Opendata, web and dolomites

CANITEST

CANITEST: Proof-Of-Concept of a PCR test designed to identify the dogs carrying the more virulent strains of Capnocytophaga canimorsus

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

Project "CANITEST" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITE DE NAMUR ASBL 

Organization address
address: RUE DE BRUXELLES 61
city: NAMUR
postcode: 5000
website: www.unamur.be

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Belgium [BE]
 Total cost 150˙000 €
 EC max contribution 150˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-PoC
 Funding Scheme ERC-POC
 Starting year 2017
 Duration (year-month-day) from 2017-12-01   to  2019-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITE DE NAMUR ASBL BE (NAMUR) coordinator 150˙000.00

Map

 Project objective

The idea to be taken as proof of concept is drawn from the ERC Advanced grant N°293605-CAPCAN (2012-2016). This grant aimed at understanding the molecular and genetic bases of the dramatic human infections caused by Capnocytophaga canimorsus. One of the questions that we addressed in the frame of CAPCAN is why are there so few cases of human infections while so many dogs carry C. canimorsus? In other words, are all C. canimorsus strains equally dangerous and, if not, could we prevent the disease by detecting the dogs carrying the more dangerous strains? During CAPCAN, among others, we showed that C. canimorsus is endowed with a capsular polysaccharide (CPS) and its assembly pathway was characterized [1]. We also showed that the CPS of 25/25 strains isolated from human infections present a limited variability, with 3 dominant capsular serovars. In contrast, only 4 out of 52 C. canimorsus isolated from dog mouths did belong to these three serovars [2]. This implies that a small minority of dog-hosted C. canimorsus strains are virulent for humans than most strains and that these strains can be identified by capsular serotyping. We also set up a PCR test to achieve this capsular serotyping [2]. The proposal to be taken to proof of concept is to market the PCR test designed to identify the dogs carrying the more virulent strains of C. canimorsus.

 Publications

year authors and title journal last update
List of publications.
2018 Francesco Renzi, Estelle Hess, Melanie Dol, Dunia Koudad, Elodie Carlier, Maria Ohlén, Edward Moore, Guy Richard Cornelis
Capsular serovars of virulent Capnocytophaga canimorsus are shared by the closely related species C. canis and C. cynodegmi
published pages: 1-12, ISSN: 2222-1751, DOI: 10.1038/s41426-018-0126-x
Emerging Microbes & Infections 7/1 2019-10-28

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "CANITEST" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "CANITEST" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

ZARAH (2020)

Women’s labour activism in Eastern Europe and transnationally, from the age of empires to the late 20th century

Read More  

MOCHA (2019)

Understanding and leveraging ‘moments of change’ for pro-environmental behaviour shifts

Read More  

ChaperoneRegulome (2020)

ChaperoneRegulome: Understanding cell-type-specificity of chaperone regulation

Read More