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GEMMA project deliverables

The page lists 9 deliverables related to the research project "GEMMA".

 List of Deliverables

GEMMA: list of downloadable deliverables.
title and desprition type last update

OmnomicsNGS v2 release

A new relase of the software OmnomicsNGS including a tool for dynamic variant analysis and interpretation

Programme: H2020-EU.3.1.2. - Topic(s): SC1-BHC-03-2018

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Demonstrators, pilots, prototypes 2020-04-25

Genome, epigenome and immune function interplay summary of hypothesis

An hypothesis regarding how the genome/metagenome interplay is responsible for the switch from immune tolerance to immune response to environmental stimuli (antigens) including dietary and microbial factors leading to neuroinflammation responsible of behavioural changes that characterize ASD and gut inflammation causing its GI co-morbidities

Programme: H2020-EU.3.1.2. - Topic(s): SC1-BHC-03-2018

download deliverable 

Documents, reports 2020-04-25

Pre-clinical study ethical approval report

A study protocol to submit for the approbation to the ethical committee

Programme: H2020-EU.3.1.2. - Topic(s): SC1-BHC-03-2018

download deliverable 

Documents, reports 2020-04-25

Updated state of the art report

Report providing a brief relation about the state of the art in the ASD biomarker and therapy

Programme: H2020-EU.3.1.2. - Topic(s): SC1-BHC-03-2018

download deliverable 

Documents, reports 2020-04-25

Microbiome, metabolome and immune function interplay summary of hypothesis

An hypothesis regarding how the gut bacterial dysbiosis leads to epigenetic modifications, changes in metabolic profiles, increased gut permeability, increased antigen trafficking and, ultimately to altered immune responses to promote disease in a subset of individuals at-risk of ASD

Programme: H2020-EU.3.1.2. - Topic(s): SC1-BHC-03-2018

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Documents, reports 2020-04-25

Pre-clinical study 3/1 report

A first report providing the results of trial 3 to establish whether correction of dysbiosis by pre/pro/symbiotic intervention prevents and/or treats increased the impaired gut permeability, changes in metabolic profile, modification of the immune response, and, ultimately, the onset of ASD behavioural symptoms in humanized murine models of ASD (mice transplanted with faecal bacterial content of ASD patient donor sample

Programme: H2020-EU.3.1.2. - Topic(s): SC1-BHC-03-2018

download deliverable 

Documents, reports 2020-04-25

External project website

Project website: project description, public deliverables, scientific news, other

Programme: H2020-EU.3.1.2. - Topic(s): SC1-BHC-03-2018

download deliverable 

Websites, patent fillings, videos etc. 2020-04-25

Final clinical protocols

Study protocols to submit for the approbation to the ethical committee

Programme: H2020-EU.3.1.2. - Topic(s): SC1-BHC-03-2018

download deliverable 

Documents, reports 2020-04-25

Open data management plan

GEMMA participation on H2020 open data pilot

Programme: H2020-EU.3.1.2. - Topic(s): SC1-BHC-03-2018

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Open Research Data Pilot 2020-04-25