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Bio-derived HIgh Value polymers through novel Enzyme function

Total Cost €


EC-Contrib. €






 BHIVE project word cloud

Explore the words cloud of the BHIVE project. It provides you a very rough idea of what is the project "BHIVE" about.

live    genome    era    biochemicals    un    discover    enzyme    modify    diverse    mapping    regions    thrusts    global    bhive    entirely    forest    characterizing    illuminate    transcriptome    lignocellulose    realizing    metagenome    plants    unknown    harness    uncover    chemistry    parallel    genomics    renewable    genomic    transformation    tackles    environmentally    dark    materials    protein    function    enterprise    nearly    functions    poorly    cells    lifestyles    recent    human    market    societal    biological    time    sustainably    environmental    annotated    bioconversion    politically    life    bioplastics    synthesize    sustainable    biomaterials    science    abundant    constraint    uncharted    trees    strategic    sectors    polysaccharides    encoded    enormous    agricultural    limitations    families    sources    screens    earth    organisms    sequences    revealed    benefits    plant    assays    biomass    phylogenetic    undivided    active    sequence    proteins    biophysical    40   

Project "BHIVE" data sheet

The following table provides information about the project.


Organization address
address: OTAKAARI 1
city: ESPOO
postcode: 2150

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Finland [FI]
 Total cost 1˙977˙781 €
 EC max contribution 1˙977˙781 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2014-CoG
 Funding Scheme ERC-COG
 Starting year 2015
 Duration (year-month-day) from 2015-09-01   to  2020-08-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    AALTO KORKEAKOULUSAATIO SR FI (ESPOO) coordinator 1˙977˙781.00


 Project objective

Recent advances in systems-level study of cells and organisms have revealed the enormous potential to live more sustainably through better use of biological processes. Plants sustainably synthesize the most abundant and diverse materials on Earth. By applying recent advances in life science technology, we can better harness renewable plant resources and bioconversion processes, to develop environmentally and politically sustainable human enterprise and lifestyles. At the same time, the global market for high-value biochemicals and bioplastics from forest and agricultural sources is rapidly increasing, which presents new opportunities for forest and agricultural sectors.

The overall aim of BHIVE is to illuminate uncharted regions of genome and metagenome sequences to discover entirely new protein families that can be used to sustainably synthesize novel, high-value biomaterials from renewable plant resources. The approach will include three parallel research thrusts: 1) strategic analysis of transcriptome and metagenome sequences to identify proteins with entirely unknown function relevant to biomass (lignocellulose) transformation, 2) mapping of uncharted regions within phylogenetic trees of poorly characterized enzyme families with recognized potential to modify the chemistry and biophysical properties of plant polysaccharides, and 3) the design and development of novel enzyme screens to directly address the increasing limitations of existing assays to uncover entirely new protein functions. BHIVE will be unique in its undivided focus on characterizing lignocellulose-active proteins encoded by the 30-40% of un-annotated sequence, or genomic “dark matter”, typical of nearly all genome sequences. In this way, BHIVE tackles a key constraint to fully realizing the societal and environmental benefits of the genomics era.


year authors and title journal last update
List of publications.
2019 Ville Aumala, Filip Mollerup, Edita Jurak, Fabian Blume, Johanna Karppi, Antti E. Koistinen, Eva Schuiten, Moritz Voß, Uwe Bornscheuer, Jan Deska, Emma R. Master
Biocatalytic Production of Amino Carbohydrates through Oxidoreductase and Transaminase Cascades
published pages: 848-857, ISSN: 1864-5631, DOI: 10.1002/cssc.201802580
ChemSusChem 12/4 2020-03-05
2017 Galina Mai-Gisondi, Hannu Maaheimo, Sun-Li Chong, Sandra Hinz, Maija Tenkanen, Emma Master
Functional comparison of versatile carbohydrate esterases from families CE1, CE6 and CE16 on acetyl-4- O -methylglucuronoxylan and acetyl-galactoglucomannan
published pages: 2398-2405, ISSN: 0304-4165, DOI: 10.1016/j.bbagen.2017.06.002
Biochimica et Biophysica Acta (BBA) - General Subjects 1861/9 2020-03-05
2016 Filip Mollerup, Emma Master
Influence of a family 29 carbohydrate binding module on the recombinant production of galactose oxidase in Pichia pastoris
published pages: 176-183, ISSN: 2352-3409, DOI: 10.1016/j.dib.2015.11.032
Data in Brief 6 2019-09-27
2018 Fakhria M. Razeq, Edita Jurak, Peter J. Stogios, Ruoyu Yan, Maija Tenkanen, Mirjam A. Kabel, Weijun Wang, Emma R. Master
A novel acetyl xylan esterase enabling complete deacetylation of substituted xylans
published pages: , ISSN: 1754-6834, DOI: 10.1186/s13068-018-1074-3
Biotechnology for Biofuels 11/1 2019-09-27
2017 Mabel T. Wong, Weijun Wang, Marie Couturier, Fakhria M. Razeq, Vincent Lombard, Pascal Lapebie, Elizabeth A. Edwards, Nicolas Terrapon, Bernard Henrissat, Emma R. Master
Comparative Metagenomics of Cellulose- and Poplar Hydrolysate-Degrading Microcosms from Gut Microflora of the Canadian Beaver (Castor canadensis) and North American Moose (Alces americanus) after Long-Term Enrichment
published pages: , ISSN: 1664-302X, DOI: 10.3389/fmicb.2017.02504
Frontiers in Microbiology 8 2019-09-27
2018 Weijun Wang, Nikola Andric, Cody Sarch, Bruno T. Silva, Maija Tenkanen, Emma R. Master
Constructing arabinofuranosidases for dual arabinoxylan debranching activity
published pages: 41-49, ISSN: 0006-3592, DOI: 10.1002/bit.26445
Biotechnology and Bioengineering 115/1 2019-09-27
2017 Robyn E. Goacher, Erick J. Braham, Courtney L. Michienzi, Robert M. Flick, Alexander F. Yakunin, Emma R. Master
Direct analysis by Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) reveals action of bacterial laccase-mediator system on both hardwood and softwood samples
published pages: , ISSN: 0031-9317, DOI: 10.1111/ppl.12688
Physiologia Plantarum 2019-09-27
2018 Benjamin MacCormick, Thu V. Vuong, Emma R. Master
Chemo-enzymatic Synthesis of Clickable Xylo-oligosaccharide Monomers from Hardwood 4- O -Methylglucuronoxylan
published pages: 521-530, ISSN: 1525-7797, DOI: 10.1021/acs.biomac.7b01642
Biomacromolecules 19/2 2019-09-27
2017 Thu V. Vuong, Bing Liu, Mats Sandgren, Emma R. Master
Microplate-Based Detection of Lytic Polysaccharide Monooxygenase Activity by Fluorescence-Labeling of Insoluble Oxidized Products
published pages: 610-616, ISSN: 1525-7797, DOI: 10.1021/acs.biomac.6b01790
Biomacromolecules 18/2 2019-09-27
2017 Kuisma Littunen, Galina Mai-Gisondi, Jukka Seppälä, Emma R. Master
Enzymatically Debranched Xylans in Graft Copolymerization
published pages: , ISSN: 1525-7797, DOI: 10.1021/acs.biomac.7b00229
Biomacromolecules 2019-09-27
2017 Galina Mai-Gisondi, Emma R. Master
Colorimetric Detection of Acetyl Xylan Esterase Activities
published pages: 45-57, ISSN: , DOI: 10.1007/978-1-4939-6899-2_5
Methods in Molecular Biology 2019-09-27

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