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Micropod

MICROPOrous Devices for next-generation therapeutic delivery

Total Cost €

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EC-Contrib. €

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Partnership

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 Micropod project word cloud

Explore the words cloud of the Micropod project. It provides you a very rough idea of what is the project "Micropod" about.

small    biologics    invasive    precise    porous    micromanufacturing    infusion    translate    cearbhaill    advantages    designed    stick    synergise    passive    microneedle    host    patients    degradation    leader    microneedles    reintegrating    dublin    device    commercial    permeability    hypodermic    limiting    injuries    proximity    aid    medical    hollow    suffers    engineer    prohibitively    efficient    therapeutic    interconnected    penetration    michael    biomedical    performance    therapeutics    bed    innovation    proposes    expensive    microdevices    manufacture    expertise    soft    effect    consistent    implementing    vaccines    locations    eoin    bioengineering    university    dr    ireland    computational    platform    oral    returned    capillary    transdermal    career    skin    drug    molecules    risk    porosity    tissue    prone    dermal    limited    scaling    biotech    techniques    patches    minimally    molecule    manufacturing    needle    scalable    prof    mechanical    proficiency    poor    rapid    intestinal    phobia    close    absorption    classic    lecturer    college    gilchrist    fellowship   

Project "Micropod" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN 

Organization address
address: BELFIELD
city: DUBLIN
postcode: 4
website: www.ucd.ie

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Ireland [IE]
 Project website http://mdd.ucd.ie
 Total cost 187˙866 €
 EC max contribution 187˙866 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-RI
 Starting year 2015
 Duration (year-month-day) from 2015-04-14   to  2017-04-13

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN IE (DUBLIN) coordinator 187˙866.00

Map

 Project objective

Dr. Eoin O’Cearbhaill, a Biomedical Engineer, recently returned to Ireland to become a Lecturer in Bioengineering at University College Dublin. This fellowship will enable him to work with Prof. Michael Gilchrist to develop his career by implementing a research platform based on medical devices for therapeutic delivery, with a specific focus on microneedles. Microneedle transdermal patches are an important advance in the delivery of therapeutics, especially vaccines and biotech molecules. They offer advantages over the classic approaches of hypodermic drug delivery, (needle phobia, risk of needle stick injuries), oral delivery (degradation and poor intestinal permeability of biologics), and traditional skin patches (limited to passive delivery of small molecules). The traditional hollow needle design suffers from a scaling effect, limiting mechanical performance at the penetration depth required for efficient absorption and large molecule delivery. Current microneedle patches targeting transdermal delivery are often prohibitively expensive to manufacture and are prone to mechanical failure. Here, Dr. O’Cearbhaill proposes the development of microneedle patches with interconnected porosity, aimed at consistent, rapid delivery to dermal tissue, in close proximity to the capillary bed. This platform technology can also be applied to other minimally invasive devices designed to provide controlled therapeutic infusion to precise locations. The applicant will develop porous microdevices, using manufacturing techniques that are scalable and cost-effective, enhancing the commercial value and potential to rapidly translate this technology to patients. The reintegrating applicant’s proficiency in medical device concept development will synergise with the host’s expertise in computational modelling of penetration in soft tissue and micromanufacturing to aid in the applicant’s development as a leader in medical device design and innovation.

 Publications

year authors and title journal last update
List of publications.
2015 Cahill, Ellen Mary; O\'Cearbhaill, Eoin D.
Towards Biofunctional Microneedles for Stimulus Responsive Drug Delivery
published pages: , ISSN: 1520-4812, DOI: 10.1021/acs.bioconjchem.5b00211
Bioconjugate Chemistry 2019-06-14

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The information about "MICROPOD" are provided by the European Opendata Portal: CORDIS opendata.

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