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ZEBRAONCOFISH SIGNED

Zebrafish avatar as a real-time in vivo platform for personalized cancer therapeutics

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 ZEBRAONCOFISH project word cloud

Explore the words cloud of the ZEBRAONCOFISH project. It provides you a very rough idea of what is the project "ZEBRAONCOFISH" about.

mean    ultimate    made    patient    personalized    decisions    subjacent    assays    opportunity    genetic    biology    roadmap    performed    presented    profile    425    biological    team    commercialization    influence    anticancer    hospitals    mortality    solutions    solution    lines    actionable    progression    drugs    directed    biotechnological    makeup    guide    35    onset    complete    close    differently    morbidity    cell    tumor    disease    platform    tax    remarkable    interspecies    extensive    healthcare    display    cancerous    treatment    market    cancer    avatars    complexity    xenotransplantation    found    underlying    carry    human    acquired    created    difficulty    understand    lab    zebraoncofish    metabolic    million    therapeutic    estimations    living    transplant    treatments    tailor    therapy    time    samples    deaths    zebrafish    vivo    effect    thanks    interventions    approx    tubes    individual    mechanism    dynamic    chance    company    people    leader   

Project "ZEBRAONCOFISH" data sheet

The following table provides information about the project.

Coordinator
IKAN BIOTECH S.L. 

Organization address
address: CALLE CHAPITELA 20 1
city: PAMPLONA
postcode: 31001
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website http://zebraoncofish.com/
 Total cost 2˙004˙583 €
 EC max contribution 2˙004˙583 € (100%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-2-2016-2017
 Funding Scheme SME-2
 Starting year 2017
 Duration (year-month-day) from 2017-09-01   to  2020-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    IKAN BIOTECH S.L. ES (PAMPLONA) coordinator 2˙004˙583.00

Map

Leaflet | Map data © OpenStreetMap contributors, CC-BY-SA, Imagery © Mapbox

 Project objective

The Zebrafish Lab is a biotechnological company leader in the development and commercialization of novel, tailor-made solutions based on in vivo zebrafish assays. Thanks to the extensive knowledge acquired by the R&D projects performed in the field by our team for many years and a close collaboration with Hospitals and Cancer Research Institutions, we have identified a remarkable opportunity in the ZEBRAONCOFISH project that will mean a 5-year after tax-R.O.I of 425% according to our estimations. The ultimate goal of the project presented as ZEBRAONCOFISH is to complete the technical roadmap required to bring to the healthcare market a novel real time in vivo platform for personalized cancer treatment based on the use of zebrafish “avatars” as personalized, living test tubes. Cancer is a leading cause of morbidity and mortality with approx. 35 million people affected by this disease and more than 8 million deaths per year. A major difficulty found in effective cancer treatment is the complexity of the biological mechanism underlying cancer onset and disease progression. This is because the genetic makeup and metabolic profile of each individual patient influence the effect of anticancer drugs. As such, different people respond differently to the same therapy. The solution we propose in the ZEBRAONCOFISH project is the use of zebrafish avatars as an in vivo platform to guide therapeutic decisions in actionable cancer patient-directed interventions. These avatars will be created by xenotransplantation (interspecies transplant) of human cancer cell lines/ tumor samples in zebrafish. The chance to carry out a dynamic display of the cancerous process in vivo will offer the unique opportunity to understand the subjacent cancer biology and design tailor-made treatments for each patient.

 Deliverables

List of deliverables.
ZEBRAONCOFISH webpage Websites, patent fillings, videos etc. 2020-04-24 04:18:30

Take a look to the deliverables list in detail:  detailed list of ZEBRAONCOFISH deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Letrado P, de Miguel I, Lamberto I, Díez-Martínez R, Oyarzabal J.
Zebrafish: Speeding up the Cancer Drug Discovery Process.
published pages: , ISSN: 0008-5472, DOI:
Cancer Research 2020-04-24

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The information about "ZEBRAONCOFISH" are provided by the European Opendata Portal: CORDIS opendata.

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