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Mass spectrometric technology for next generation proteomics in systems medicine

Total Cost €


EC-Contrib. €






 MSmed project word cloud

Explore the words cloud of the MSmed project. It provides you a very rough idea of what is the project "MSmed" about.

omic    track    drug    modifications    generation    leaders    breakthroughs    larger    expression    vision    academia    clinic    ready    quantify    mechanisms    multiplexed    applicants    contexts    performance    eco    identification    protein    diagnosis    routinely    representative    myriad    generate    bling    mined    turn    mentation    health    disease    frag    pioneering    clinical    sequencing    improvement    industrial    mass    strength    spectrometry    data    ena    automated    spectrometric    enrichment    global    breakthrough    patient    record    organoids    fluids    proteome    community    industry    basis    tissues    merged    laboratory    instrumentation    platforms    isoforms    not    biomedicine    proteins    tionize    systems    throughput    multidimensional    workflow    biological    revolu    area    medicine    oriented    machine    genomic    separation    designates    biologically    profiling    human    ten    workflows    urgent    powerful    elucidations    advancing    levels    body    learning    cells    proteomics    made    prognosis    gene    technologies    action   

Project "MSmed" data sheet

The following table provides information about the project.


Organization address
address: NORREGADE 10
postcode: 1165

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Denmark [DK]
 Project website http://www.nowebsite.none
 Total cost 5˙038˙875 €
 EC max contribution 3˙672˙625 € (73%)
 Programme 1. H2020-EU.1.2.1. (FET Open)
 Code Call H2020-FETOPEN-2014-2015-RIA
 Funding Scheme RIA
 Starting year 2015
 Duration (year-month-day) from 2015-12-01   to  2019-11-30


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) coordinator 1˙403˙600.00
3    UNIVERSITEIT UTRECHT NL (UTRECHT) participant 700˙000.00


 Project objective

Systems medicine designates the application of global approaches to human health and disease. Genomic technologies, especially next-generation sequencing, are already pioneering this new area. There is an urgent need to advance proteomics technologies to a similar level. This will help revolu¬tionize diagnosis and prognosis based on the expression levels and modifications of proteins in cells, tissues, organoids or body fluids. Our vision is to make mass spectrometry so robust and powerful that it will be present in every biological laboratory and in every clinic. The applicants are leaders in proteomics technologies from academia and industry and have an out-standing track-record in advancing both instrumentation as well as its application in biological and disease contexts. Here we come together to develop breakthrough technology capable of more than a factor ten improvement in parameters of performance of the mass spectrometric workflow, ena¬bling patient-oriented proteome profiling. The proteomics workflow will be automated, multiplexed and made ‘industrial strength’ - ready for high-throughput and in-depth clinical applications. Importantly, in addition to the identification of the main protein representative of a gene, we aim to routinely identify and quantify protein modifications and isoforms by using multidimensional approaches, including new separation, enrichment and frag¬mentation technologies. The breakthroughs aimed for will generate larger more biologically relevant data. This data will be merged with other ‘omic’ data and mined using machine learning technologies. Our results will establish the role mass spectrometry in systems medicine, making all workflows and mass spectrometry platforms available to the community. They will be used as the basis of myriad applications in biomedicine, even in the clinic. This in turn will lead to a new eco-system around improved diagnosis, elucidations of disease mechanisms and drug action.


List of deliverables.
LCMS time-scale compatible peptide and protein sequencing using hybrid fragmentation methods, with special applications into multiply modified larger peptides Documents, reports 2019-05-03 16:53:16
Construction/coupling of UVPD to the latest Orbitrap instruments Documents, reports 2019-05-03 16:53:42
Software module for comprehensive identification of PTMs, mutations and splice variants Documents, reports 2019-05-03 16:44:40
MaxQuant summer school Other 2019-05-03 16:44:41
Industrialized workflow with low CVs Documents, reports 2019-05-03 16:44:39
Software module for multiplexed quantification of clinical samples Documents, reports 2019-05-07 11:36:07
LCMS time-scale compatible UV-PD peptide and protein sequencing Documents, reports 2019-05-07 11:36:08
Robust and reproducible sample prepa¬ration protocols including MS instru¬mentation and acquisition strat-egies for large-scale, quantitative PTM analysis from primary tissue samples such as patient biopsy material Other 2019-05-07 11:36:04
Ethics check Documents, reports 2019-05-07 11:36:02
Data Management Plan Other 2019-05-07 11:36:02

Take a look to the deliverables list in detail:  detailed list of MSmed deliverables.


year authors and title journal last update
List of publications.
2019 Clement M. Potel, Miao-Hsia Lin, Nadine Prust, Henk W. P. van den Toorn, Albert J. R. Heck, Simone Lemeer
Gaining Confidence in the Elusive Histidine Phosphoproteome
published pages: 5542-5547, ISSN: 0003-2700, DOI: 10.1021/acs.analchem.9b00734
Analytical Chemistry 91/9 2020-01-30
2019 Jean-François Greisch, Sem Tamara, Richard A. Scheltema, Howard W. R. Maxwell, Robert D. Fagerlund, Peter C. Fineran, Stephan Tetter, Donald Hilvert, Albert J. R. Heck
Expanding the mass range for UVPD-based native top-down mass spectrometry
published pages: 7163-7171, ISSN: 2041-6520, DOI: 10.1039/c9sc01857c
Chemical Science 10/30 2020-01-30
2019 Marta Murgia, Jing Tan, Philipp E. Geyer, Sophia Doll, Matthias Mann, Thomas Klopstock
Proteomics of Cytochrome c Oxidase-Negative versus -Positive Muscle Fiber Sections in Mitochondrial Myopathy
published pages: 3825-3834.e4, ISSN: 2211-1247, DOI: 10.1016/j.celrep.2019.11.055
Cell Reports 29/12 2020-01-29
2018 Miao-Hsia Lin, Clement M. Potel, Kamaleddin H. M. E. Tehrani, Albert J. R. Heck, Nathaniel I. Martin, Simone Lemeer
A New Tool to Reveal Bacterial Signaling Mechanisms in Antibiotic Treatment and Resistance
published pages: 2496-2507, ISSN: 1535-9476, DOI: 10.1074/mcp.ra118.000880
Molecular & Cellular Proteomics 17/12 2020-01-29
2018 Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
published pages: 2018-2033, ISSN: 1535-9476, DOI: 10.1074/mcp.ra118.000924
Molecular & Cellular Proteomics 17/10 2020-01-30
2018 Oleg Klykov, Barbara Steigenberger, Sibel PektaÅŸ, Domenico Fasci, Albert J. R. Heck, Richard A. Scheltema
Efficient and robust proteome-wide approaches for cross-linking mass spectrometry
published pages: 2964-2990, ISSN: 1754-2189, DOI: 10.1038/s41596-018-0074-x
Nature Protocols 13/12 2020-01-30
2019 Tomislav ÄŒaval, Jing Zhu, Albert J.R. Heck
Simply Extending the Mass Range in Electron Transfer Higher Energy Collisional Dissociation Increases Confidence in N-Glycopeptide Identification
published pages: 10401-10406, ISSN: 0003-2700, DOI: 10.1021/acs.analchem.9b02125
Analytical Chemistry 91/16 2020-01-30
2019 Laura C. Demmers, Albert J. R. Heck, Wei Wu
Pre-fractionation Extends but also Creates a Bias in the Detectable HLA Class Ι Ligandome
published pages: 1634-1643, ISSN: 1535-3893, DOI: 10.1021/acs.jproteome.8b00821
Journal of Proteome Research 18/4 2020-01-30
2018 Karli R. Reiding, Albert Bondt, Vojtech Franc, Albert J.R. Heck
The benefits of hybrid fragmentation methods for glycoproteomics
published pages: 260-268, ISSN: 0165-9936, DOI: 10.1016/j.trac.2018.09.007
TrAC Trends in Analytical Chemistry 108 2020-01-29
2018 David Y. Chiang, Katherina M. Alsina, Eleonora Corradini, Martin Fitzpatrick, Li Ni, Satadru K. Lahiri, Julia O. Reynolds, Xiaolu Pan, Larry Scott, Albert J.R. Heck, Xander H.T. Wehrens
Rearrangement of the Protein Phosphatase 1 Interactome During Heart Failure Progression
published pages: 1569-1581, ISSN: 0009-7322, DOI: 10.1161/circulationaha.118.034361
Circulation 138/15 2020-01-29
2018 Kristina B. Emdal, Anna-Kathrine Pedersen, Dorte B. Bekker-Jensen, Alicia Lundby, Shana Claeys, Katleen De Preter, Frank Speleman, Chiara Francavilla, Jesper V. Olsen
Integrated proximal proteomics reveals IRS2 as a determinant of cell survival in ALK-driven neuroblastoma
published pages: eaap9752, ISSN: 1937-9145, DOI: 10.1126/scisignal.aap9752
Science Signaling 11/557 2020-01-30
2018 Jing Zhu, Luc Garrigues, Henk Van den Toorn, Bernd Stahl, Albert J. R. Heck
Discovery and Quantification of Nonhuman Proteins in Human Milk
published pages: 225-238, ISSN: 1535-3893, DOI: 10.1021/acs.jproteome.8b00550
Journal of Proteome Research 18/1 2020-01-30
2019 Tanveer S. Batth, Maxim A. X. Tollenaere, Patrick Rüther, Alba Gonzalez-Franquesa, Bhargav S. Prabhakar, Simon Bekker-Jensen, Atul S. Deshmukh, Jesper V. Olsen
Protein Aggregation Capture on Microparticles Enables Multipurpose Proteomics Sample Preparation
published pages: 1027-1035, ISSN: 1535-9476, DOI: 10.1074/mcp.tir118.001270
Molecular & Cellular Proteomics 18/5 2020-01-30
2018 Clement M Potel, Miao-Hsia Lin, Albert J R Heck, Simone Lemeer
Widespread bacterial protein histidine phosphorylation revealed by mass spectrometry-based proteomics
published pages: 187-190, ISSN: 1548-7091, DOI: 10.1038/nmeth.4580
Nature Methods 15/3 2020-01-30
2019 Hecht, E.S., Scigelova, M., Eliuk, S. and Makarov, A.
Fundamentals and Advances of Orbitrap Mass Spectrometry
published pages: , ISSN: , DOI:
Encyclopedia of Analytical Chemistry 2020-01-29
2018 Sebastiaan C. de Graaf, Oleg Klykov, Henk van den Toorn, Richard A. Scheltema
Cross-ID: Analysis and Visualization of Complex XL–MS-Driven Protein Interaction Networks
published pages: 642-651, ISSN: 1535-3893, DOI: 10.1021/acs.jproteome.8b00725
Journal of Proteome Research 18/2 2020-01-30
2019 Dorte B. Bekker-Jensen, Oliver M. Bernhardt, Alexander Hogrebe, Ana Martinez del Val, Lynn Verbeke, Tejas Gandhi, Christian D. Kelstrup, Lukas Reiter, Jesper V. Olsen
Rapid and site-specific deep phosphoproteome profiling by data-independent acquisition (DIA) without the need for spectral libraries
published pages: , ISSN: , DOI: 10.1101/657858
bioRxiv 2020-01-30
2019 Dorte B. Bekker-Jensen, Ana Martínez del Val, Sophia Steigerwald, Patrick Rüther, Kyle Fort, Tabiwang N. Arrey, Alexander Harder, Alexander Makarov, Jesper V. Olsen
A Compact Quadrupole-Orbitrap Mass Spectrometer with FAIMS Interface Improves Proteome Coverage in Short LC Gradients
published pages: , ISSN: , DOI: 10.1101/860643
bioRxiv 2020-01-30
2018 Clement M. Potel, Simone Lemeer, Albert J. R. Heck
Phosphopeptide Fragmentation and Site Localization by Mass Spectrometry: An Update
published pages: 126-141, ISSN: 0003-2700, DOI: 10.1021/acs.analchem.8b04746
Analytical Chemistry 91/1 2020-01-30
2019 Kelly A. Dingess, Henk W. P. van den Toorn, Marko Mank, Bernd Stahl, Albert J. R. Heck
Toward an efficient workflow for the analysis of the human milk peptidome
published pages: 1351-1363, ISSN: 1618-2642, DOI: 10.1007/s00216-018-01566-4
Analytical and Bioanalytical Chemistry 411/7 2020-01-30
2018 Vyacheslav Akimov, Inigo Barrio-Hernandez, Sten V. F. Hansen, Philip Hallenborg, Anna-Kathrine Pedersen, Dorte B. Bekker-Jensen, Michele Puglia, Stine D. K. Christensen, Jens T. Vanselow, Mogens M. Nielsen, Irina Kratchmarova, Christian D. Kelstrup, Jesper V. Olsen, Blagoy Blagoev
UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites
published pages: 631-640, ISSN: 1545-9993, DOI: 10.1038/s41594-018-0084-y
Nature Structural & Molecular Biology 25/7 2020-01-30
2019 Tomislav ÄŒaval, Jing Zhu, Weihua Tian, Sanne Remmelzwaal, Zhang Yang, Henrik Clausen, Albert J.R. Heck
Targeted Analysis of Lysosomal Directed Proteins and Their Sites of Mannose-6-phosphate Modification
published pages: 16-27, ISSN: 1535-9476, DOI: 10.1074/mcp.ra118.000967
Molecular & Cellular Proteomics 18/1 2020-01-30
2018 Clement M. Potel, Domenico Fasci, Albert J.R. Heck
Mix and match of the tumor metastasis suppressor Nm23 protein isoforms in vitro and in vivo
published pages: 2856-2868, ISSN: 1742-464X, DOI: 10.1111/febs.14525
The FEBS Journal 285/15 2020-01-29
2019 Christoph Wichmann, Florian Meier, Sebastian Virreira Winter, Andreas-David Brunner, Jürgen Cox, Matthias Mann
MaxQuant.Live Enables Global Targeting of More Than 25,000 Peptides
published pages: 982-994, ISSN: 1535-9476, DOI: 10.1074/mcp.tir118.001131
Molecular & Cellular Proteomics 18/5 2020-01-30
2019 Barbara Steigenberger, Roland J. Pieters, Albert J. R. Heck, Richard A. Scheltema
PhoX: An IMAC-Enrichable Cross-Linking Reagent
published pages: 1514-1522, ISSN: 2374-7943, DOI: 10.1021/acscentsci.9b00416
ACS Central Science 5/9 2020-01-30
2017 Miia R. Mäkelä, Ourdia Bouzid, Diogo Robl, Harm Post, Mao Peng, Albert Heck, Maarten Altelaar, Ronald P. de Vries
Cultivation of Podospora anserina on soybean hulls results in an efficient enzyme cocktail for plant biomass hydrolysis
published pages: 162-171, ISSN: 1871-6784, DOI: 10.1016/j.nbt.2017.02.002
New Biotechnology 37 2020-01-30
2019 Philipp E Geyer, Eugenia Voytik, Peter V Treit, Sophia Doll, Alisa Kleinhempel, Lili Niu, Johannes B Müller, Marie‐Luise Buchholtz, Jakob M Bader, Daniel Teupser, Lesca M Holdt, Matthias Mann
Plasma Proteome Profiling to detect and avoid sample‐related biases in biomarker studies
published pages: e10427, ISSN: 1757-4676, DOI: 10.15252/emmm.201910427
EMBO Molecular Medicine 11/11 2020-01-30
2019 Andrey Dyachenko, Sem Tamara, Albert J. R. Heck
Distinct Stabilities of the Structurally Homologous Heptameric Co-Chaperonins GroES and gp31
published pages: 7-15, ISSN: 1044-0305, DOI: 10.1007/s13361-018-1910-5
Journal of The American Society for Mass Spectrometry 30/1 2020-01-30
2019 Alicia Lundby, Giulia Franciosa, Kristina B. Emdal, Jan C. Refsgaard, Sebastian P. Gnosa, Dorte B. Bekker-Jensen, Anna Secher, Svetlana R. Maurya, Indranil Paul, Blanca L. Mendez, Christian D. Kelstrup, Chiara Francavilla, Marie Kveiborg, Guillermo Montoya, Lars J. Jensen, Jesper V. Olsen
Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
published pages: 543-560.e26, ISSN: 0092-8674, DOI: 10.1016/j.cell.2019.09.008
Cell 179/2 2020-01-30
2019 Lili Niu, Philipp E Geyer, Nicolai J Wewer Albrechtsen, Lise L Gluud, Alberto Santos, Sophia Doll, Peter V Treit, Jens J Holst, Filip K Knop, Tina Vilsbøll, Anders Junker, Stephan Sachs, Kerstin Stemmer, Timo D Müller, Matthias H Tschöp, Susanna M Hofmann, Matthias Mann
Plasma proteome profiling discovers novel proteins associated with non‐alcoholic fatty liver disease
published pages: e8793, ISSN: 1744-4292, DOI: 10.15252/msb.20188793
Molecular Systems Biology 15/3 2020-01-30
2019 Fabian Coscia, Sophia Doll, Jacob Mathias Bech, Andreas Mund, Ernst Lengyel, Jan Lindebjerg, Gunvor Iben Madsen, José M. A. Moreira, Matthias Mann
A streamlined mass spectrometry-based proteomics workflow for large scale FFPE tissue analysis
published pages: , ISSN: , DOI: 10.1101/779009
bioRxiv 2020-01-30
2018 Christian D. Kelstrup, Konstantin Aizikov, Tanveer S. Batth, Arne Kreutzman, Dmitry Grinfeld, Oliver Lange, Daniel Mourad, Alexander A. Makarov, Jesper V. Olsen
Limits for Resolving Isobaric Tandem Mass Tag Reporter Ions Using Phase-Constrained Spectrum Deconvolution
published pages: 4008-4016, ISSN: 1535-3893, DOI: 10.1021/acs.jproteome.8b00381
Journal of Proteome Research 17/11 2020-01-30
2018 Clement M. Potel, Miao-Hsia Lin, Albert J. R. Heck, Simone Lemeer
Defeating Major Contaminants in Fe 3+ - Immobilized Metal Ion Affinity Chromatography (IMAC) Phosphopeptide Enrichment
published pages: 1028-1034, ISSN: 1535-9476, DOI: 10.1074/mcp.tir117.000518
Molecular & Cellular Proteomics 17/5 2020-01-29
2018 Yasset Perez-Riverol, Attila Csordas, Jingwen Bai, Manuel Bernal-Llinares, Suresh Hewapathirana, Deepti J Kundu, Avinash Inuganti, Johannes Griss, Gerhard Mayer, Martin Eisenacher, Enrique Pérez, Julian Uszkoreit, Julianus Pfeuffer, Timo Sachsenberg, Şule Yılmaz, Shivani Tiwary, Jürgen Cox, Enrique Audain, Mathias Walzer, Andrew F Jarnuczak, Tobias Ternent, Alvis Brazma, Juan Antonio Vizcaíno
The PRIDE database and related tools and resources in 2019: improving support for quantification data
published pages: D442-D450, ISSN: 0305-1048, DOI: 10.1093/nar/gky1106
Nucleic Acids Research 47/D1 2019-11-25
2019 Jan Daniel Rudolph, Jürgen Cox
A Network Module for the Perseus Software for Computational Proteomics Facilitates Proteome Interaction Graph Analysis
published pages: 2052-2064, ISSN: 1535-3893, DOI: 10.1021/acs.jproteome.8b00927
Journal of Proteome Research 18/5 2019-11-22
2018 Nicolai Bache, Philipp E. Geyer, Dorte B. Bekker-Jensen, Ole Hoerning, Lasse Falkenby, Peter V. Treit, Sophia Doll, Igor Paron, Johannes B. Müller, Florian Meier, Jesper V. Olsen, Ole Vorm, Matthias Mann
A Novel LC System Embeds Analytes in Pre-formed Gradients for Rapid, Ultra-robust Proteomics
published pages: 2284-2296, ISSN: 1535-9476, DOI: 10.1074/mcp.TIR118.000853
Molecular & Cellular Proteomics 17/11 2019-11-22
2018 Jennie R. Lill, Peter A. van Veelen, Stefan Tenzer, Arie Admon, Etienne Caron, Joshua E. Elias, Albert J.R. Heck, Miguel Marcilla, Fabio Marino, Markus Müller, Bjoern Peters, Anthony Purcell, Alessandro Sette, Theo Sturm, Nicola Ternette, Juan Antonio Vizcaíno, Michal Bassani-Sternberg
Minimal Information About an Immuno-Peptidomics Experiment (MIAIPE)
published pages: 1800110, ISSN: 1615-9853, DOI: 10.1002/pmic.201800110
PROTEOMICS 18/12 2019-04-30
2018 Nicolai J. Wewer Albrechtsen, Philipp E. Geyer, Sophia Doll, Peter V. Treit, Kirstine N. Bojsen-Møller, Christoffer Martinussen, Nils B. Jørgensen, Signe S. Torekov, Florian Meier, Lili Niu, Alberto Santos, Eva C. Keilhauer, Jens J. Holst, Sten Madsbad, Matthias Mann
Plasma Proteome Profiling Reveals Dynamics of Inflammatory and Lipid Homeostasis Markers after Roux-En-Y Gastric Bypass Surgery
published pages: 601-612.e3, ISSN: 2405-4712, DOI: 10.1016/j.cels.2018.10.012
Cell Systems 7/6 2019-04-30
2018 Magnus E. Jakobsson, Jędrzej M. Małecki, Levon Halabelian, Benedikt S. Nilges, Rita Pinto, Srikanth Kudithipudi, Stephanie Munk, Erna Davydova, Fawzi R. Zuhairi, Cheryl H. Arrowsmith, Albert Jeltsch, Sebastian A. Leidel, Jesper V. Olsen, Pål Ø. Falnes
The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates
published pages: 3411, ISSN: 2041-1723, DOI: 10.1038/s41467-018-05646-y
Nature Communications 9/1 2019-04-30
2018 Yu-Hsien Lin, Vojtech Franc, Albert J. R. Heck
Similar Albeit Not the Same: In-Depth Analysis of Proteoforms of Human Serum, Bovine Serum, and Recombinant Human Fetuin
published pages: 2861-2869, ISSN: 1535-3893, DOI: 10.1021/acs.jproteome.8b00318
Journal of Proteome Research 17/8 2019-04-30
2018 Ashley L. Comes, Sergi Papiol, Thorsten Mueller, Philipp E. Geyer, Matthias Mann, Thomas G. Schulze
Proteomics for blood biomarker exploration of severe mental illness: pitfalls of the past and potential for the future
published pages: 160, ISSN: 2158-3188, DOI: 10.1038/s41398-018-0219-2
Translational Psychiatry 8/1 2019-04-30
2016 Kyle L. Fort, Andrey Dyachenko, Clement M. Potel, Eleonora Corradini, Fabio Marino, Arjan Barendregt, Alexander A. Makarov, Richard A. Scheltema, Albert J. R. Heck
Implementation of Ultraviolet Photodissociation on a Benchtop Q Exactive Mass Spectrometer and Its Application to Phosphoproteomics
published pages: 2303-2310, ISSN: 0003-2700, DOI: 10.1021/acs.analchem.5b04162
Analytical Chemistry 88/4 2019-04-30
2016 Philip Lössl, Andrea M. Brunner, Fan Liu, Aneika C. Leney, Masami Yamashita, Richard A. Scheltema, Albert J. R. Heck
Deciphering the Interplay among Multisite Phosphorylation, Interaction Dynamics, and Conformational Transitions in a Tripartite Protein System
published pages: 445-455, ISSN: 2374-7943, DOI: 10.1021/acscentsci.6b00053
ACS Central Science 2/7 2019-04-30
2016 Sem Tamara, Andrey Dyachenko, Kyle L. Fort, Alexander A. Makarov, Richard A. Scheltema, Albert J. R. Heck
Symmetry of Charge Partitioning in Collisional and UV Photon-Induced Dissociation of Protein Assemblies
published pages: 10860-10868, ISSN: 0002-7863, DOI: 10.1021/jacs.6b05147
Journal of the American Chemical Society 138/34 2019-04-30
2016 Philip Lössl, Michiel van de Waterbeemd, Albert JR Heck
The diverse and expanding role of mass spectrometry in structural and molecular biology
published pages: 2634-2657, ISSN: 0261-4189, DOI: 10.15252/embj.201694818
The EMBO Journal 35/24 2019-04-30
2016 Dmitry Grinfeld, Konstantin Aizikov, Arne Kreutzmann, Eugen Damoc, Alexander Makarov
Phase-Constrained Spectrum Deconvolution for Fourier Transform Mass Spectrometry
published pages: , ISSN: 0003-2700, DOI: 10.1021/acs.analchem.6b03636
Analytical Chemistry 2019-04-30
2016 Chiara Francavilla, Moreno Papetti, Kristoffer T G Rigbolt, Anna-Kathrine Pedersen, Jon O Sigurdsson, Giuseppe Cazzamali, Gopal Karemore, Blagoy Blagoev, Jesper V Olsen
Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking
published pages: 608-618, ISSN: 1545-9993, DOI: 10.1038/nsmb.3218
Nature Structural & Molecular Biology 23/6 2019-04-30
2016 Anna Secher, Christian D. Kelstrup, Kilian W. Conde-Frieboes, Charles Pyke, Kirsten Raun, Birgitte S. Wulff, Jesper V. Olsen
Analytic framework for peptidomics applied to large-scale neuropeptide identification
published pages: 11436, ISSN: 2041-1723, DOI: 10.1038/ncomms11436
Nature Communications 7 2019-04-30
2016 Yang Yang, Fan Liu, Vojtech Franc, Liem Andhyk Halim, Huub Schellekens, Albert J. R. Heck
Hybrid mass spectrometry approaches in glycoprotein analysis and their usage in scoring biosimilarity
published pages: 13397, ISSN: 2041-1723, DOI: 10.1038/ncomms13397
Nature Communications 7 2019-04-30
2016 Stefka Tyanova, Tikira Temu, Pavel Sinitcyn, Arthur Carlson, Marco Y Hein, Tamar Geiger, Matthias Mann, Jürgen Cox
The Perseus computational platform for comprehensive analysis of (prote)omics data
published pages: 731-740, ISSN: 1548-7091, DOI: 10.1038/nmeth.3901
Nature Methods 13/9 2019-04-30

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