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Bio-derived HIgh Value polymers through novel Enzyme function

Total Cost €


EC-Contrib. €






 BHIVE project word cloud

Explore the words cloud of the BHIVE project. It provides you a very rough idea of what is the project "BHIVE" about.

biochemicals    sequences    sustainable    politically    bioconversion    lignocellulose    transcriptome    lifestyles    characterizing    chemistry    phylogenetic    limitations    undivided    function    life    parallel    recent    revealed    entirely    proteins    realizing    plants    poorly    functions    live    renewable    science    biomaterials    un    environmental    biological    genome    diverse    families    cells    dark    organisms    biophysical    era    tackles    annotated    active    market    bhive    materials    enormous    assays    sectors    screens    transformation    uncharted    time    forest    bioplastics    synthesize    protein    sequence    genomic    illuminate    thrusts    biomass    agricultural    40    uncover    sustainably    mapping    modify    sources    benefits    polysaccharides    enzyme    plant    encoded    unknown    regions    earth    strategic    discover    nearly    environmentally    constraint    enterprise    human    trees    abundant    genomics    global    societal    metagenome    harness   

Project "BHIVE" data sheet

The following table provides information about the project.


Organization address
address: OTAKAARI 1
city: ESPOO
postcode: 2150

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Finland [FI]
 Total cost 1˙977˙781 €
 EC max contribution 1˙977˙781 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2014-CoG
 Funding Scheme ERC-COG
 Starting year 2015
 Duration (year-month-day) from 2015-09-01   to  2020-08-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    AALTO KORKEAKOULUSAATIO SR FI (ESPOO) coordinator 1˙977˙781.00


 Project objective

Recent advances in systems-level study of cells and organisms have revealed the enormous potential to live more sustainably through better use of biological processes. Plants sustainably synthesize the most abundant and diverse materials on Earth. By applying recent advances in life science technology, we can better harness renewable plant resources and bioconversion processes, to develop environmentally and politically sustainable human enterprise and lifestyles. At the same time, the global market for high-value biochemicals and bioplastics from forest and agricultural sources is rapidly increasing, which presents new opportunities for forest and agricultural sectors.

The overall aim of BHIVE is to illuminate uncharted regions of genome and metagenome sequences to discover entirely new protein families that can be used to sustainably synthesize novel, high-value biomaterials from renewable plant resources. The approach will include three parallel research thrusts: 1) strategic analysis of transcriptome and metagenome sequences to identify proteins with entirely unknown function relevant to biomass (lignocellulose) transformation, 2) mapping of uncharted regions within phylogenetic trees of poorly characterized enzyme families with recognized potential to modify the chemistry and biophysical properties of plant polysaccharides, and 3) the design and development of novel enzyme screens to directly address the increasing limitations of existing assays to uncover entirely new protein functions. BHIVE will be unique in its undivided focus on characterizing lignocellulose-active proteins encoded by the 30-40% of un-annotated sequence, or genomic “dark matter”, typical of nearly all genome sequences. In this way, BHIVE tackles a key constraint to fully realizing the societal and environmental benefits of the genomics era.


year authors and title journal last update
List of publications.
2019 Ville Aumala, Filip Mollerup, Edita Jurak, Fabian Blume, Johanna Karppi, Antti E. Koistinen, Eva Schuiten, Moritz Voß, Uwe Bornscheuer, Jan Deska, Emma R. Master
Biocatalytic Production of Amino Carbohydrates through Oxidoreductase and Transaminase Cascades
published pages: 848-857, ISSN: 1864-5631, DOI: 10.1002/cssc.201802580
ChemSusChem 12/4 2020-03-05
2017 Galina Mai-Gisondi, Hannu Maaheimo, Sun-Li Chong, Sandra Hinz, Maija Tenkanen, Emma Master
Functional comparison of versatile carbohydrate esterases from families CE1, CE6 and CE16 on acetyl-4- O -methylglucuronoxylan and acetyl-galactoglucomannan
published pages: 2398-2405, ISSN: 0304-4165, DOI: 10.1016/j.bbagen.2017.06.002
Biochimica et Biophysica Acta (BBA) - General Subjects 1861/9 2020-03-05
2016 Filip Mollerup, Emma Master
Influence of a family 29 carbohydrate binding module on the recombinant production of galactose oxidase in Pichia pastoris
published pages: 176-183, ISSN: 2352-3409, DOI: 10.1016/j.dib.2015.11.032
Data in Brief 6 2019-09-27
2018 Fakhria M. Razeq, Edita Jurak, Peter J. Stogios, Ruoyu Yan, Maija Tenkanen, Mirjam A. Kabel, Weijun Wang, Emma R. Master
A novel acetyl xylan esterase enabling complete deacetylation of substituted xylans
published pages: , ISSN: 1754-6834, DOI: 10.1186/s13068-018-1074-3
Biotechnology for Biofuels 11/1 2019-09-27
2017 Mabel T. Wong, Weijun Wang, Marie Couturier, Fakhria M. Razeq, Vincent Lombard, Pascal Lapebie, Elizabeth A. Edwards, Nicolas Terrapon, Bernard Henrissat, Emma R. Master
Comparative Metagenomics of Cellulose- and Poplar Hydrolysate-Degrading Microcosms from Gut Microflora of the Canadian Beaver (Castor canadensis) and North American Moose (Alces americanus) after Long-Term Enrichment
published pages: , ISSN: 1664-302X, DOI: 10.3389/fmicb.2017.02504
Frontiers in Microbiology 8 2019-09-27
2018 Weijun Wang, Nikola Andric, Cody Sarch, Bruno T. Silva, Maija Tenkanen, Emma R. Master
Constructing arabinofuranosidases for dual arabinoxylan debranching activity
published pages: 41-49, ISSN: 0006-3592, DOI: 10.1002/bit.26445
Biotechnology and Bioengineering 115/1 2019-09-27
2017 Robyn E. Goacher, Erick J. Braham, Courtney L. Michienzi, Robert M. Flick, Alexander F. Yakunin, Emma R. Master
Direct analysis by Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) reveals action of bacterial laccase-mediator system on both hardwood and softwood samples
published pages: , ISSN: 0031-9317, DOI: 10.1111/ppl.12688
Physiologia Plantarum 2019-09-27
2018 Benjamin MacCormick, Thu V. Vuong, Emma R. Master
Chemo-enzymatic Synthesis of Clickable Xylo-oligosaccharide Monomers from Hardwood 4- O -Methylglucuronoxylan
published pages: 521-530, ISSN: 1525-7797, DOI: 10.1021/acs.biomac.7b01642
Biomacromolecules 19/2 2019-09-27
2017 Thu V. Vuong, Bing Liu, Mats Sandgren, Emma R. Master
Microplate-Based Detection of Lytic Polysaccharide Monooxygenase Activity by Fluorescence-Labeling of Insoluble Oxidized Products
published pages: 610-616, ISSN: 1525-7797, DOI: 10.1021/acs.biomac.6b01790
Biomacromolecules 18/2 2019-09-27
2017 Kuisma Littunen, Galina Mai-Gisondi, Jukka Seppälä, Emma R. Master
Enzymatically Debranched Xylans in Graft Copolymerization
published pages: , ISSN: 1525-7797, DOI: 10.1021/acs.biomac.7b00229
Biomacromolecules 2019-09-27
2017 Galina Mai-Gisondi, Emma R. Master
Colorimetric Detection of Acetyl Xylan Esterase Activities
published pages: 45-57, ISSN: , DOI: 10.1007/978-1-4939-6899-2_5
Methods in Molecular Biology 2019-09-27

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