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Meta-biomaterials: 3D printing meets Origami

Total Cost €


EC-Contrib. €






 BIO-ORIGAMI project word cloud

Explore the words cloud of the BIO-ORIGAMI project. It provides you a very rough idea of what is the project "BIO-ORIGAMI" about.

distributions    transport    structure    tissue    owing    curvatures    gives    regeneration    extra    designed    preferable    dimension    nano    sheet    subjected    materials    deadlock    mechanical    create    manufactured    crease    japanese    rate    few    3d    techniques    patterns    sheets    origami    paper    diffusivity    models    desired    surfaces    negative    assays    stiffness    nature    combining    stem    behavior    permeability    nutrients    animal    creates    knows    geometrical    decorate    extraordinary    added    surface    fold    unprecedented    ancient    self    meta    precisely    class    bone    oxygen    nanometers    mass    structures    folding    solving    thickness    introduces    material    halfway    communicate    optimize    nanolithography    shapes    loads    biological    printing    direct    combination    unusual    printed    flat    cell    differentiation    joints    vitro    cells    decorated    first    culture    biomaterials    rare    compression    instability    groundbreaking    adding   

Project "BIO-ORIGAMI" data sheet

The following table provides information about the project.


Organization address
address: STEVINWEG 1
city: DELFT
postcode: 2628 CN

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 1˙499˙600 €
 EC max contribution 1˙499˙600 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2015-STG
 Funding Scheme ERC-STG
 Starting year 2016
 Duration (year-month-day) from 2016-02-01   to  2021-01-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TECHNISCHE UNIVERSITEIT DELFT NL (DELFT) coordinator 1˙499˙600.00


 Project objective

Meta-materials, best known for their extraordinary properties (e.g. negative stiffness), are halfway from both materials and structures: their unusual properties are direct results of their complex 3D structures. This project introduces a new class of meta-materials called meta-biomaterials. Meta-biomaterials go beyond meta-materials by adding an extra dimension to the complex 3D structure, i.e. complex and precisely controlled surface nano-patterns. The 3D structure gives rise to unprecedented or rare combination of mechanical (e.g. stiffness), mass transport (e.g. permeability, diffusivity), and biological (e.g. tissue regeneration rate) properties. Those properties optimize the distribution of mechanical loads and the transport of nutrients and oxygen while providing geometrical shapes preferable for tissue regeneration (e.g. higher curvatures). Surface nano-patterns communicate with (stem) cells, control their differentiation behavior, and enhance tissue regeneration. There is one important problem: meta-biomaterials cannot be manufactured with current technology. 3D printing can create complex shapes while nanolithography creates complex surface nano-patterns down to a few nanometers but only on flat surfaces. There is, however, no way of combining complex shapes with complex surface nano-patterns. The groundbreaking nature of this project is in solving that deadlock using the Origami concept (the ancient Japanese art of paper folding). In this approach, I first decorate flat 3D-printed sheets with nano-patterns. Then, I apply Origami techniques to fold the decorated flat sheet and create complex 3D shapes. The sheet knows how to self-fold to the desired structure when subjected to compression, owing to pre-designed joints, crease patterns, and thickness/material distributions that control its mechanical instability. I will demonstrate the added value of meta-biomaterials in improving bone tissue regeneration using in vitro cell culture assays and animal models


year authors and title journal last update
List of publications.
2017 Teunis van Manen, Shahram Janbaz, Amir A. Zadpoor
Programming 2D/3D shape-shifting with hobbyist 3D printers
published pages: , ISSN: 2051-6347, DOI: 10.1039/C7MH00269F
Mater. Horiz. 2019-07-08
2018 Sebastien J.P. Callens, Amir A. Zadpoor
From flat sheets to curved geometries: Origami and kirigami approaches
published pages: 241-264, ISSN: 1369-7021, DOI: 10.1016/j.mattod.2017.10.004
Materials Today 21/3 2019-04-01
2018 Teunis van Manen, Shahram Janbaz, Amir A. Zadpoor
Programming the shape-shifting of flat soft matter
published pages: 144-163, ISSN: 1369-7021, DOI: 10.1016/j.mattod.2017.08.026
Materials Today 21/2 2019-04-01
2017 Shahram Janbaz, Niels Noordzij, Dwisetya S. Widyaratih, Cornelis W. Hagen, Lidy E. Fratila-Apachitei, Amir A. Zadpoor
Origami lattices with free-form surface ornaments
published pages: eaao1595, ISSN: 2375-2548, DOI: 10.1126/sciadv.aao1595
Science Advances 3/11 2019-04-01

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The information about "BIO-ORIGAMI" are provided by the European Opendata Portal: CORDIS opendata.

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