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EUROVA SIGNED

European Oocyte Biology Research Innovation Training Net

Total Cost €

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EC-Contrib. €

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Partnership

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Project "EUROVA" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN 

Organization address
address: BELFIELD
city: DUBLIN
postcode: 4
website: www.ucd.ie

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Ireland [IE]
 Total cost 3˙978˙647 €
 EC max contribution 3˙978˙647 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2019
 Funding Scheme MSCA-ITN-ETN
 Starting year 2019
 Duration (year-month-day) from 2019-11-01   to  2023-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN IE (DUBLIN) coordinator 549˙368.00
2    UNIVERSITA DEGLI STUDI DI MILANO IT (MILANO) participant 522˙999.00
3    UNIVERSITEIT GENT BE (GENT) participant 512˙640.00
4    VRIJE UNIVERSITEIT BRUSSEL BE (BRUSSEL) participant 512˙640.00
5    EUVITRO SLU ES (BARCELONA) participant 501˙809.00
6    THE BABRAHAM INSTITUTE UK (CAMBRIDGE) participant 303˙172.00
7    REGION HOVEDSTADEN DK (HILLEROD) participant 297˙522.00
8    CHERRY BIOTECH FR (RENNES) participant 274˙802.00
9    FORSCHUNGSVERBUND BERLIN EV DE (BERLIN) participant 252˙788.00
10    AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS ES (MADRID) participant 250˙904.00

Map

 Project objective

The hallmark of successful mammalian reproduction is the fusion between a haploid spermatozoon and a metaphase II oocyte. The generation of such an oocyte involves a series of steps whereby germinal-vesicle oocytes (in which the nuclei are intact) at prophase I are stimulated to resume meiosis and mature to metaphase II, a sequence of events that prepares the oocyte for fertilization. Although the treatment of infertility by Assisted Reproduction Technologies (ART) has been increasingly successful, the efficiency remains low with only about 1 in 10 eggs retrieved from women undergoing infertility treatments healthy enough to produce a pregnancy and birth. In healthy fertile livestock species, where ARTs are applied for production purposes this number increases to 1 in 6 eggs retrieved, which is still remarkably inefficient. The greatest block to advancement, is the substantial lack of knowledge on the key regulatory checkpoints and processes that determine oocyte health. Such knowledge is key not just to treating infertility and maximising livestock genetic potential and productivity, but also to the field of regenerative medicine, where the reprogramming potential of the oocyte cytoplasm is critical to reprogramming somatic genomes. The EUROVA ETN will train a consolidate European Oocyte Biology Research, train a new cohort of Reproductive scientists and generate new knowledge. A deeper knowledge and understanding of the mechanisms set in place during the trajectory of oocyte growth, maturation, fertilization and oocyte to zygote transition will lead to innovations in ART, animal breeding, endangered species preservation, regenerative medicine and reproductive toxicology.

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The information about "EUROVA" are provided by the European Opendata Portal: CORDIS opendata.

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