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CAESAR SIGNED

Developing Therapeutic Antibodies for Pets

Total Cost €

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EC-Contrib. €

0

Partnership

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 CAESAR project word cloud

Explore the words cloud of the CAESAR project. It provides you a very rough idea of what is the project "CAESAR" about.

medical    ge    immunogenic    put    antibodies    severe    library    generating    first    royalties    company    therapeutic    affordable    untenable    reliance    sufficiently    companions    demonstrated    adivo    therapeutics    ease    emotional    treat    distress    health    managed    team    ownership    native    29bn    expensive    financial    2016    causes    dogs    canine    40    therapy    medicine    5k    relieve    ineffective    caesar    display    generate    400    worth    therapies    cancer    chronic    pay    human    solution    demographic    companion    synthetic    diseases    market    synthesize    inflammatory    owners    2million    revenue    german    3k    animals    antibody    pets    causing    veterinary    scalable    overcome    founded    inflammation    cagr    pet    ibd    bowel    spend       suffering    licensing    2018    specializing    gt    animal    12    expanding    15m    global    shifts    people    phage    hire    complete    poorly    biotech    species    launch   

Project "CAESAR" data sheet

The following table provides information about the project.

Coordinator
ADIVO GMBH 

Organization address
address: AM KLOPFERSPITZ 19
city: PLANEGG
postcode: 82152
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-11-01   to  2020-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ADIVO GMBH DE (PLANEGG) coordinator 50˙000.00

Map

 Project objective

Chronic inflammatory diseases in pets such as Inflammatory Bowel Diseases (IBD) are poorly managed causing emotional and financial distress to pet owners. Current therapies are ineffective - they do not relieve pet suffering and lead to the animal being put down. Therapies are also expensive with costs up to €400/month. Antibody therapy for such conditions has long been used in human medicine but has not been sufficiently developed for veterinary medicine and causes an immunogenic response as the antibodies are not species specific. Antibodies need to be adapted which is expensive and causes severe side effects making them an untenable solution at present. Pet ownership in the EU has been on the increase (up by 2million pets since 2016) due to demographic shifts and a greater reliance on pets as companions. The global animal health market is worth > €29Bn growing at a CAGR of 6% with pet health making up 40% of the market. Pet owners spend €3k - €5k/ year on their pet’s health and are willing to pay to ease pet suffering. adivo is a German biotech company specializing in generating species-specific therapeutic antibodies for companion animals. adivo was founded in 2018. The adivo-team aims to address medical needs in dogs including cancer and chronic inflammation, with the potential of expanding activities into the development of therapeutics for other species in future. adivo has developed CAESAR, the first of a kind synthetic canine phage-display library to generate therapeutic antibodies for dogs. We have developed a complete library from which we can synthesize therapeutic antibodies native to treat IBD. Our solution will overcome the challenges of current therapies and provide an affordable, scalable solution for effective antibody therapy for pets which has been demonstrated in human medicine. We expect to generate out-licensing revenue ≥€15M when we launch the product before royalties and hire 12 people.

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The information about "CAESAR" are provided by the European Opendata Portal: CORDIS opendata.

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