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Role of alternative splicing in cell expansion and plant growth

Total Cost €


EC-Contrib. €






Project "AS-CELLEXPAND" data sheet

The following table provides information about the project.


Organization address
address: AVENIDA BERNA 45
city: LISBOA
postcode: 1000

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Portugal [PT]
 Total cost 148˙635 €
 EC max contribution 148˙635 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-09-01   to  2020-08-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FUNDACAO CALOUSTE GULBENKIAN PT (LISBOA) coordinator 148˙635.00


 Project objective

Plant growth and morphogenic changes in response to developmental and environmental cues depend on the capacity of cells to expand correctly, which requires structural remodeling of cell walls. Importantly, abiotic stress markedly impacts plant growth by affecting many aspects related to the cell wall, from its composition to the expression of biosynthetic and remodeling genes. The importance of transcriptional regulation of genes controlling cell wall biosynthesis and architecture in response to environmental cues is well studied, but little is known about posttranscriptional mechanisms that affect their function. SR (serine/arginine-rich) proteins are major regulators of alternative splicing (AS), which generates multiple transcripts from the same gene and may modulate plant stress responses. Given evidence that (i) abiotic stress affects SR protein function; (ii) mutations in SR genes cause abnormal plant growth; and (iii) SR45 directly binds mRNAs encoding cell wall regulators, this project will investigate a role for SR-mediated regulation of AS events in cell wall regulators during plant development and abiotic stress responses. Specific objectives are to: (i) identify AS events in cell wall regulator genes that may impact plant growth; (ii) study their regulation by SR proteins; and (iii) assess whether they determine normal plant growth under environmental stress.

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The information about "AS-CELLEXPAND" are provided by the European Opendata Portal: CORDIS opendata.

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