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Rearm cultivated tomato with natural and durable resistance mechanisms from wild tomato species

Total Cost €


EC-Contrib. €






 DURETO project word cloud

Explore the words cloud of the DURETO project. It provides you a very rough idea of what is the project "DURETO" about.

insecticides    consequently    genomes    extensive    vegetable    compare    associate    discover    toxic    stored    species    gaining    collection    polymorphisms    genomic    rnas    data    mechanisms    insects    repellent    terpene    shown    glandular    tomato    neonicotinoids    hairs    industry    small    surface    corresponding    combining    regulatory    defend    phenotypic    material    insect    themselves    plant    protected    follow    me    cultivated    govern    epizingiberene    effect    re    biostatistics    tomatoes    led    stem    background    successful    transcripts    leaf    banned    markers    bioinformatics    natural    phenotypes    defence    introduction    regulations    transcriptional    post    previously    sequence    trichomes    metabolic    researcher    commercially    accessions    environments    producing    messenger    regulation    threat    compounds    independent    seem    wild    incorporation    molecular    translated    resistance    breeding    mapping    enhanced    quantitatively    biosynthetic    pesticides    biology   

Project "DURETO" data sheet

The following table provides information about the project.


Organization address
address: SPUI 21
postcode: 1012WX

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Project website
 Total cost 165˙598 €
 EC max contribution 165˙598 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-05-01   to  2017-04-30


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

Insects are gaining resistance to commercially available pesticides and effective insecticides (e.g. neonicotinoids) are currently being banned. Consequently, there is a real threat that the EU vegetable production will be affected. Wild tomato species have the ability to defend themselves by producing natural defence compounds that have a toxic or repellent effect on insects. These compounds are produced and stored in glandular hairs (trichomes) on the plant stem and leaf surface. Extensive breeding in protected environments led to the loss of these defence compounds in cultivated tomatoes. It was previously shown that the introduction of the terpene 7-epizingiberene biosynthetic pathway from a wild tomato in trichomes of cultivated tomato results in an enhanced resistance to insects. However, the regulatory factors that govern the production of these defence compounds seem also essential for successful incorporation of ‘wild resistance’ into breeding material. Here, I aim to discover metabolic defence mechanisms present in the trichomes of wild tomato species that can be re-introduced into cultivated tomato with a focus on post-transcriptional regulation of biosynthetic pathways. I will evaluate insect resistance in a collection of wild and cultivated tomato accessions and associate phenotypic and transcriptional data via a Systems Biology approach. I will also sequence small RNAs and compare them quantitatively with messenger RNAs to identify post-transcriptional regulations. Next, I will follow a comparative genomic approach by mapping the selected transcripts to their corresponding tomato genomes to associate polymorphisms and resistance phenotypes. These results will be directly translated into molecular markers that the industry can implement in breeding programmes. This proposal will help me become an independent researcher, combining my background in plant biology with knowledge on bioinformatics, biostatistics and state-of-the-art technology.


year authors and title journal last update
List of publications.
2016 Paula J. M. van Kleeff, Marc Galland, Robert C. Schuurink, Petra M. Bleeker
Small RNAs from Bemisia tabaci Are Transferred to Solanum lycopersicum Phloem during Feeding
published pages: , ISSN: 1664-462X, DOI: 10.3389/fpls.2016.01759
Frontiers in Plant Science 7 2019-07-23

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The information about "DURETO" are provided by the European Opendata Portal: CORDIS opendata.

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