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ZEBRAONCOFISH SIGNED

Zebrafish avatar as a real-time in vivo platform for personalized cancer therapeutics

Total Cost €

0

EC-Contrib. €

0

Partnership

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 Outcomes and results

 ZEBRAONCOFISH project word cloud

Explore the words cloud of the ZEBRAONCOFISH project. It provides you a very rough idea of what is the project "ZEBRAONCOFISH" about.

lines    solutions    thanks    tubes    transplant    acquired    created    genetic    solution    company    remarkable    individual    presented    personalized    samples    assays    million    35    decisions    underlying    complete    carry    progression    avatars    close    xenotransplantation    morbidity    makeup    disease    zebrafish    deaths    therapeutic    treatment    living    influence    zebraoncofish    market    directed    lab    anticancer    effect    guide    ultimate    approx    human    therapy    complexity    leader    estimations    team    425    drugs    opportunity    mean    roadmap    actionable    vivo    mechanism    cancer    difficulty    metabolic    biological    chance    hospitals    biotechnological    commercialization    made    cancerous    biology    profile    understand    found    onset    dynamic    cell    mortality    tax    display    tumor    interspecies    people    performed    extensive    patient    subjacent    treatments    differently    tailor    healthcare    interventions    platform    time   

Project "ZEBRAONCOFISH" data sheet

The following table provides information about the project.

Coordinator		 IKAN BIOTECH S.L. 

Organization address
address: CALLE CHAPITELA 20 1
city: PAMPLONA
postcode: 31001
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country Spain [ES]
 Project website http://zebraoncofish.com/
 Total cost 2˙004˙583 €
 EC max contribution 2˙004˙583 € (100%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-2-2016-2017
 Funding Scheme SME-2
 Starting year 2017
 Duration (year-month-day) from 2017-09-01   to  2020-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    IKAN BIOTECH S.L. ES (PAMPLONA) coordinator 2˙004˙583.00

Map

 Project objective

The Zebrafish Lab is a biotechnological company leader in the development and commercialization of novel, tailor-made solutions based on in vivo zebrafish assays. Thanks to the extensive knowledge acquired by the R&D projects performed in the field by our team for many years and a close collaboration with Hospitals and Cancer Research Institutions, we have identified a remarkable opportunity in the ZEBRAONCOFISH project that will mean a 5-year after tax-R.O.I of 425% according to our estimations. The ultimate goal of the project presented as ZEBRAONCOFISH is to complete the technical roadmap required to bring to the healthcare market a novel real time in vivo platform for personalized cancer treatment based on the use of zebrafish “avatars” as personalized, living test tubes. Cancer is a leading cause of morbidity and mortality with approx. 35 million people affected by this disease and more than 8 million deaths per year. A major difficulty found in effective cancer treatment is the complexity of the biological mechanism underlying cancer onset and disease progression. This is because the genetic makeup and metabolic profile of each individual patient influence the effect of anticancer drugs. As such, different people respond differently to the same therapy. The solution we propose in the ZEBRAONCOFISH project is the use of zebrafish avatars as an in vivo platform to guide therapeutic decisions in actionable cancer patient-directed interventions. These avatars will be created by xenotransplantation (interspecies transplant) of human cancer cell lines/ tumor samples in zebrafish. The chance to carry out a dynamic display of the cancerous process in vivo will offer the unique opportunity to understand the subjacent cancer biology and design tailor-made treatments for each patient.

 Deliverables

List of deliverables.
ZEBRAONCOFISH webpage Websites, patent fillings, videos etc. 2020-04-24 04:18:30

Take a look to the deliverables list in detail:  detailed list of ZEBRAONCOFISH deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Letrado P, de Miguel I, Lamberto I, Díez-Martínez R, Oyarzabal J.
Zebrafish: Speeding up the Cancer Drug Discovery Process.
published pages: , ISSN: 0008-5472, DOI: 		Cancer Research 2020-04-24

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The information about "ZEBRAONCOFISH" are provided by the European Opendata Portal: CORDIS opendata.

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