Opendata, web and dolomites

3DBIOLUNG SIGNED

Bioengineering lung tissue using extracellular matrix based 3D bioprinting

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 3DBIOLUNG project word cloud

Explore the words cloud of the 3DBIOLUNG project. It provides you a very rough idea of what is the project "3DBIOLUNG" about.

vivo    ideally    models    immunosuppression    conductive    printed    lack    cells    obviating    synthetic    indicate    critical    awaiting    bioprint    sources    bioengineering    stage    3d    disease    functional    murine    area    engineering    mature    feasibility    diseases    tissue    differences    receive    prevalence    fiction    exchange    innovative    bioprinters    constructs    annually    xenogeneic    scalable    65    million    grown    demonstrating    thought    difficulty    science    ex    bioprinting    scaffolds    regeneration    chronic    angiogenesis    anatomical    transplant    primary    4000    seeded    biological    option    once    tissues    recipient    first    transplants    combining    1000    mimicking    cues    lung    patient    architecture    biologically    generating    immune    desperately    reproducibility    generate    reproducible    hybrid    manufacturing    bioreactor    materials    human    heterogeneity    custom    worldwide    gas    printing    options    patients    transplantation    prior    acellular   

Project "3DBIOLUNG" data sheet

The following table provides information about the project.

Coordinator
LUNDS UNIVERSITET 

Organization address
address: Paradisgatan 5c
city: LUND
postcode: 22100
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Total cost 1˙499˙975 €
 EC max contribution 1˙499˙975 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-STG
 Funding Scheme ERC-STG
 Starting year 2019
 Duration (year-month-day) from 2019-01-01   to  2023-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    LUNDS UNIVERSITET SE (LUND) coordinator 1˙499˙975.00

Map

 Project objective

Chronic lung diseases are increasing in prevalence with over 65 million patients worldwide. Lung transplantation remains the only potential option at end-stage disease. Around 4000 patients receive lung transplants annually with more awaiting transplantation, including 1000 patients in Europe. New options to increase available tissue for lung transplantation are desperately needed.

An exciting new research area focuses on generating lung tissue ex vivo using bioengineering approaches. Scaffolds can be generated from synthetic or biologically-derived (acellular) materials, seeded with cells and grown in a bioreactor prior to transplantation. Ideally, scaffolds would be seeded with cells derived from the transplant recipient, thus obviating the need for long-term immunosuppression. However, functional regeneration has yet to be achieved. New advances in 3D printing and 3D bioprinting (when cells are printed) indicate that this once thought of science-fiction concept might finally be mature enough for complex tissues, including lung. 3D bioprinting addresses a number of concerns identified in previous approaches, such as a) patient heterogeneity in acellular human scaffolds, b) anatomical differences in xenogeneic sources, c) lack of biological cues on synthetic materials and d) difficulty in manufacturing the complex lung architecture. 3D bioprinting could be a reproducible, scalable, and controllable approach for generating functional lung tissue.

The aim of this proposal is to use custom 3D bioprinters to generate constructs mimicking lung tissue using an innovative approach combining primary cells, the engineering reproducibility of synthetic materials, and the biologically conductive properties of acellular lung (hybrid). We will 3D bioprint hybrid murine and human lung tissue models and test gas exchange, angiogenesis and in vivo immune responses. This proposal will be a critical first step in demonstrating feasibility of 3D bioprinting lung tissue.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "3DBIOLUNG" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "3DBIOLUNG" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

ENUF (2019)

Evaluation of Novel Ultra-Fast selective III-V Epitaxy

Read More  

PonD (2019)

Particles-on-Demand for Multiscale Fluid Dynamics

Read More  

Aware (2019)

Aiding Antibiotic Development with Deep Analysis of Resistance Evolution

Read More