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Periodontal Regeneration through Femtosecond laser Action

Total Cost €


EC-Contrib. €






 PRe-FActo project word cloud

Explore the words cloud of the PRe-FActo project. It provides you a very rough idea of what is the project "PRe-FActo" about.

skills    health    intervened    fellowship    culture    global    outcome    bioengineer    aj    academic    fibroblasts    say    public    uol    mixed    beneficial    antibacterial    photo    leeds    lasers    gel    surface    characterization    duggal    revival    doped    supervisor    attachment    densified    fluoride    materials    career    monty    ions    investigation    successful    ultrafast    rounded    femtosecond    tested    oxides    potentially    scientific    effect    dynamic    collagen    bonded    pursuing    histological    synthesis    supervision    toxicology    training    material    disease    jha    rtas    university    facto    qualified    sintered    researcher    laser    area    periodontitis    sintering    am    tooth    periodontium    clinical    erbium    therapy    regenerative    cross    chitosan    risks    phosphates    biomaterial    disciplinary    supplemented    cerium    animesh    prevention    prof    irradiation    host    exploring    engineering    listed    calcium    cell    topology    pulsed    fellow    deal    aluminum    drug    tests   

Project "PRe-FActo" data sheet

The following table provides information about the project.


Organization address
city: LEEDS
postcode: LS2 9JT

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-01-01   to  2017-12-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY OF LEEDS UK (LEEDS) coordinator 183˙454.00


 Project objective

The PRE-Facto fellowship aims to develop a new regenerative approach which potentially will promote the revival of the periodontium, while a successful outcome may lead also to the prevention of the disease when intervened early. Within my research I am going to develop a new biomaterial (calcium phosphates doped with ions of say, cerium and erbium oxides, fluoride and aluminum (3) ions) with antibacterial properties which will be densified and bonded on the tooth surface after the irradiation with an ultrafast pulsed laser (femtosecond laser). In order to promote the attachment of the fibroblasts, the biomaterial will be mixed with collagen gel (or chitosan) while the effect of the surface topology will be also tested. For my research training as a bioengineer within which I aim to solve periodontitis as a global problem I will deal with the following Research Training Activities (RTAs); i) Synthesis, characterization and delivery of the biomaterial; ii) Sintering of the materials with femtosecond laser - characterization of the sintered area; iii) Cell culture and histological studies for exploring the regenerative potential of the material; iv) Toxicology tests and potential risks investigation. This training is not only beneficial for the fellow’s scientific career development, but also for the host institute (the University of Leeds) and the general public health. The above listed training activities will be supplemented by a number of non-Technical skills for my career development. As a result of this cross-disciplinary project the fellow will be a well-rounded bioengineer researcher who in future will be become qualified for pursuing an academic career at the University of Leeds in the area of advanced drug delivery and photo-dynamic therapy using novel femtosecond lasers. Necessary research training and supervision at the UoL will be provided by the Engineering supervisor Prof. Animesh Jha (AJ) and the clinical supervisor Prof . Monty Duggal.


year authors and title journal last update
List of publications.
2018 A.D. Anastasiou, S. Strafford, C.L. Thomson, J. Gardy, T.J. Edwards, M. Malinowski, S.A. Hussain, N.K. Metzger, A. Hassanpour, C.T.A. Brown, A.P. Brown, M.S. Duggal, A. Jha
Exogenous mineralization of hard tissues using photo-absorptive minerals and femto-second lasers; the case of dental enamel
published pages: , ISSN: 1742-7061, DOI: 10.1016/j.actbio.2018.02.012
Acta Biomaterialia 2019-06-18

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The information about "PRE-FACTO" are provided by the European Opendata Portal: CORDIS opendata.

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