Opendata, web and dolomites

PROMPT SIGNED

New generation of porphyrinoids for mitochondria-targeted photodynamic therapy

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

Project "PROMPT" data sheet

The following table provides information about the project.

Coordinator
CONSIGLIO NAZIONALE DELLE RICERCHE 

Organization address
address: PIAZZALE ALDO MORO 7
city: ROMA
postcode: 185
website: www.cnr.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Total cost 168˙277 €
 EC max contribution 168˙277 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2019
 Duration (year-month-day) from 2019-01-01   to  2020-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CONSIGLIO NAZIONALE DELLE RICERCHE IT (ROMA) coordinator 168˙277.00

Map

 Project objective

PROMPT will develop a new generation of photosensitizers targeting mitochondria in cancer cells, to be used in photodynamic therapy (PDT). The innovative approach of PROMPT is based on the design and synthesis of porphyrinoids functionalized with aromatic heterocyclic groups containing C-S bonds. These molecules are expected to localize specifically in mitochondria of cancer cells and to efficiently generate singlet oxygen, leading to apoptosis induction and cell death. Loading of the photosensitizers into liposomes ad hoc functionalized to target mitochondria is also envisaged in case of need. The innovative photodynamic treatment will thus show high selectivity, lower dose of treatment and reduced side effects with respect to the presently used phototherapy approaches. Moreover, the new molecules are expected to show significant two-photon absorption properties, due to the extended conjugation of the porphyrinoid core introduced by the aromatic side groups. They will thus represent a groundbreaking class of mitochondria-targeted photosensitizers for both one- and two-photon PDT. The multidisciplinarity of PROMPT, together with the proposed work plan in a forefront area of bio-medical research, will widen the scientific skills and technological know-how of the Experienced Researcher, significantly improving his career opportunities both in the academic and private sectors.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "PROMPT" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "PROMPT" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

NPsVLCD (2019)

Natural Product-Inspired Therapies for Leishmaniasis and Chagas Disease

Read More  

NaWaTL (2020)

Narrative, Writing, and the Teotihuacan Language: Exploring Language History Through Phylogenetics, Epigraphy and Iconography

Read More  

POMOC (2019)

Charles IV and the power of marvellous objects

Read More