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ANCHOR
Articular cartilage regeneration through the recruitment of bone marrow derived mesenchymal stem cells into extracelluar matrix derived scaffolds anchored by 3D printed polymeric supports
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0ANCHOR project word cloud
Explore the words cloud of the ANCHOR project. It provides you a very rough idea of what is the project "ANCHOR" about.
surgical
form
ecm
inductivity
reducing
commercial
transform
dramatically
disease
synovial
medicinal
lines
recruits
commercialise
printed
cells
maximise
matrix
create
leverage
endogenous
technically
complexity
inherent
hyaline
scaffold
stem
marrow
bone
subchondral
seeding
supports
consuming
suturing
cartilage
prior
regeneration
anchored
polymeric
serious
patient
articular
anchor
implantation
oa
osteoarthritis
obviate
recruiting
population
10
prohibitively
chondro
economic
surgeons
extensive
ineffective
arthritis
biomaterials
damaged
defects
time
thereby
nearly
health
extracellular
faceted
repair
treat
scaffolds
supporting
procedure
worldwide
ip
3d
applicants
bones
joints
strategies
onset
overcome
defect
orthopaedic
printing
expensive
commercialization
Project "ANCHOR" data sheet
The following table provides information about the project.
| Coordinator |
THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Organization address contact info |
| Coordinator Country | Ireland [IE] |
| Total cost | 149˙945 € |
| EC max contribution | 149˙945 € (100%) |
| Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
| Code Call | ERC-2017-PoC |
| Funding Scheme | ERC-POC |
| Starting year | 2018 |
| Duration (year-month-day) | from 2018-01-01 to 2019-06-30 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN | IE (DUBLIN) | coordinator | 124˙945.00 |
| 2 | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN | IE (DUBLIN) | participant | 25˙000.00 |
Map
Project objective
Osteoarthritis (OA), the most common form of arthritis, is a serious disease of the joints affecting nearly 10% of the population worldwide. The onset of OA has been associated with defects to articular cartilage that lines the bones of synovial joints. Current strategies to treat articular cartilage defects are ineffective and/or prohibitively expensive. The aim of ANCHOR is to develop and commercialise a new medicinal product for articular cartilage regeneration that recruits endogenous bone marrow derived stem cells into an extracellular matrix derived scaffold anchored to the subchondral bone by 3D printed polymeric supports. By recruiting endogenous cells into a supporting scaffold, ANCHOR will obviate the need for pre-seeding scaffolds with cells prior to implantation into cartilage defects, thereby dramatically reducing the cost and complexity of the repair procedure. It will also overcome the need for suturing of a scaffold into a cartilage defect, which is a very time consuming and technically challenging surgical procedure. Finally, the inherent chondro-inductivity of the cartilage ECM derived scaffolds developed by the applicant will maximise the potential for hyaline cartilage regeneration. The project will leverage the applicants extensive experience in ECM derived biomaterials and 3D printing to develop a new product with significant commercial potential. The impact of ANCHOR will be multi-faceted: it will transform how damaged joints are treated by orthopaedic surgeons, it will create economic value through the commercialization of IP, and most importantly it will improve patient experience and their long-term health and well-being.
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The information about "ANCHOR" are provided by the European Opendata Portal: CORDIS opendata.
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lastchecktime (2024-05-15 2:46:28) correctly updated