Opendata, web and dolomites

HITCHIPDIAG

Rapid and Inexpensive Diagnosis of Heparin Induced Thrombocytopenia Using Glycan Arrays Containing Synthetic Glycosaminoglycans

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 HITCHIPDIAG project word cloud

Explore the words cloud of the HITCHIPDIAG project. It provides you a very rough idea of what is the project "HITCHIPDIAG" about.

ip    million    glycosaminoglycans    grant    annually    glycosaminoglycan    complications    suffer    hipa    thrombosis    hit    dangerous    discovered    surgery    anticoagulant    incorporate    cardiopulmonary    dialysis    investors    mortality    minutes    antibodies    glycan    plan    develops    oligosaccharides    company    screen    platelet    detected    microarray    coronary    patients    diagnostic    reliabilities    model    diagnostics    surfaces    diagnose    gag    markers    detect    adverse    microarrays    structure    automated    wellbeing    thrombocytopenia    accuracy    patient    synthetic    bypass    diagnosis    protocols    inexpensive    syndrome    carbohydrate    reduce    organ    effect    instrument    tests    deep    rapid    arrays    standard    business    customers    assembly    specificity    markets    printing    cheaper    heparin    space    blood    acute    administration    faster    onto    commercialize    basis    containing    vein    autoheparin    strategy    20    yielded    prepare    maipa    commercial    twelve    erc    infarction   

Project "HITCHIPDIAG" data sheet

The following table provides information about the project.

Coordinator
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV 

Organization address
address: HOFGARTENSTRASSE 8
city: MUENCHEN
postcode: 80539
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 147˙094 €
 EC max contribution 147˙094 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2014-PoC
 Funding Scheme ERC-POC
 Starting year 2015
 Duration (year-month-day) from 2015-04-01   to  2016-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV DE (MUENCHEN) coordinator 147˙094.00

Map

 Project objective

Rapid and Inexpensive Diagnosis of Heparin Induced Thrombocytopenia Using Glycan Arrays Containing Synthetic Glycosaminoglycans Heparin, a complex glycosaminoglycan (GAG) carbohydrate, is the most commonly used anticoagulant. Twelve million patients in the EU are treated annually for conditions including acute coronary syndrome, deep-vein thrombosis and cardiopulmonary bypass surgery. Heparin-induced thrombocytopenia (HIT) is a dangerous adverse side effect of heparin administration. HIT-II develops after major surgery or dialysis and results in infarction, multi-organ failure and 20% mortality. In Europe 100,000 patients develop HIT-II annually. Currently, two HIT-II diagnostics are available. The HIPA and MAIPA tests detect antibodies against a complex of heparin and platelet factor 4 but suffer from low diagnostic specificity and accuracy. Faster, more reliable and cheaper methods to diagnose complications after administration of heparin are needed to improve patient wellbeing and reduce costs. The ERC Advanced grant AUTOHEPARIN yielded an instrument for the automated assembly of defined oligosaccharides. GAG glycan microarrays were produced by printing GAG oligosaccharides onto surfaces and used to screen patient blood. Specific glycan markers of high diagnostic value were discovered to detected HIT-II within minutes and reliabilities well above existing tests. The overall goal of the project is to establish the business model for a company that will focus on the production of GAG glycan arrays as HIT diagnostic. Specific activities include: 1) Development of standard protocols to detect HIT-II using GAG glycan microarray; 2) Plan and cost structure for GAG arrays production; 3) Analysis of the IP space and development of an IP strategy; 4) Evaluate potential markets and establish basis for commercial discussion with potential customers; 5) Prepare business plan for discussions with investors; 6) Incorporate company to commercialize GAG arrays as HIT diagnostic

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "HITCHIPDIAG" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "HITCHIPDIAG" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

EVOMENS (2020)

The evolution of menstruation in primates

Read More  

GWAS2FUNC (2019)

From GWAS to functional studies: Tackling the complex nature of brain disorders

Read More  

NEUROPRECISE (2019)

Precision medicine in traumatic brain injury using individual neurosteroid response

Read More