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BIO-ORIGAMI SIGNED

Meta-biomaterials: 3D printing meets Origami

Total Cost €

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EC-Contrib. €

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Partnership

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 BIO-ORIGAMI project word cloud

Explore the words cloud of the BIO-ORIGAMI project. It provides you a very rough idea of what is the project "BIO-ORIGAMI" about.

vitro    few    gives    subjected    stem    nano    mass    culture    self    oxygen    distributions    combination    thickness    behavior    bone    designed    decorate    loads    joints    flat    first    cells    instability    unusual    groundbreaking    deadlock    nanometers    manufactured    introduces    animal    structures    extra    creates    mechanical    sheets    crease    sheet    printing    meta    nature    solving    rate    patterns    optimize    desired    nutrients    structure    nanolithography    shapes    tissue    surface    curvatures    cell    compression    assays    decorated    adding    added    halfway    techniques    permeability    preferable    combining    paper    japanese    transport    knows    diffusivity    precisely    class    ancient    extraordinary    printed    negative    folding    rare    geometrical    direct    surfaces    materials    origami    fold    3d    regeneration    biological    biomaterials    unprecedented    communicate    owing    stiffness    dimension    differentiation    material    models    create   

Project "BIO-ORIGAMI" data sheet

The following table provides information about the project.

Coordinator
TECHNISCHE UNIVERSITEIT DELFT 

Organization address
address: STEVINWEG 1
city: DELFT
postcode: 2628 CN
website: www.tudelft.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 1˙499˙600 €
 EC max contribution 1˙499˙600 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2015-STG
 Funding Scheme ERC-STG
 Starting year 2016
 Duration (year-month-day) from 2016-02-01   to  2021-01-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TECHNISCHE UNIVERSITEIT DELFT NL (DELFT) coordinator 1˙499˙600.00

Map

 Project objective

Meta-materials, best known for their extraordinary properties (e.g. negative stiffness), are halfway from both materials and structures: their unusual properties are direct results of their complex 3D structures. This project introduces a new class of meta-materials called meta-biomaterials. Meta-biomaterials go beyond meta-materials by adding an extra dimension to the complex 3D structure, i.e. complex and precisely controlled surface nano-patterns. The 3D structure gives rise to unprecedented or rare combination of mechanical (e.g. stiffness), mass transport (e.g. permeability, diffusivity), and biological (e.g. tissue regeneration rate) properties. Those properties optimize the distribution of mechanical loads and the transport of nutrients and oxygen while providing geometrical shapes preferable for tissue regeneration (e.g. higher curvatures). Surface nano-patterns communicate with (stem) cells, control their differentiation behavior, and enhance tissue regeneration. There is one important problem: meta-biomaterials cannot be manufactured with current technology. 3D printing can create complex shapes while nanolithography creates complex surface nano-patterns down to a few nanometers but only on flat surfaces. There is, however, no way of combining complex shapes with complex surface nano-patterns. The groundbreaking nature of this project is in solving that deadlock using the Origami concept (the ancient Japanese art of paper folding). In this approach, I first decorate flat 3D-printed sheets with nano-patterns. Then, I apply Origami techniques to fold the decorated flat sheet and create complex 3D shapes. The sheet knows how to self-fold to the desired structure when subjected to compression, owing to pre-designed joints, crease patterns, and thickness/material distributions that control its mechanical instability. I will demonstrate the added value of meta-biomaterials in improving bone tissue regeneration using in vitro cell culture assays and animal models

 Publications

year authors and title journal last update
List of publications.
2017 Teunis van Manen, Shahram Janbaz, Amir A. Zadpoor
Programming 2D/3D shape-shifting with hobbyist 3D printers
published pages: , ISSN: 2051-6347, DOI: 10.1039/C7MH00269F
Mater. Horiz. 2019-07-08
2018 Sebastien J.P. Callens, Amir A. Zadpoor
From flat sheets to curved geometries: Origami and kirigami approaches
published pages: 241-264, ISSN: 1369-7021, DOI: 10.1016/j.mattod.2017.10.004
Materials Today 21/3 2019-04-01
2018 Teunis van Manen, Shahram Janbaz, Amir A. Zadpoor
Programming the shape-shifting of flat soft matter
published pages: 144-163, ISSN: 1369-7021, DOI: 10.1016/j.mattod.2017.08.026
Materials Today 21/2 2019-04-01
2017 Shahram Janbaz, Niels Noordzij, Dwisetya S. Widyaratih, Cornelis W. Hagen, Lidy E. Fratila-Apachitei, Amir A. Zadpoor
Origami lattices with free-form surface ornaments
published pages: eaao1595, ISSN: 2375-2548, DOI: 10.1126/sciadv.aao1595
Science Advances 3/11 2019-04-01

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The information about "BIO-ORIGAMI" are provided by the European Opendata Portal: CORDIS opendata.

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