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NextGen-O2k SIGNED

Next Generation Instrument for In-Depth Analysis of Mitochondrial Fitness

Total Cost €

EC-Contrib. €

Partnership

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NextGen-O2k project word cloud

Explore the words cloud of the NextGen-O2k project. It provides you a very rough idea of what is the project "NextGen-O2k" about.

technologies economy photosynthesis device complete mitochondria launch science funds prepare rate human biotech diagnosis compact bio generating limited experimental lacking market neurodegenerative optimization fitness diabetes mitochondrial nextgen therapeutic metabolite hindering biotechnology dysfunction bioenergetic exerted interventions diseases o2k crisis sensor affordable algal sustainable metabolism laboratory detecting monitoring medical segmented poor samples investigations function functional biomass implication pathologies inter reproducibility chloroplast tool chloroplasts time biomedicine bioenergetics cancer platform superior savings multiple millennia resolution cellular 2021 sensors

Project "NextGen-O2k" data sheet

The following table provides information about the project.

Coordinator	OROBOROS INSTRUMENTS GmbH Organization address address: SCHOPFSTRASSE 18 city: INNSBRUCK postcode: 6020 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Austria [AT]
Total cost	2˙357˙732 €
EC max contribution	1˙650˙412 € (70%)
Programme	1. H2020-EU.3. (PRIORITY 'Societal challenges) 2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs) 3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
Code Call	H2020-SMEInst-2018-2020-2
Funding Scheme	SME-2
Starting year	2019
Duration (year-month-day)	from 2019-06-01 to 2021-05-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	OROBOROS INSTRUMENTS GmbH OROBOROS INSTRUMENTS GmbH Organization address address: SCHOPFSTRASSE 18 city: INNSBRUCK postcode: 6020 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (INNSBRUCK)	coordinator	1˙650˙412.00

Map

Project objective

Mitochondria and chloroplasts are key elements to face the new challenges of the millennia for biomedicine, biotechnology and to develop a sustainable bio-economy. Mitochondrial fitness is a key parameter for diagnosis and therapeutic applications on multiple human pathologies, such as neurodegenerative diseases, diabetes and cancer. On the other hand, the optimization of algal growth rate and metabolite production in biotechnology requires novel investigations and monitoring of the bioenergetic pathway control exerted by mitochondria and chloroplasts. However, current technologies to study mitochondrial and chloroplast function are limited, providing segmented information, lacking inter-laboratory reproducibility and hindering our advance towards therapeutic and biotech interventions of cellular bioenergetics. As a result, the understanding of cellular bioenergetics for medical and algal biotechnology applications remains poor. The overall objective of this project is to complete the development of NextGen-O2k and prepare its market launch in 2021. NextGen-O2k is a multi-sensor platform for in-depth study of mitochondrial and chloroplast functional fitness. In a compact and affordable device, we have integrated several sensors for detecting multiple key parameters of bioenergetics, with superior resolution and reproducibility. With NextGen-O2k we will provide researchers with a tool able to improve knowledge about mitochondrial dysfunction and chloroplast photosynthesis, while bringing savings in experimental time, samples and funds. NextGen-O2k project is a step forward towards understanding mitochondrial implication in human pathologies and in the optimization of biomass production in many areas of biotechnology. Our focus in on generating knowledge about mitochondrial function and dysfunction, chloroplast photosynthesis and algal metabolism, while contributing to address the science reproducibility crisis.

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The information about "NEXTGEN-O2K" are provided by the European Opendata Portal: CORDIS opendata.