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CUBE SIGNED

Unravelling the secrets of Cu-based catalysts for C-H activation

Total Cost €

EC-Contrib. €

Partnership

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CUBE project word cloud

Explore the words cloud of the CUBE project. It provides you a very rough idea of what is the project "CUBE" about.

pursued capitalize conceived frameworks players complementary gap rationally scarce interface plan center heterogeneous selective engineering o2 evolve catalysts n2o bridge cu abundant biological vigorously mofs zeolites protein fertilization catalyst elucidate catalysis catalytic activation activate generate cross flexibility h2o2 discovery progress containing trans hybrid grail homogeneous synthetic organic insights maximize activating designed synthesis brings metal uio engineered unprecedented nmbu investigations acquired synergistically spectroscopy mpi mechanistic polymer mono principles selectivity uot team enzymology cube secrets accessible bonds chemistry materials harness translating turn spectroscopic natural lpmos efforts oxidant holy disclosing enzyme resilient disciplinary experimentally enzymes computational tomorrow zr

Project "CUBE" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITETET I OSLO Organization address address: PROBLEMVEIEN 5-7 city: OSLO postcode: 313 website: www.uio.no contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Norway [NO]
Total cost	9˙885˙989 €
EC max contribution	9˙885˙988 € (100%)
Programme	1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
Code Call	ERC-2019-SyG
Funding Scheme	ERC-SyG
Starting year	2020
Duration (year-month-day)	from 2020-04-01 to 2026-03-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITETET I OSLO UNIVERSITETET I OSLO Organization address address: PROBLEMVEIEN 5-7 city: OSLO postcode: 313 website: www.uio.no contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NO (OSLO)	coordinator	2˙906˙039.00
2	NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET Organization address address: UNIVERSITETSTUNET 3 city: AS postcode: 1433 website: http://www.nmbu.no contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NO (AS)	participant	2˙796˙408.00
3	MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV Organization address address: HOFGARTENSTRASSE 8 city: MUENCHEN postcode: 80539 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (MUENCHEN)	participant	2˙103˙750.00
4	UNIVERSITA DEGLI STUDI DI TORINO UNIVERSITA DEGLI STUDI DI TORINO Organization address address: VIA GIUSEPPE VERDI 8 city: TORINO postcode: 10124 website: www.unito.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (TORINO)	participant	2˙079˙791.00

Map

Project objective

The Holy Grail of selective C-H activation has been vigorously pursued for more than 70 years in all areas of catalysis - homogeneous, heterogeneous and biological - yet with scarce cross-fertilization. CUBE will bridge this gap, by synergistically disclosing the secrets of Cu-containing biological and synthetic catalysts and translating the acquired knowledge into rationally designed new catalysts with unprecedented activity, selectivity and turn-over numbers. CUBE will capitalize on the recent discovery of abundant and experimentally accessible natural enzymes (LPMOs) that activate resilient C-H bonds using a mono-Cu catalytic center, thus providing a biological analogue to synthetic Cu-zeolites. CUBE will also harness the potential of metal-organic frameworks (MOFs), which offer unprecedented (“enzyme-like”) flexibility in catalyst development. C-H activating Cu-containing Zr-MOFs have just been described. CUBE will generate trans-disciplinary insights into Cu-based catalysts to progress beyond the state of the art in C-H activation. To this aim, we will elucidate the key mechanistic features of oxidant activation by O2, as well as N2O and H2O2, and then C-H activation. Emerging design principles from these studies will evolve new catalysts, including engineered enzymes, enzyme-polymer hybrid materials, and MOFs. To enable these efforts, we will develop novel methodologies at the interface of spectroscopy and computational chemistry. The project brings together leading players in complementary fields: design, synthesis and testing of catalysts (UiO), enzymology and protein engineering (NMBU), spectroscopic investigations of heterogeneous catalysts (UoT) and spectroscopic/computational studies of homogeneous and biological catalysts (MPI). Through a work-plan conceived to maximize cross-fertilization within the project team, we will design and develop novel catalysts for tomorrow’s C-H activation chemistry.

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The information about "CUBE" are provided by the European Opendata Portal: CORDIS opendata.