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Periodontal Regeneration through Femtosecond laser Action

Total Cost €


EC-Contrib. €






 PRe-FActo project word cloud

Explore the words cloud of the PRe-FActo project. It provides you a very rough idea of what is the project "PRe-FActo" about.

femtosecond    materials    supplemented    aluminum    disease    toxicology    leeds    attachment    skills    qualified    revival    duggal    lasers    regenerative    fibroblasts    mixed    pursuing    calcium    fellowship    public    supervision    tested    jha    biomaterial    rtas    host    prevention    engineering    deal    bonded    monty    collagen    dynamic    material    clinical    training    culture    rounded    fellow    synthesis    doped    tests    fluoride    cell    surface    gel    exploring    university    erbium    beneficial    listed    supervisor    scientific    prof    intervened    characterization    disciplinary    tooth    topology    potentially    bioengineer    chitosan    facto    sintering    phosphates    drug    ultrafast    pulsed    successful    densified    am    periodontitis    oxides    risks    irradiation    laser    therapy    investigation    effect    uol    antibacterial    cross    health    say    global    sintered    ions    academic    career    cerium    area    histological    outcome    animesh    researcher    periodontium    photo    aj   

Project "PRe-FActo" data sheet

The following table provides information about the project.


Organization address
city: LEEDS
postcode: LS2 9JT

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-01-01   to  2017-12-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY OF LEEDS UK (LEEDS) coordinator 183˙454.00


 Project objective

The PRE-Facto fellowship aims to develop a new regenerative approach which potentially will promote the revival of the periodontium, while a successful outcome may lead also to the prevention of the disease when intervened early. Within my research I am going to develop a new biomaterial (calcium phosphates doped with ions of say, cerium and erbium oxides, fluoride and aluminum (3) ions) with antibacterial properties which will be densified and bonded on the tooth surface after the irradiation with an ultrafast pulsed laser (femtosecond laser). In order to promote the attachment of the fibroblasts, the biomaterial will be mixed with collagen gel (or chitosan) while the effect of the surface topology will be also tested. For my research training as a bioengineer within which I aim to solve periodontitis as a global problem I will deal with the following Research Training Activities (RTAs); i) Synthesis, characterization and delivery of the biomaterial; ii) Sintering of the materials with femtosecond laser - characterization of the sintered area; iii) Cell culture and histological studies for exploring the regenerative potential of the material; iv) Toxicology tests and potential risks investigation. This training is not only beneficial for the fellow’s scientific career development, but also for the host institute (the University of Leeds) and the general public health. The above listed training activities will be supplemented by a number of non-Technical skills for my career development. As a result of this cross-disciplinary project the fellow will be a well-rounded bioengineer researcher who in future will be become qualified for pursuing an academic career at the University of Leeds in the area of advanced drug delivery and photo-dynamic therapy using novel femtosecond lasers. Necessary research training and supervision at the UoL will be provided by the Engineering supervisor Prof. Animesh Jha (AJ) and the clinical supervisor Prof . Monty Duggal.


year authors and title journal last update
List of publications.
2018 A.D. Anastasiou, S. Strafford, C.L. Thomson, J. Gardy, T.J. Edwards, M. Malinowski, S.A. Hussain, N.K. Metzger, A. Hassanpour, C.T.A. Brown, A.P. Brown, M.S. Duggal, A. Jha
Exogenous mineralization of hard tissues using photo-absorptive minerals and femto-second lasers; the case of dental enamel
published pages: , ISSN: 1742-7061, DOI: 10.1016/j.actbio.2018.02.012
Acta Biomaterialia 2019-06-18

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The information about "PRE-FACTO" are provided by the European Opendata Portal: CORDIS opendata.

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