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SHARS

Small HeteroAromatic Ring Synthesis: A Unified Approach

Total Cost €

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EC-Contrib. €

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Partnership

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Project "SHARS" data sheet

The following table provides information about the project.

Coordinator
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD 

Organization address
address: WELLINGTON SQUARE UNIVERSITY OFFICES
city: OXFORD
postcode: OX1 2JD
website: www.ox.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website http://anderson.chem.ox.ac.uk/lay.html
 Total cost 195˙454 €
 EC max contribution 195˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-08-01   to  2017-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD UK (OXFORD) coordinator 195˙454.00

Map

 Project objective

Five-membered ring heteroaromatics such as pyrroles, furans, thiophenes and isoxazoles form a cornerstone of medicinal and agrochemical research. Despite this importance, the predominant methods used by both academic and industrial researchers to access these frameworks still rely on chemistry developed up to a century ago, which suffers from several drawbacks. Chief amongst these is the restriction on substituent pattern that is intrinsic to these classical routes, which prevents decoration of the ring with a full range of contemporary functionality. This project seeks to address these shortcomings by developing a unified catalytic approach to these heterocycles through a fundamentally new ring synthesis mechanism. This chemistry can access, with ease, previously unattained substitution patterns, and permits the positioning of substituents at any or all of the 2-, 3- and 5-positions around the ring. Equal to the value of this reactivity and its products is the facility with which the key reaction substrates are prepared – in 2-5 steps from cheap, commercial alkyne and carbonyl building blocks. Alongside method development, an industrial engagement platform is planned which will allow the Experienced Researcher to interface directly with industrial partners in Europe via a secondment programme.

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The information about "SHARS" are provided by the European Opendata Portal: CORDIS opendata.

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