BHIVE SIGNED
Bio-derived HIgh Value polymers through novel Enzyme function
Total Cost €
0EC-Contrib. €
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Explore the words cloud of the BHIVE project. It provides you a very rough idea of what is the project "BHIVE" about.
Project "BHIVE" data sheet
The following table provides information about the project.
| Coordinator |
AALTO KORKEAKOULUSAATIO SR
Organization address contact info |
| Coordinator Country | Finland [FI] |
| Total cost | 1˙977˙781 € |
| EC max contribution | 1˙977˙781 € (100%) |
| Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
| Code Call | ERC-2014-CoG |
| Funding Scheme | ERC-COG |
| Starting year | 2015 |
| Duration (year-month-day) | from 2015-09-01 to 2020-08-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | AALTO KORKEAKOULUSAATIO SR | FI (ESPOO) | coordinator | 1˙977˙781.00 |
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Project objective
Recent advances in systems-level study of cells and organisms have revealed the enormous potential to live more sustainably through better use of biological processes. Plants sustainably synthesize the most abundant and diverse materials on Earth. By applying recent advances in life science technology, we can better harness renewable plant resources and bioconversion processes, to develop environmentally and politically sustainable human enterprise and lifestyles. At the same time, the global market for high-value biochemicals and bioplastics from forest and agricultural sources is rapidly increasing, which presents new opportunities for forest and agricultural sectors.
The overall aim of BHIVE is to illuminate uncharted regions of genome and metagenome sequences to discover entirely new protein families that can be used to sustainably synthesize novel, high-value biomaterials from renewable plant resources. The approach will include three parallel research thrusts: 1) strategic analysis of transcriptome and metagenome sequences to identify proteins with entirely unknown function relevant to biomass (lignocellulose) transformation, 2) mapping of uncharted regions within phylogenetic trees of poorly characterized enzyme families with recognized potential to modify the chemistry and biophysical properties of plant polysaccharides, and 3) the design and development of novel enzyme screens to directly address the increasing limitations of existing assays to uncover entirely new protein functions. BHIVE will be unique in its undivided focus on characterizing lignocellulose-active proteins encoded by the 30-40% of un-annotated sequence, or genomic “dark matter”, typical of nearly all genome sequences. In this way, BHIVE tackles a key constraint to fully realizing the societal and environmental benefits of the genomics era.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2019 |
Ville Aumala, Filip Mollerup, Edita Jurak, Fabian Blume, Johanna Karppi, Antti E. Koistinen, Eva Schuiten, Moritz Voß, Uwe Bornscheuer, Jan Deska, Emma R. Master Biocatalytic Production of Amino Carbohydrates through Oxidoreductase and Transaminase Cascades published pages: 848-857, ISSN: 1864-5631, DOI: 10.1002/cssc.201802580 |
ChemSusChem 12/4 | 2020-03-05 |
| 2017 |
Galina Mai-Gisondi, Hannu Maaheimo, Sun-Li Chong, Sandra Hinz, Maija Tenkanen, Emma Master Functional comparison of versatile carbohydrate esterases from families CE1, CE6 and CE16 on acetyl-4- O -methylglucuronoxylan and acetyl-galactoglucomannan published pages: 2398-2405, ISSN: 0304-4165, DOI: 10.1016/j.bbagen.2017.06.002 |
Biochimica et Biophysica Acta (BBA) - General Subjects 1861/9 | 2020-03-05 |
| 2016 |
Filip Mollerup, Emma Master Influence of a family 29 carbohydrate binding module on the recombinant production of galactose oxidase in Pichia pastoris published pages: 176-183, ISSN: 2352-3409, DOI: 10.1016/j.dib.2015.11.032 |
Data in Brief 6 | 2019-09-27 |
| 2018 |
Fakhria M. Razeq, Edita Jurak, Peter J. Stogios, Ruoyu Yan, Maija Tenkanen, Mirjam A. Kabel, Weijun Wang, Emma R. Master A novel acetyl xylan esterase enabling complete deacetylation of substituted xylans published pages: , ISSN: 1754-6834, DOI: 10.1186/s13068-018-1074-3 |
Biotechnology for Biofuels 11/1 | 2019-09-27 |
| 2017 |
Mabel T. Wong, Weijun Wang, Marie Couturier, Fakhria M. Razeq, Vincent Lombard, Pascal Lapebie, Elizabeth A. Edwards, Nicolas Terrapon, Bernard Henrissat, Emma R. Master Comparative Metagenomics of Cellulose- and Poplar Hydrolysate-Degrading Microcosms from Gut Microflora of the Canadian Beaver (Castor canadensis) and North American Moose (Alces americanus) after Long-Term Enrichment published pages: , ISSN: 1664-302X, DOI: 10.3389/fmicb.2017.02504 |
Frontiers in Microbiology 8 | 2019-09-27 |
| 2018 |
Weijun Wang, Nikola Andric, Cody Sarch, Bruno T. Silva, Maija Tenkanen, Emma R. Master Constructing arabinofuranosidases for dual arabinoxylan debranching activity published pages: 41-49, ISSN: 0006-3592, DOI: 10.1002/bit.26445 |
Biotechnology and Bioengineering 115/1 | 2019-09-27 |
| 2017 |
Robyn E. Goacher, Erick J. Braham, Courtney L. Michienzi, Robert M. Flick, Alexander F. Yakunin, Emma R. Master Direct analysis by Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) reveals action of bacterial laccase-mediator system on both hardwood and softwood samples published pages: , ISSN: 0031-9317, DOI: 10.1111/ppl.12688 |
Physiologia Plantarum | 2019-09-27 |
| 2018 |
Benjamin MacCormick, Thu V. Vuong, Emma R. Master Chemo-enzymatic Synthesis of Clickable Xylo-oligosaccharide Monomers from Hardwood 4- O -Methylglucuronoxylan published pages: 521-530, ISSN: 1525-7797, DOI: 10.1021/acs.biomac.7b01642 |
Biomacromolecules 19/2 | 2019-09-27 |
| 2017 |
Thu V. Vuong, Bing Liu, Mats Sandgren, Emma R. Master Microplate-Based Detection of Lytic Polysaccharide Monooxygenase Activity by Fluorescence-Labeling of Insoluble Oxidized Products published pages: 610-616, ISSN: 1525-7797, DOI: 10.1021/acs.biomac.6b01790 |
Biomacromolecules 18/2 | 2019-09-27 |
| 2017 |
Kuisma Littunen, Galina Mai-Gisondi, Jukka Seppälä, Emma R. Master Enzymatically Debranched Xylans in Graft Copolymerization published pages: , ISSN: 1525-7797, DOI: 10.1021/acs.biomac.7b00229 |
Biomacromolecules | 2019-09-27 |
| 2017 |
Galina Mai-Gisondi, Emma R. Master Colorimetric Detection of Acetyl Xylan Esterase Activities published pages: 45-57, ISSN: , DOI: 10.1007/978-1-4939-6899-2_5 |
Methods in Molecular Biology | 2019-09-27 |
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