Opendata, web and dolomites

ii-MAX SIGNED

Unravelling new immunity-independent mechanisms for durable resistance to blast fungi using MAX effectors

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

Project "ii-MAX" data sheet

The following table provides information about the project.

Coordinator
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT 

Organization address
address: Rue De L'Universite 147
city: PARIS CEDEX 07
postcode: 75338
website: www.inra.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 1˙499˙875 €
 EC max contribution 1˙499˙875 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2019-STG
 Funding Scheme ERC-STG
 Starting year 2020
 Duration (year-month-day) from 2020-04-01   to  2025-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT FR (PARIS CEDEX 07) coordinator 1˙499˙875.00

Map

 Project objective

As staple food crops, cereals are essential to feed the world’s growing population. Keeping pace with demography and global change requires increasing cereal yields in a sustainable manner. Destructive fungal pathogens such as Magnaporthe oryzae, the causal agent of the blast disease, represent major threats to cereal production. In this context, the ii-MAX project will produce ground-breaking knowledge of fungal virulence and plant immunity that will be valuable to engineer durable resistance to blast in cereals. During plant infection, pathogens deploy molecular weapons known as effectors that target cellular processes of the host to promote infection. In M. oryzae, a particularly large and diverse family of effectors has recently been discovered: the MAX (Magnaporthe AVRs and ToxB-like) effector family. Remarkably, these effectors possess various protein sequences but exhibit a conserved structure. The MAX effector family is specific to ascomycete fungi but has undergone massive expansion in M. oryzae suggesting a primary role for these effectors in the infectious process. Nonetheless, the cellular mechanisms they target in cereals are largely unknown. The aim of my project is to identify the host proteins targeted by M. oryzae MAX effectors and conduct a comprehensive study of the biophysical and functional interactions between MAX effectors and their target proteins in rice. This will enable new sources of resistance to be developed by modifying host susceptibility proteins targeted by MAX effectors. To achieve this goal, I defined four objectives: 1-Identify the host proteins targeted by MAX effectors. 2-Define the structural and biophysical properties governing the interaction of MAX effectors with their virulence targets in cereals. 3-Improve resistance to blast in rice by mutating virulence targets of MAX effectors required for susceptibility to M. oryzae. 4-Elucidate the virulence function of MAX effectors through functional investigation of their targets.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "II-MAX" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "II-MAX" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

HyperBio (2019)

Vis-NIR Hyperspectral imaging for biomaterial quality control

Read More  

AllergenDetect (2019)

Comprehensive allergen detection using synthetic DNA libraries

Read More  

DISINTEGRATION (2019)

The Mass Politics of Disintegration

Read More