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PermeAbility SIGNED

PermeAbility - A non-invasive, side-effect-free diagnostic kit for intestinal disorders

Total Cost €

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EC-Contrib. €

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Partnership

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 PermeAbility project word cloud

Explore the words cloud of the PermeAbility project. It provides you a very rough idea of what is the project "PermeAbility" about.

disease    arthritis    acute    waste    wall    reinforced    lesions    stream    biopsy    leak    ulcers    obesity    burden    compromises    inflammation    indirect    decision    tightly    symptoms    clinical    threats    health    causes    rupture    reported    poses    toxic    35    gut    diagnosed    direct    structure    unnecessary    damage    dramatic    articles    connected    pain    permeability    though    disposing    restricted    rheumatoid    particles    digestion    clear    risk    mri    maintaining    diabetes    description    form    diarrhea    patients    abdominal    stool    bleedings    qualitative    proprietary    lgs    assessing    solely    intestinal    organization    select    causing    billion    urges    food    diagnosis    cells    diagnostic    limited    evaluation    intestine    extensive    worldwide    ibd    bowel    removal    quality    surgeries    people    facts    plasma    revealing    inflammatory    performed    economic    life    blood    microcapsule    syndrome    normally    lifetag    barrier    compromise    leaky    bacteria    markers    informed    heavy    invasive    treatment    small    besides    colonoscopy   

Project "PermeAbility" data sheet

The following table provides information about the project.

Coordinator
LIEFTAG LDA 

Organization address
address: BIOCANT - ASSOCIACAO DE TRANSFERENCIA DE TECNOLOGI
city: CANTANHEDE
postcode: 3060 197
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Portugal [PT]
 Project website https://lifetag.pt
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2018
 Duration (year-month-day) from 2018-08-01   to  2019-01-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    LIEFTAG LDA PT (CANTANHEDE) coordinator 50˙000.00

Map

 Project objective

'Inflammatory Bowel Disease (IBD) is a form of acute inflammation to the small intestine that causes ulcers and extensive damage of the gut barrier causing it to rupture. This causes bleedings, abdominal pain, diarrhea, and a dramatic reduction of the quality of life. The intestinal barrier is normally a very well organised structure in which the cells are tightly connected maintaining the barrier. Moreover, IBD lesions compromise this intestinal organization and increases intestinal permeability, which is called leaky gut syndrome (LGS) being also a pre-disposing factor for several other health problems. LGS compromises digestion of food particles and removal of toxic waste products, and allows bacteria to 'leak' through the intestine to the blood stream. Besides in IBD, LGS is also common in people with health conditions such as obesity, rheumatoid arthritis and type 2 diabetes. Even though IBD poses significant threats to a patients’ health and a heavy direct and indirect economic burden, diagnosis of this condition is still limited assessing indirect parameters like general inflammation markers in plasma and stool and evaluation based by comparison on the patients symptoms description. The direct measures are also performed but are restricted to very invasive methods like biopsy or solely qualitative like MRI and microcapsule colonoscopy. In this way it is reported in several clinical articles a clear need for new diagnostic methods in IBD reinforced by facts like 35% of the performed surgeries for treatment revealing unnecessary and 1.9 billion people worldwide at risk for early lesions and IBD development not being diagnosed. In this way clinical practice urges for new methods for the assessment of lesions in the intestinal wall. Lifetag’s has developed PermeAbility, a new proprietary test to measure intestinal permeability to better select patients at high risk of IBD , leading to better informed clinical decision making, diagnosis, and treatment.'

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The information about "PERMEABILITY" are provided by the European Opendata Portal: CORDIS opendata.

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