Opendata, web and dolomites


Investigation into the Molecular Mechanisms Underlying NEmatode recognition by the Ma resistance protein in perennial plum roots

Total Cost €


EC-Contrib. €






 IMMUNE project word cloud

Explore the words cloud of the IMMUNE project. It provides you a very rough idea of what is the project "IMMUNE" about.

mediated    repeat    plant    extention    function    root    recognition    prunus    terminal    immunity    nb    meloidogyne    pl    receptor    roots    repeated    participates    knot    rkns    resistance    huge    inra    biological    cerasifera    predominant    undertaken    cloned    isa    tree    ma    single    perennial    species    disease    broad    rkn    combining    involvement    decipher    banned    parasitic    global    infection    classes    architecture    causing    binding    domain    rely    losses    pathogens    spp    dr    gene    carries    absence    mainly    nematodes    describe    toll    mechanisms    tnl    receptors    simon    peculiar    encoding    saucet    pesticides    worldwide    suggests    post    nucleotide    toxic    conservation    provides    resistant    opportunity    interleukin    threat    agrobiotech    detection    unknown    insights    tnls    plum    annual    triggers    layered    found    drastically    crops    complementary    immune    leucine    molecular    susceptible    alternative    interestingly    exons    crop    innate    tir    network    resides    signalling    family    lrr    sophia    copy   

Project "IMMUNE" data sheet

The following table provides information about the project.


Organization address
address: Rue De L'Universite 147
city: PARIS CEDEX 07
postcode: 75338

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 184˙707 €
 EC max contribution 184˙707 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-RI
 Starting year 2019
 Duration (year-month-day) from 2019-11-15   to  2021-11-14


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

Plant-parasitic nematodes are major root pathogens that affect drastically plant development and growth. Predominant species, such as the root-knot nematodes (RKNs) Meloidogyne spp., represent a global threat for annual and perennial crops causing huge crop losses worldwide. In Europe, RKNs were mainly controlled by toxic pesticides that are getting banned. One of the most promising alternative to pesticides is to rely on biological control and on the plant innate immunity for disease resistance in crops. The plant immune system is a multi-layered network that enables the detection of pathogens using different classes of receptors. The presence/absence of such receptor can determine whether or not the plant will be resistant/susceptible to a particular disease. At INRA Sophia Agrobiotech Institute (ISA), an immune receptor gene Ma, from the toll/interleukin-1 receptor, nucleotide-binding and leucine-rich repeat (TIR-NB-LRR or TNL) family, has been cloned from the plum tree Prunus cerasifera where it provides a broad resistance against numerous RKN species. A unique feature of Ma resides in five repeated exons encoding a large C-terminal extention. Interestingly, each of those exons carries a recently characterized post-LRR (PL) domain which is found in a single copy in many other TNLs from different plant species. The PL domain’s function remains unknown but its conservation suggests an important role in TNLs. The peculiar architecture of Ma provides a great opportunity to decipher the involvement of the PL domain in TNL–mediated immunity. Combining complementary approaches, the proposed IMMUNE project aims to describe how Ma triggers immunity in response to RKNs in plant roots and how the PL domain participates in the recognition and signalling. This project, undertaken by Dr Simon Saucet at ISA, will provide new insights into the molecular mechanisms of plant immunity and contribute to the development of methods to control RKNs infection in crops.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "IMMUNE" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email ( and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "IMMUNE" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

NeoPur (2019)

New treatments and novel diagnostic tests for neonatal seizures based on purinergic signaling.

Read More  

BirthControlEnvirons (2019)

Contraception meets the environment: everyday contraceptive practices, politics, and futures in a toxic age

Read More  

FOCUSIS (2020)

Focal volume Control Using Structured Illumination Sources

Read More