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DURETO

Rearm cultivated tomato with natural and durable resistance mechanisms from wild tomato species

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 DURETO project word cloud

Explore the words cloud of the DURETO project. It provides you a very rough idea of what is the project "DURETO" about.

repellent    insect    species    pesticides    material    incorporation    neonicotinoids    transcriptional    rnas    follow    threat    molecular    mechanisms    post    collection    seem    genomic    mapping    led    cultivated    extensive    phenotypes    associate    insects    shown    markers    natural    insecticides    environments    industry    toxic    messenger    small    compare    themselves    sequence    govern    tomatoes    corresponding    commercially    biology    hairs    resistance    producing    leaf    tomato    regulations    quantitatively    defence    compounds    bioinformatics    stem    phenotypic    re    glandular    enhanced    epizingiberene    discover    effect    transcripts    researcher    consequently    me    data    combining    surface    regulatory    successful    gaining    biosynthetic    defend    metabolic    plant    introduction    previously    terpene    biostatistics    stored    regulation    wild    vegetable    background    accessions    independent    trichomes    breeding    protected    translated    polymorphisms    banned    genomes   

Project "DURETO" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITEIT VAN AMSTERDAM 

Organization address
address: SPUI 21
city: AMSTERDAM
postcode: 1012WX
website: www.uva.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Project website http://gls.uva.nl/profile/b/l/p.m.bleeker/p.m.bleeker.html
 Total cost 165˙598 €
 EC max contribution 165˙598 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-05-01   to  2017-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITEIT VAN AMSTERDAM NL (AMSTERDAM) coordinator 165˙598.00

Map

 Project objective

Insects are gaining resistance to commercially available pesticides and effective insecticides (e.g. neonicotinoids) are currently being banned. Consequently, there is a real threat that the EU vegetable production will be affected. Wild tomato species have the ability to defend themselves by producing natural defence compounds that have a toxic or repellent effect on insects. These compounds are produced and stored in glandular hairs (trichomes) on the plant stem and leaf surface. Extensive breeding in protected environments led to the loss of these defence compounds in cultivated tomatoes. It was previously shown that the introduction of the terpene 7-epizingiberene biosynthetic pathway from a wild tomato in trichomes of cultivated tomato results in an enhanced resistance to insects. However, the regulatory factors that govern the production of these defence compounds seem also essential for successful incorporation of ‘wild resistance’ into breeding material. Here, I aim to discover metabolic defence mechanisms present in the trichomes of wild tomato species that can be re-introduced into cultivated tomato with a focus on post-transcriptional regulation of biosynthetic pathways. I will evaluate insect resistance in a collection of wild and cultivated tomato accessions and associate phenotypic and transcriptional data via a Systems Biology approach. I will also sequence small RNAs and compare them quantitatively with messenger RNAs to identify post-transcriptional regulations. Next, I will follow a comparative genomic approach by mapping the selected transcripts to their corresponding tomato genomes to associate polymorphisms and resistance phenotypes. These results will be directly translated into molecular markers that the industry can implement in breeding programmes. This proposal will help me become an independent researcher, combining my background in plant biology with knowledge on bioinformatics, biostatistics and state-of-the-art technology.

 Publications

year authors and title journal last update
List of publications.
2016 Paula J. M. van Kleeff, Marc Galland, Robert C. Schuurink, Petra M. Bleeker
Small RNAs from Bemisia tabaci Are Transferred to Solanum lycopersicum Phloem during Feeding
published pages: , ISSN: 1664-462X, DOI: 10.3389/fpls.2016.01759
Frontiers in Plant Science 7 2019-07-23

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The information about "DURETO" are provided by the European Opendata Portal: CORDIS opendata.

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