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TASPPI SIGNED

Targeted small-molecule Stabilisation of Protein-Protein Interactions

Total Cost €

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EC-Contrib. €

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Partnership

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Project "TASPPI" data sheet

The following table provides information about the project.

Coordinator
TECHNISCHE UNIVERSITEIT EINDHOVEN 

Organization address
address: GROENE LOPER 3
city: EINDHOVEN
postcode: 5612 AE
website: www.tue.nl/en

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Project website http://www.tasppi.eu/
 Total cost 3˙342˙323 €
 EC max contribution 3˙342˙323 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2015
 Funding Scheme MSCA-ITN-ETN
 Starting year 2016
 Duration (year-month-day) from 2016-02-01   to  2020-01-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TECHNISCHE UNIVERSITEIT EINDHOVEN NL (EINDHOVEN) coordinator 766˙122.00
2    ASTRAZENECA AB SE (SODERTAELJE) participant 527˙318.00
3    UNIVERSITY OF DUNDEE UK (DUNDEE) participant 273˙287.00
4    UNIVERSITY OF LEEDS UK (LEEDS) participant 273˙287.00
5    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) participant 262˙875.00
6    UNIVERSITA DEGLI STUDI DI SIENA IT (SIENA) participant 258˙061.00
7    CELLTECH R&D LIMITED UK (SLOUGH) participant 250˙513.00
8    LEAD DISCOVERY CENTER GMBH DE (DORTMUND) participant 249˙216.00
9    TAROS CHEMICALS GMBH & CO KG DE (Dortmund) participant 249˙216.00
10    UNIVERZITA KARLOVA CZ (PRAHA 1) participant 232˙422.00
11    UCB BIOPHARMA SRL BE (BRUXELLES) participant 0.00
12    GLAXOSMITHKLINE RESEARCH AND DEVELOPMENT LTD. UK (BRENTFORD) partner 0.00

Map

 Project objective

The goal of the TASPPI European Training Network (ETN) is the establishment of a highly interdisciplinary research and educational training platform for early stage scientists in the Chemical Life Sciences to overcome the inherent boundaries between academia and industry and to increase their employability in both areas. To this end we have teamed up in a consortium comprising 5 partners from industry (AstraZeneca, GlaxoSmithKline, UCB, Lead Disocvery Center, Taros Chemicals) and 6 partners from academia (Universities of Dundee, Eindhoven, Leeds, Lille, Prague, and Siena). The scientific objective of the multi-sectorial Training Network is the development and implementation of a multidisciplinary technology platform bringing together structural molecular biology, chemical biology, cell biology, synthetic chemistry, and medicinal chemistry for the identification of Small-molecule Stabilizers of Protein-Protein Interactions (PPIs) as a novel class of therapeutic agents and basic research tool compounds. With this new technological approach we aim to address a number of unmet medical needs in the areas Cancer, Neurodegenerative Diseases (Alzheimer’s, Parkinson’s), Pulmonary Diseases, Inflammation and Metabolic Diseases (Diabetes).

 Deliverables

List of deliverables.
Career Development Plan Documents, reports 2020-04-07 20:06:56
Recruitment Documents, reports 2020-04-07 20:06:56
Researcher Declaration Documents, reports 2020-04-07 20:06:56

Take a look to the deliverables list in detail:  detailed list of TASPPI deliverables.

 Publications

year authors and title journal last update
List of publications.
2020 Francesco Bosica, Sebastian Andrei, João Filipe Neves, Peter Brandt, Anders Gunnarsson, Isabelle Landrieu, Christian Ottmann, Gavin O\'Mahony
Design Of Drug-Like Protein-Protein Interaction Stabilizers Guided By Chelation-Controlled Bioactive Conformation Stabilization
published pages: , ISSN: 0947-6539, DOI: 10.1002/chem.202001608
Chemistry - A European Journal 2020-04-24

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The information about "TASPPI" are provided by the European Opendata Portal: CORDIS opendata.

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