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CAESAR SIGNED

Developing Therapeutic Antibodies for Pets

Total Cost €

EC-Contrib. €

Partnership

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CAESAR project word cloud

Explore the words cloud of the CAESAR project. It provides you a very rough idea of what is the project "CAESAR" about.

emotional veterinary licensing companion owners launch managed 6 adivo therapeutic suffering demonstrated therapy pet expensive species gt 15m first complete native canine 5k generating cancer overcome dogs antibodies pay founded solution ge distress affordable health 3k animal library reliance severe people demographic team diseases medicine poorly royalties 2016 generate revenue synthetic 400 german phage 40 shifts relieve 12 expanding ownership ibd treat inflammation 2million company inflammatory causing synthesize spend specializing 2018 worth therapeutics chronic ease display scalable companions medical bowel animals pets untenable hire cagr therapies human caesar antibody biotech causes ineffective put global immunogenic 29bn market financial sufficiently

Project "CAESAR" data sheet

The following table provides information about the project.

Coordinator	ADIVO GMBH Organization address address: AM KLOPFERSPITZ 19 city: PLANEGG postcode: 82152 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Germany [DE]
Total cost	71˙429 €
EC max contribution	50˙000 € (70%)
Programme	1. H2020-EU.3. (PRIORITY 'Societal challenges) 2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs) 3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
Code Call	H2020-SMEInst-2018-2020-1
Funding Scheme	SME-1
Starting year	2019
Duration (year-month-day)	from 2019-11-01 to 2020-04-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	ADIVO GMBH ADIVO GMBH Organization address address: AM KLOPFERSPITZ 19 city: PLANEGG postcode: 82152 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (PLANEGG)	coordinator	50˙000.00

Map

Project objective

Chronic inflammatory diseases in pets such as Inflammatory Bowel Diseases (IBD) are poorly managed causing emotional and financial distress to pet owners. Current therapies are ineffective - they do not relieve pet suffering and lead to the animal being put down. Therapies are also expensive with costs up to €400/month. Antibody therapy for such conditions has long been used in human medicine but has not been sufficiently developed for veterinary medicine and causes an immunogenic response as the antibodies are not species specific. Antibodies need to be adapted which is expensive and causes severe side effects making them an untenable solution at present. Pet ownership in the EU has been on the increase (up by 2million pets since 2016) due to demographic shifts and a greater reliance on pets as companions. The global animal health market is worth > €29Bn growing at a CAGR of 6% with pet health making up 40% of the market. Pet owners spend €3k - €5k/ year on their pet’s health and are willing to pay to ease pet suffering. adivo is a German biotech company specializing in generating species-specific therapeutic antibodies for companion animals. adivo was founded in 2018. The adivo-team aims to address medical needs in dogs including cancer and chronic inflammation, with the potential of expanding activities into the development of therapeutics for other species in future. adivo has developed CAESAR, the first of a kind synthetic canine phage-display library to generate therapeutic antibodies for dogs. We have developed a complete library from which we can synthesize therapeutic antibodies native to treat IBD. Our solution will overcome the challenges of current therapies and provide an affordable, scalable solution for effective antibody therapy for pets which has been demonstrated in human medicine. We expect to generate out-licensing revenue ≥€15M when we launch the product before royalties and hire 12 people.

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The information about "CAESAR" are provided by the European Opendata Portal: CORDIS opendata.