Opendata, web and dolomites


Bioengineering lung tissue using extracellular matrix based 3D bioprinting

Total Cost €


EC-Contrib. €






 3DBIOLUNG project word cloud

Explore the words cloud of the 3DBIOLUNG project. It provides you a very rough idea of what is the project "3DBIOLUNG" about.

functional    chronic    hybrid    tissues    scaffolds    gas    generate    immunosuppression    bioengineering    indicate    1000    transplant    area    patients    difficulty    tissue    diseases    differences    xenogeneic    thought    anatomical    primary    bioreactor    constructs    human    conductive    million    materials    reproducibility    scalable    manufacturing    desperately    engineering    custom    combining    sources    options    biologically    models    science    angiogenesis    transplantation    receive    printing    vivo    grown    exchange    regeneration    cues    prior    mature    heterogeneity    transplants    lack    ideally    immune    65    prevalence    printed    option    bioprinters    biological    bioprint    synthetic    innovative    seeded    first    annually    4000    reproducible    fiction    murine    demonstrating    3d    critical    disease    worldwide    lung    generating    obviating    acellular    architecture    awaiting    ex    patient    cells    stage    recipient    once    feasibility    bioprinting    mimicking   

Project "3DBIOLUNG" data sheet

The following table provides information about the project.


Organization address
address: Paradisgatan 5c
city: LUND
postcode: 22100
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Total cost 1˙499˙975 €
 EC max contribution 1˙499˙975 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-STG
 Funding Scheme ERC-STG
 Starting year 2019
 Duration (year-month-day) from 2019-01-01   to  2023-12-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    LUNDS UNIVERSITET SE (LUND) coordinator 1˙499˙975.00


 Project objective

Chronic lung diseases are increasing in prevalence with over 65 million patients worldwide. Lung transplantation remains the only potential option at end-stage disease. Around 4000 patients receive lung transplants annually with more awaiting transplantation, including 1000 patients in Europe. New options to increase available tissue for lung transplantation are desperately needed.

An exciting new research area focuses on generating lung tissue ex vivo using bioengineering approaches. Scaffolds can be generated from synthetic or biologically-derived (acellular) materials, seeded with cells and grown in a bioreactor prior to transplantation. Ideally, scaffolds would be seeded with cells derived from the transplant recipient, thus obviating the need for long-term immunosuppression. However, functional regeneration has yet to be achieved. New advances in 3D printing and 3D bioprinting (when cells are printed) indicate that this once thought of science-fiction concept might finally be mature enough for complex tissues, including lung. 3D bioprinting addresses a number of concerns identified in previous approaches, such as a) patient heterogeneity in acellular human scaffolds, b) anatomical differences in xenogeneic sources, c) lack of biological cues on synthetic materials and d) difficulty in manufacturing the complex lung architecture. 3D bioprinting could be a reproducible, scalable, and controllable approach for generating functional lung tissue.

The aim of this proposal is to use custom 3D bioprinters to generate constructs mimicking lung tissue using an innovative approach combining primary cells, the engineering reproducibility of synthetic materials, and the biologically conductive properties of acellular lung (hybrid). We will 3D bioprint hybrid murine and human lung tissue models and test gas exchange, angiogenesis and in vivo immune responses. This proposal will be a critical first step in demonstrating feasibility of 3D bioprinting lung tissue.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "3DBIOLUNG" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email ( and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "3DBIOLUNG" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

ECOLBEH (2020)

The Ecology of Collective Behaviour

Read More  

EVOMENS (2020)

The evolution of menstruation in primates

Read More  

NanoPD_P (2020)

High throughput multiplexed trace-analyte screening for diagnostics applications

Read More