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MULTI-APP

Multivalent Molecular Systems for Innovative Applications

Total Cost €

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EC-Contrib. €

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Partnership

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Project "MULTI-APP" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITA DEGLI STUDI DI PADOVA 

Organization address
address: VIA 8 FEBBRAIO 2
city: PADOVA
postcode: 35122
website: www.unipd.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website http://www.multi-app.eu
 Total cost 2˙321˙096 €
 EC max contribution 2˙321˙096 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2014
 Funding Scheme MSCA-ITN-ETN
 Starting year 2015
 Duration (year-month-day) from 2015-01-01   to  2018-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITA DEGLI STUDI DI PADOVA IT (PADOVA) coordinator 516˙122.00
2    FREIE UNIVERSITAET BERLIN DE (BERLIN) participant 498˙432.00
3    THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE UK (CAMBRIDGE) participant 273˙287.00
4    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD UK (OXFORD) participant 273˙287.00
5    TECHNISCHE UNIVERSITEIT EINDHOVEN NL (EINDHOVEN) participant 255˙374.00
6    UNIVERSITEIT TWENTE NL (ENSCHEDE) participant 255˙374.00
7    WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER DE (MUENSTER) participant 249˙216.00
8    mivenion GmbH DE (Berlin) partner 0.00
9    PHILIPS ELECTRONICS NEDERLAND BV NL (EINDHOVEN) partner 0.00

Map

 Project objective

This network brings together the major academic players active in Europe on the fundamentals and application of multivalency and cooperativity. The network is complemented by industrial partners ranging in scale from a small spin-off to a large multinational. The main objective of this consortium is to raise a new generation of researchers able to develop complex chemical systems that harness cooperativity for enhanced functional properties. Multivalency is one of Nature’s governing principles for achieving strong and selective biomolecular recognition. Many biological processes rely on the cooperative effects associated with the occurrence of multivalent interactions. Consequently, there is an enormous interest in the development of chemical multivalent systems that display similar features for innovative applications in fields as various as diagnostics, drug discovery, materials science and nanotechnology. The central theme of multivalency and cooperativity is used to connect partners from academia and industry with a common interest in understanding how multivalency works, but for very different scopes and using very different approaches. This network is thus uniquely positioned to train the next generation of European researchers in all multidisciplinary aspects related to multivalency. A broad training program has been developed that comprises top-level individual research projects, both general and specific network-wide dedicated courses, secondments, personalized scientific training and a broad package of complementary skill training. The industrial partners contribute in the form of training, supervision, technical contributions, and perspectives on the commercialisation of multivalent systems. After completion of the program, the ESRs will be the first generation of researchers able to fully exploit the potential of multivalent chemical systems. Their unrivalled career profiles will enable them to compete successfully for positions in academia or industry.

 Deliverables

List of deliverables.
Sensing system for bio-analytes based on nanoparticle assembly Other 2019-09-02 09:20:12
Photoresponsive nanosystem Other 2019-09-02 09:20:12
Magnetic aggregates with controlled shape Other 2019-09-02 09:20:12
Magnetic hydrogels Other 2019-09-02 09:20:12
Modular assay for small molecules and metal ions Other 2019-09-02 09:20:12
Sensing system for bio-analytes based on clustered demixing Other 2019-09-02 09:20:12
Multivalent sensing system for biodiagnostics Other 2019-09-02 09:20:12
Multivalent dye block copolymer conjugates for cellular imaging Other 2019-09-02 09:20:12
Theoretical framework for describing cooperativity in complex systems Other 2019-09-02 09:20:12
Theoretical model for the quantitative prediction of chelate cooperativity Other 2019-09-02 09:20:12
Supervisory Board of the network Other 2019-09-02 09:20:11
Mid-term meeting Other 2019-09-02 09:20:11
Progress Report Documents, reports 2019-09-02 09:20:11
Website Websites, patent fillings, videos etc. 2019-09-02 09:20:12
Draft Periodic Report Documents, reports 2019-09-02 09:20:11

Take a look to the deliverables list in detail:  detailed list of MULTI-APP deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Miguel Ángel Alemán García, Eva Magdalena Estirado, Lech-Gustav Milroy, Luc Brunsveld
Dual-Input Regulation and Positional Control in Hybrid Oligonucleotide/Discotic Supramolecular Wires
published pages: 4976-4980, ISSN: 1433-7851, DOI: 10.1002/anie.201800148
Angewandte Chemie International Edition 57/18 2019-10-29
2018 Pallavi Kiran, Sumati Bhatia, Daniel Lauster, Stevan Aleksić, Carsten Fleck, Natalija Peric, Wolfgang Maison, Susanne Liese, Bettina G. Keller, Andreas Herrmann, Rainer Haag
Exploring Rigid and Flexible Core Trivalent Sialosides for Influenza Virus Inhibition
published pages: 19373-19385, ISSN: 0947-6539, DOI: 10.1002/chem.201804826
Chemistry - A European Journal 24/72 2019-10-29
2017 Remco Arts, Susann K. J. Ludwig, Benice C. B. van Gerven, Eva Magdalena Estirado, Lech-Gustav Milroy, Maarten Merkx
Semisynthetic Bioluminescent Sensor Proteins for Direct Detection of Antibodies and Small Molecules in Solution
published pages: 1730-1736, ISSN: 2379-3694, DOI: 10.1021/acssensors.7b00695
ACS Sensors 2/11 2019-10-08
2017 Michel Rickhaus, Andreas Vargas Jentzsch, Lara Tejerina, Isabell Grübner, Michael Jirasek, Timothy D. W. Claridge, Harry L. Anderson
Single-Acetylene Linked Porphyrin Nanorings
published pages: 16502-16505, ISSN: 0002-7863, DOI: 10.1021/jacs.7b10710
Journal of the American Chemical Society 139/46 2019-10-08
2017 Chih-Wei Chu, Bart Jan Ravoo
Hierarchical supramolecular hydrogels: self-assembly by peptides and photo-controlled release via host–guest interaction
published pages: 12450-12453, ISSN: 1359-7345, DOI: 10.1039/c7cc07859e
Chemical Communications 53/92 2019-10-08
2016 P. Motloch, C.A. Hunter
Thermodynamic Effective Molarities for Supramolecular Complexes
published pages: 77-118, ISSN: , DOI: 10.1016/bs.apoc.2016.07.001
Advances in Physical Organic Chemistry 2019-09-02

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The information about "MULTI-APP" are provided by the European Opendata Portal: CORDIS opendata.

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