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MyoChip SIGNED

Building a 3D innervated and irrigated muscle on a chip.

Total Cost €

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EC-Contrib. €

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Partnership

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Project "MyoChip" data sheet

The following table provides information about the project.

Coordinator
INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES 

Organization address
address: AVENIDA PROF EGAS MONIZ
city: LISBOA
postcode: 1649 028
website: www.imm.ul.pt

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Portugal [PT]
 Total cost 3˙153˙553 €
 EC max contribution 3˙153˙553 € (100%)
 Programme 1. H2020-EU.1.2.1. (FET Open)
 Code Call H2020-FETOPEN-1-2016-2017
 Funding Scheme RIA
 Starting year 2018
 Duration (year-month-day) from 2018-11-01   to  2022-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES PT (LISBOA) coordinator 1˙266˙861.00
2    INSTITUT CURIE FR (PARIS) participant 668˙054.00
3    THE UNIVERSITY OF EDINBURGH UK (EDINBURGH) participant 610˙172.00
4    FLUIGENT SA FR (LE KREMLIN-BICETRE) participant 608˙465.00

Map

 Project objective

The aim of the MyoChip project is to build a 3D human skeletal muscle irrigated by vasculature and innervated by neurons. The reconstituted 3D muscle will mirror the architecture and function found in vivo, namely in shape, contractility and microenvironment, while irrigation by a vascular network and innervation by human motor neurons will bring additional physiologic pertinence to it. This organ-on-a-chip technology will have numerous applications including but not limited to research on muscle building and aging, drug testing and screening, as well as prosthetics and biorobotics. The feasibility of the project relies on the interdisciplinary approach which joins a team of cell biologists, material engineers, experts in microfluidics and mathematical modellers. The architecture of skeletal muscle and its regenerative capabilities make muscle a prime candidate to push the 3D tissue engineering field. As such the project will lay the technical, material and methodological foundations to tackle the next generation of complex organ-on-a-chip systems that the MyoChip consortium can exploit for the generation of highly complex 3D in vitro systems of many organs.

 Deliverables

List of deliverables.
Data Management Plan Open Research Data Pilot 2020-02-12 16:55:13
Design of multi-tubular microchannels Demonstrators, pilots, prototypes 2020-02-12 16:55:23
Gene editing method Demonstrators, pilots, prototypes 2020-02-12 16:55:09
Project website and logo Websites, patent fillings, videos etc. 2020-02-12 16:55:12

Take a look to the deliverables list in detail:  detailed list of MyoChip deliverables.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "MYOCHIP" project.

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The information about "MYOCHIP" are provided by the European Opendata Portal: CORDIS opendata.

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