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ZEBRAONCOFISH SIGNED

Zebrafish avatar as a real-time in vivo platform for personalized cancer therapeutics

Total Cost €

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EC-Contrib. €

0

Partnership

0

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 ZEBRAONCOFISH project word cloud

Explore the words cloud of the ZEBRAONCOFISH project. It provides you a very rough idea of what is the project "ZEBRAONCOFISH" about.

therapeutic    opportunity    personalized    platform    samples    onset    tailor    understand    profile    actionable    chance    individual    mortality    living    mean    vivo    human    zebrafish    transplant    carry    treatment    hospitals    deaths    leader    directed    patient    tax    zebraoncofish    made    cancer    people    million    estimations    created    cell    makeup    solution    complexity    time    interspecies    tumor    lines    progression    lab    biology    interventions    differently    tubes    solutions    healthcare    difficulty    xenotransplantation    underlying    biotechnological    disease    extensive    genetic    mechanism    biological    treatments    company    guide    therapy    dynamic    subjacent    market    influence    drugs    anticancer    remarkable    ultimate    decisions    morbidity    avatars    approx    acquired    found    metabolic    roadmap    performed    cancerous    effect    team    close    commercialization    presented    425    thanks    35    display    assays    complete   

Project "ZEBRAONCOFISH" data sheet

The following table provides information about the project.

Coordinator
IKAN BIOTECH S.L. 

Organization address
address: CALLE CHAPITELA 20 1
city: PAMPLONA
postcode: 31001
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website http://zebraoncofish.com/
 Total cost 2˙004˙583 €
 EC max contribution 2˙004˙583 € (100%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-2-2016-2017
 Funding Scheme SME-2
 Starting year 2017
 Duration (year-month-day) from 2017-09-01   to  2020-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    IKAN BIOTECH S.L. ES (PAMPLONA) coordinator 2˙004˙583.00

Map

 Project objective

The Zebrafish Lab is a biotechnological company leader in the development and commercialization of novel, tailor-made solutions based on in vivo zebrafish assays. Thanks to the extensive knowledge acquired by the R&D projects performed in the field by our team for many years and a close collaboration with Hospitals and Cancer Research Institutions, we have identified a remarkable opportunity in the ZEBRAONCOFISH project that will mean a 5-year after tax-R.O.I of 425% according to our estimations. The ultimate goal of the project presented as ZEBRAONCOFISH is to complete the technical roadmap required to bring to the healthcare market a novel real time in vivo platform for personalized cancer treatment based on the use of zebrafish “avatars” as personalized, living test tubes. Cancer is a leading cause of morbidity and mortality with approx. 35 million people affected by this disease and more than 8 million deaths per year. A major difficulty found in effective cancer treatment is the complexity of the biological mechanism underlying cancer onset and disease progression. This is because the genetic makeup and metabolic profile of each individual patient influence the effect of anticancer drugs. As such, different people respond differently to the same therapy. The solution we propose in the ZEBRAONCOFISH project is the use of zebrafish avatars as an in vivo platform to guide therapeutic decisions in actionable cancer patient-directed interventions. These avatars will be created by xenotransplantation (interspecies transplant) of human cancer cell lines/ tumor samples in zebrafish. The chance to carry out a dynamic display of the cancerous process in vivo will offer the unique opportunity to understand the subjacent cancer biology and design tailor-made treatments for each patient.

 Deliverables

List of deliverables.
ZEBRAONCOFISH webpage Websites, patent fillings, videos etc. 2020-04-24 04:18:30

Take a look to the deliverables list in detail:  detailed list of ZEBRAONCOFISH deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Letrado P, de Miguel I, Lamberto I, Díez-Martínez R, Oyarzabal J.
Zebrafish: Speeding up the Cancer Drug Discovery Process.
published pages: , ISSN: 0008-5472, DOI:
Cancer Research 2020-04-24

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The information about "ZEBRAONCOFISH" are provided by the European Opendata Portal: CORDIS opendata.

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