are also valid for project MSmed. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2019-05-07 |
Data Management PlanDescribes the strategy for depositing and curating MSmed experimental data in publicly accessible proteomic data bases, the use of proteomic standard formats, and exceptions made as required to protect personal data and intellectual property to be patented Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Other | 2019-05-07 |