ARTIVASC 3D
Artificial vascularised scaffolds for 3D-tissue-regeneration
| Coordinatore | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V
Organization address
address: Hansastrasse 27C contact info |
| Nazionalità Coordinatore | Germany [DE] |
| Totale costo | 10˙467˙338 € |
| EC contributo | 7˙800˙000 € |
| Programma | FP7-NMP
Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies |
| Code Call | FP7-NMP-2010-LARGE-4 |
| Funding Scheme | CP-IP |
| Anno di inizio | 2011 |
| Periodo (anno-mese-giorno) | 2011-11-01 - 2015-10-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V
Organization address
address: Hansastrasse 27C contact info |
DE (MUENCHEN) | coordinator | 2˙207˙375.00 |
| 2 |
UNITECHNOLOGIES SA
Organization address
address: Route de Berne 5 contact info |
CH (Gals) | participant | 528˙562.00 |
| 3 |
VEREIN ZUR FORDERUNG VON INNOVATIONEN DURCH FORSCHUNG ENTWICKLUNG UNDTECHNOLOGIETRANSFER EV
Organization address
address: PRUESSINGSTRASSE 27B contact info |
DE (JENA) | participant | 499˙316.00 |
| 4 |
UNIVERSITY OF EAST ANGLIA
Organization address
address: EARLHAM ROAD contact info |
UK (NORWICH) | participant | 461˙029.00 |
| 5 |
AALTO-KORKEAKOULUSAATIO
Organization address
address: OTAKAARI 1 contact info |
FI (ESPOO) | participant | 444˙729.80 |
| 6 |
BERUFSGENOSSENSCHAFLICHES UNIVERSITAETSKLINIKUM BERGMANNSHEIL GMBH
Organization address
address: BUERKLE-DE-LA-CAMP-PLATZ 1 contact info |
DE (BOCHUM) | participant | 444˙317.00 |
| 7 |
MEDIZINISCHE UNIVERSITAET WIEN
Organization address
address: SPITALGASSE 23 contact info |
AT (WIEN) | participant | 426˙607.00 |
| 8 |
UNIVERSITAET STUTTGART
Organization address
address: Keplerstrasse 7 contact info |
DE (STUTTGART) | participant | 419˙739.60 |
| 9 |
ARTTIC
Organization address
address: Rue du Dessous des Berges 58A contact info |
FR (PARIS) | participant | 377˙632.00 |
| 10 |
KMS Automation GmbH
Organization address
address: Im Webertal 20 contact info |
DE (Schramberg-Waldmoesssingen) | participant | 374˙999.00 |
| 11 |
UNIVERSITA DEGLI STUDI DI SALERNO
Organization address
address: VIA GIOVANNI PAOLO II 132 contact info |
IT (FISCIANO (SA)) | participant | 374˙998.80 |
| 12 |
BEIERSDORF AG
Organization address
address: UNNASTRASSE 48 contact info |
DE (HAMBURG) | participant | 363˙678.00 |
| 13 |
LOUGHBOROUGH UNIVERSITY
Organization address
address: Ashby Road contact info |
UK (LOUGHBOROUGH) | participant | 328˙876.80 |
| 14 |
ALBERT-LUDWIGS-UNIVERSITAET FREIBURG
Organization address
address: FAHNENBERGPLATZ contact info |
DE (FREIBURG) | participant | 309˙779.00 |
| 15 |
VIMECON GMBH
Organization address
address: KAISERSTRASSE 100 contact info |
DE (HERZOGENRATH) | participant | 148˙307.00 |
| 16 |
AO-FORSCHUNGSINSTITUT DAVOS
Organization address
address: Clavadelerstrasse 8 contact info |
CH (Davos Platz) | participant | 90˙054.00 |
| 17 |
GLOBAL CLINICAL TRIALS MANAGEMENT AG
Organization address
address: GRABENSTRASSE 15 contact info |
CH (CHUR) | participant | 0.00 |
Mappa
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Obiettivo del progetto (Objective)
'The use of bioartificial tissue for regenerative medicine offers great therapeutic potential, but also has to meet high demands with respect to the interaction of the bioartificial devices and natural tissues. Key issues for the successful use of bioartifical tissues as natural tissue replacements are their long term functional stability and biocompatible integration. Up to now, various approaches for the generation of bioartificial tissues have not succeeded due to insufficient nutrition and oxygen supply. Therefore, current tissue engineered products have only been realised for non vascularised tissues such as cartilage. ArtiVasc 3D will break new ground and overcome these challenges by providing a micro- and nano-scale based manufacturing and functionalisation technology for the generation of fully vascularised bioartificial tissue that enables entire nutrition and metabolism. The bioartificial vascularised skin engineered in ArtiVasc 3D will, for the first time, allow tissue replacement with optimum properties. ArtiVasc 3D will research and develop an innovative combination of hi-tech engineering such as micro-scale printing, nano-scale multiphoton polymerisation and electro-spinning with biological research on biochemical surface modification and complex cell culture. In a multidisciplinary approach, experts in biomaterial development, cell-matrix interaction, angiogenesis, tissue engineering, simulation, design and fabrication methods work together to generate bioartificial vascularised skin in a fully automated and standardised manufacturing approach. This bioartificial vascularised skin will be of great value in a vast array of clinical treatments, e.g. as a transplant in trauma treatment. In addition, this new bioartificial vascularised skin will be used as an innovative in vitro skin equivalent for pharmaceutical, cosmetics or chemical substance testing, which represents a promising method to reduce expensive, ethically disputed animal testing.'
Introduzione (Teaser)
Bio-artificial soft tissue can be used to treat burns and wounds as well as reduce animal testing in cosmetics and chemicals. However, integration of thicker tissues has not been successful due to insufficient nutrition and oxygen supply from poor vascularisation.
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