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BIO-ORIGAMI SIGNED

Meta-biomaterials: 3D printing meets Origami

Total Cost €

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EC-Contrib. €

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Partnership

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 BIO-ORIGAMI project word cloud

Explore the words cloud of the BIO-ORIGAMI project. It provides you a very rough idea of what is the project "BIO-ORIGAMI" about.

desired    mechanical    nano    distributions    stiffness    crease    combining    japanese    regeneration    precisely    knows    oxygen    subjected    flat    extra    rate    nature    decorate    fold    combination    shapes    unprecedented    unusual    cells    transport    groundbreaking    extraordinary    biomaterials    gives    preferable    techniques    first    rare    models    vitro    material    loads    curvatures    printed    materials    designed    printing    surface    compression    animal    nanolithography    cell    manufactured    tissue    culture    introduces    instability    few    geometrical    diffusivity    behavior    nanometers    joints    paper    solving    thickness    ancient    assays    added    create    patterns    direct    communicate    negative    folding    meta    creates    halfway    3d    dimension    deadlock    surfaces    permeability    owing    nutrients    structures    optimize    structure    origami    sheet    decorated    stem    bone    self    sheets    adding    biological    mass    class    differentiation   

Project "BIO-ORIGAMI" data sheet

The following table provides information about the project.

Coordinator
TECHNISCHE UNIVERSITEIT DELFT 

Organization address
address: STEVINWEG 1
city: DELFT
postcode: 2628 CN
website: www.tudelft.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 1˙499˙600 €
 EC max contribution 1˙499˙600 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2015-STG
 Funding Scheme ERC-STG
 Starting year 2016
 Duration (year-month-day) from 2016-02-01   to  2021-01-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TECHNISCHE UNIVERSITEIT DELFT NL (DELFT) coordinator 1˙499˙600.00

Map

 Project objective

Meta-materials, best known for their extraordinary properties (e.g. negative stiffness), are halfway from both materials and structures: their unusual properties are direct results of their complex 3D structures. This project introduces a new class of meta-materials called meta-biomaterials. Meta-biomaterials go beyond meta-materials by adding an extra dimension to the complex 3D structure, i.e. complex and precisely controlled surface nano-patterns. The 3D structure gives rise to unprecedented or rare combination of mechanical (e.g. stiffness), mass transport (e.g. permeability, diffusivity), and biological (e.g. tissue regeneration rate) properties. Those properties optimize the distribution of mechanical loads and the transport of nutrients and oxygen while providing geometrical shapes preferable for tissue regeneration (e.g. higher curvatures). Surface nano-patterns communicate with (stem) cells, control their differentiation behavior, and enhance tissue regeneration. There is one important problem: meta-biomaterials cannot be manufactured with current technology. 3D printing can create complex shapes while nanolithography creates complex surface nano-patterns down to a few nanometers but only on flat surfaces. There is, however, no way of combining complex shapes with complex surface nano-patterns. The groundbreaking nature of this project is in solving that deadlock using the Origami concept (the ancient Japanese art of paper folding). In this approach, I first decorate flat 3D-printed sheets with nano-patterns. Then, I apply Origami techniques to fold the decorated flat sheet and create complex 3D shapes. The sheet knows how to self-fold to the desired structure when subjected to compression, owing to pre-designed joints, crease patterns, and thickness/material distributions that control its mechanical instability. I will demonstrate the added value of meta-biomaterials in improving bone tissue regeneration using in vitro cell culture assays and animal models

 Publications

year authors and title journal last update
List of publications.
2017 Teunis van Manen, Shahram Janbaz, Amir A. Zadpoor
Programming 2D/3D shape-shifting with hobbyist 3D printers
published pages: , ISSN: 2051-6347, DOI: 10.1039/C7MH00269F
Mater. Horiz. 2019-07-08
2018 Sebastien J.P. Callens, Amir A. Zadpoor
From flat sheets to curved geometries: Origami and kirigami approaches
published pages: 241-264, ISSN: 1369-7021, DOI: 10.1016/j.mattod.2017.10.004
Materials Today 21/3 2019-04-01
2018 Teunis van Manen, Shahram Janbaz, Amir A. Zadpoor
Programming the shape-shifting of flat soft matter
published pages: 144-163, ISSN: 1369-7021, DOI: 10.1016/j.mattod.2017.08.026
Materials Today 21/2 2019-04-01
2017 Shahram Janbaz, Niels Noordzij, Dwisetya S. Widyaratih, Cornelis W. Hagen, Lidy E. Fratila-Apachitei, Amir A. Zadpoor
Origami lattices with free-form surface ornaments
published pages: eaao1595, ISSN: 2375-2548, DOI: 10.1126/sciadv.aao1595
Science Advances 3/11 2019-04-01

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The information about "BIO-ORIGAMI" are provided by the European Opendata Portal: CORDIS opendata.

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