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EPIMARK SIGNED

Commercial feasibility of a kit for the identification of epigenetic markers in farmed fish

Total Cost €

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EC-Contrib. €

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Partnership

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Project "EPIMARK" data sheet

The following table provides information about the project.

Coordinator
NORD UNIVERSITET 

Organization address
address: UNIVERSITETSALLEEN 11
city: BODO
postcode: 8026
website: www.hibo.no

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Norway [NO]
 Total cost 149˙202 €
 EC max contribution 149˙202 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-PoC
 Funding Scheme ERC-POC
 Starting year 2018
 Duration (year-month-day) from 2018-09-01   to  2020-02-29

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    NORD UNIVERSITET NO (BODO) coordinator 149˙202.00

Map

 Project objective

Domestication and selective breeding of the major commercial fish species are essential to enable sustainability of the rapidly expanding aquaculture sector. The existing improvement programmes are based exclusively on genetic markers, overlooking the fact that selection for complex traits is strongly affected by environmental conditions and that epigenetics likely account for a large proportion of the observed phenotypic variation. Non-coding RNAs (e.g., miRNAs) and cytosine methylation (5mC) and hydroxymethylation (5hmC) of DNA are key mechanisms underlying epigenetic regulation of gene expression. We have recently identified a panel of 5mCs, 5hmCs and miRNAs that are potential epigenetic markers (epimarkers) of improved growth in Nile tilapia (Oreochromis niloticus). EPIMARK will evaluate the commercial feasibility of our novel kit of growth epimarkers, so that they can be applied in selective breeding programmes. This will be achieved by (i) validating the miRNA, 5mC and 5hmC epimarkers, (ii) developing an assay for their quantification, (iii) investigating the commercial and financial feasibility and (iv) developing the optimal business strategy, consolidated in a business plan. The EPIMARK kit will lead to a more efficient selection of fish in breeding programs based on growth potential, thereby increasing the profitability and sustainability of the aquaculture industry. The technology developed in EPIMARK will also open important avenues of innovation, including the use of epimarkers for selection of other superior production traits and disease resistance in Nile tilapia and in other species of commercial importance.

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The information about "EPIMARK" are provided by the European Opendata Portal: CORDIS opendata.

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