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BIO-ORIGAMI SIGNED

Meta-biomaterials: 3D printing meets Origami

Total Cost €

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EC-Contrib. €

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Partnership

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 BIO-ORIGAMI project word cloud

Explore the words cloud of the BIO-ORIGAMI project. It provides you a very rough idea of what is the project "BIO-ORIGAMI" about.

nutrients    rare    precisely    create    techniques    desired    material    gives    transport    curvatures    extra    nanolithography    decorated    fold    materials    creates    meta    assays    biological    sheet    folding    optimize    self    distributions    bone    communicate    instability    subjected    dimension    japanese    ancient    flat    joints    structure    culture    extraordinary    compression    behavior    printing    halfway    structures    paper    permeability    surface    cells    unusual    designed    printed    decorate    owing    mechanical    unprecedented    negative    combination    differentiation    nature    preferable    oxygen    first    manufactured    deadlock    solving    class    vitro    3d    models    patterns    diffusivity    origami    direct    crease    animal    nano    few    nanometers    sheets    combining    introduces    thickness    tissue    knows    groundbreaking    cell    geometrical    surfaces    adding    mass    biomaterials    regeneration    added    stem    stiffness    shapes    loads    rate   

Project "BIO-ORIGAMI" data sheet

The following table provides information about the project.

Coordinator
TECHNISCHE UNIVERSITEIT DELFT 

Organization address
address: STEVINWEG 1
city: DELFT
postcode: 2628 CN
website: www.tudelft.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 1˙499˙600 €
 EC max contribution 1˙499˙600 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2015-STG
 Funding Scheme ERC-STG
 Starting year 2016
 Duration (year-month-day) from 2016-02-01   to  2021-01-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TECHNISCHE UNIVERSITEIT DELFT NL (DELFT) coordinator 1˙499˙600.00

Map

 Project objective

Meta-materials, best known for their extraordinary properties (e.g. negative stiffness), are halfway from both materials and structures: their unusual properties are direct results of their complex 3D structures. This project introduces a new class of meta-materials called meta-biomaterials. Meta-biomaterials go beyond meta-materials by adding an extra dimension to the complex 3D structure, i.e. complex and precisely controlled surface nano-patterns. The 3D structure gives rise to unprecedented or rare combination of mechanical (e.g. stiffness), mass transport (e.g. permeability, diffusivity), and biological (e.g. tissue regeneration rate) properties. Those properties optimize the distribution of mechanical loads and the transport of nutrients and oxygen while providing geometrical shapes preferable for tissue regeneration (e.g. higher curvatures). Surface nano-patterns communicate with (stem) cells, control their differentiation behavior, and enhance tissue regeneration. There is one important problem: meta-biomaterials cannot be manufactured with current technology. 3D printing can create complex shapes while nanolithography creates complex surface nano-patterns down to a few nanometers but only on flat surfaces. There is, however, no way of combining complex shapes with complex surface nano-patterns. The groundbreaking nature of this project is in solving that deadlock using the Origami concept (the ancient Japanese art of paper folding). In this approach, I first decorate flat 3D-printed sheets with nano-patterns. Then, I apply Origami techniques to fold the decorated flat sheet and create complex 3D shapes. The sheet knows how to self-fold to the desired structure when subjected to compression, owing to pre-designed joints, crease patterns, and thickness/material distributions that control its mechanical instability. I will demonstrate the added value of meta-biomaterials in improving bone tissue regeneration using in vitro cell culture assays and animal models

 Publications

year authors and title journal last update
List of publications.
2017 Teunis van Manen, Shahram Janbaz, Amir A. Zadpoor
Programming 2D/3D shape-shifting with hobbyist 3D printers
published pages: , ISSN: 2051-6347, DOI: 10.1039/C7MH00269F
Mater. Horiz. 2019-07-08
2018 Sebastien J.P. Callens, Amir A. Zadpoor
From flat sheets to curved geometries: Origami and kirigami approaches
published pages: 241-264, ISSN: 1369-7021, DOI: 10.1016/j.mattod.2017.10.004
Materials Today 21/3 2019-04-01
2018 Teunis van Manen, Shahram Janbaz, Amir A. Zadpoor
Programming the shape-shifting of flat soft matter
published pages: 144-163, ISSN: 1369-7021, DOI: 10.1016/j.mattod.2017.08.026
Materials Today 21/2 2019-04-01
2017 Shahram Janbaz, Niels Noordzij, Dwisetya S. Widyaratih, Cornelis W. Hagen, Lidy E. Fratila-Apachitei, Amir A. Zadpoor
Origami lattices with free-form surface ornaments
published pages: eaao1595, ISSN: 2375-2548, DOI: 10.1126/sciadv.aao1595
Science Advances 3/11 2019-04-01

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The information about "BIO-ORIGAMI" are provided by the European Opendata Portal: CORDIS opendata.

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