TRANSBIO
Cellular BIOtechnology for prognosis and monitoring in renal TRANSplantation
Total Cost €
0EC-Contrib. €
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Explore the words cloud of the TRANSBIO project. It provides you a very rough idea of what is the project "TRANSBIO" about.
Project "TRANSBIO" data sheet
The following table provides information about the project.
| Coordinator |
BIOHOPE SCIENTIFIC SOLUTIONS FOR HUMAN HEALTH SL
Organization address contact info |
| Coordinator Country | Spain [ES] |
| Project website | https://transbiohope.eu/ |
| Total cost | 3˙846˙640 € |
| EC max contribution | 3˙845˙140 € (100%) |
| Programme |
1. H2020-EU.3.1.3. (Treating and managing disease) |
| Code Call | H2020-SMEINST-2-2016-2017 |
| Funding Scheme | SME-2 |
| Starting year | 2017 |
| Duration (year-month-day) | from 2017-01-01 to 2019-06-30 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | BIOHOPE SCIENTIFIC SOLUTIONS FOR HUMAN HEALTH SL | ES (TRES CANTOS MADRID) | coordinator | 3˙845˙140.00 |
Map
Project objective
Kidney transplantation is the treatment of choice for patients with end-stage kidney disease (ESKD). However, although surgical techniques and postoperative care have greatly advanced, renal transplantation is not empty of challenges. The most important challenge is to achieve the long-term survival of the transplanted organ. Graft survival depends on the ability of the recipe of not rejecting the “foreign organ”. Rejection is a naturally occurring process triggered by a biological response of the immune system, which main function in the body is to defend it against infectious organisms and other invaders. As such, the immune system is prepared to reject a “foreign organ”, something that is nowadays prevented by prescribing immunosuppressive therapies to the patients for their whole life. However, the use of immunosuppressive therapies entails important problems. On one side, suppressing the immune system implies severe side effects like opportunistic infections, cancer and other severe malignancies. On the other side, even under immunosuppressive therapies, about 50% of transplanted kidneys are lost during the first 10 years and this is because of an immune response usually described as chronic rejection. Therefore, the major challenges in ESKD deal with avoiding the side effects associated with immunosuppressant drugs and avoiding chronic rejection. In the TRANSBIO project we aim at bringing to the healthcare market a technology for efficient clinical management of patients undergoing a kidney transplant based on a simple and non-invasive blood test. Considering that worldwide, the number of people receiving renal transplantation annually is estimated at about 80,000 people, growing by approximately 6% annually and representing a prevalence of about 700 patients per million population, or what is the same about 5 million people living with a transplanted kidney, the TRANSBIO business opportunity seems unquestionable.
Deliverables
| TRANSBIO webpage | Websites, patent fillings, videos etc. | 2020-02-27 11:28:30 |
Take a look to the deliverables list in detail: detailed list of TRANSBIO deliverables.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2018 |
M. Di Scala1, J. Portolés2, C. Jiménez3, D. Janeiro2, E. González3, B. Sánchez Sobrino2, M. López Oliva3, J. Richter1, A. Ortega1, J. Pascual4, I. Portero1;
1 BIOHOPE Scientific SL, Madrid, Spain
2 Hospital Universitario Puerta de Hierro, Nephrology Department, Madrid, Spain,
3 Hospital La Paz, Nephrology Department, Madrid, Spain,
4 Hospital del Mar, Nephrology Department and Kidney Transplantation, Barcelona, Spain. IMMUNOBIOGRAM a new immunological tool to personalize immunosuppressive therapy in kidney transplant recipients published pages: https://www.eci2, ISSN: , DOI: |
Abstracts Book, 5th European Congress of Immunology, 2-5 September Amsterdam Annual | 2020-02-27 |
| 2018 |
Ortega-Carrión Ãlvaro1, Di Scala Marianna1, Yebra Tatiana1, Diez Teresa 1, Richter Jose1, Portero Isabel1
1 BIOHOPE Scientific SL, Tres Cantos, Madrid, Spain Immunobiogram: Patterns of resistance to immunomodulatory treatment in patients with chronic inflammatory diseases published pages: https://www.eci2, ISSN: , DOI: |
Abstracts Book, 5th European Congress of Immunology, 2-5 September Amsterdam Annual | 2020-02-27 |
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The information about "TRANSBIO" are provided by the European Opendata Portal: CORDIS opendata.
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