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A novel double-point intravascular diagnostic probe with continuous monitoring of the biomarker panel, dual oxygen tension PcvO2 and PcsO2, for clinical assessment of heart failure

Total Cost €


EC-Contrib. €






 Sniff-Nose project word cloud

Explore the words cloud of the Sniff-Nose project. It provides you a very rough idea of what is the project "Sniff-Nose" about.

muscle    intravascular    lower    curved    vena    dual    kimal    returning    first    2019    fluorescent    sheath    probe    feasibility    metabolic    solution    panel    geometry    monitoring    positions    pcvo2    market    thousand    hundred    withdrawals    pcso2    longer       returned    space    sales    global    time    situation    645    resp    competing    oxygen    optical    solutions    vascular    usability    customers    heart    anaesthesiologists    single    annual    trl    plc    venous    outside    cava    abnormal    rest    instead    save    performed    insertion    nose    biomarker    coronary    inserted    vitro    oxygenation    utilise    except    fiber    catheters    tension    probes    continuous    uk    literature    sinus    minimise    body    flows    rate    exist    point    2013    cardiologists    describes    labs    double    diagnostic    diameters    central    procedure    million    oximetry    saturation    intermittent    size    unmet    sniff    blood   

Project "Sniff-Nose" data sheet

The following table provides information about the project.


Organization address
address: ERTHALSTR. 12
postcode: 63739
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Project website
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-1-2015
 Funding Scheme SME-1
 Starting year 2015
 Duration (year-month-day) from 2015-09-01   to  2015-10-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

Sniff-Nose shall sniff the oxygen tension resp. saturation of venous blood at two positions of a probe – with curved geometry to achieve that – in the Vena Cava (where all the returning blood of the body except of the heart flows) and in the Coronary Sinus (where the returned blood of the heart flows). As an abnormal metabolic situation of the heart muscle e.g. at heart failure will result in lower oxygen tension in the coronary sinus than in the rest of the body, the coronary sinus oxygen tension resp. saturation in comparison to the central venous oxygen tension resp. saturation is the biomarker for heart failure assessment. Our novel double-point intravascular diagnostic probe with continuous monitoring of the biomarker panel, dual oxygen tension PcvO2 and PcsO2, will utilise the state-of-the-art single optical fluorescent fiber technology to minimise geometry and size, to save the space in the probe and to achieve usability (instead of double fiber technology as in partially competing products for each measurement point) with outside diameters which can be inserted into the Vena Cava. The needs of the customers exist as literature describes procedure solutions to measure oxygenation at the two vascular positions, but these procedure solutions result in intermittent blood withdrawals through the insertion sheath from the Vena Cava with a longer time to results. Technical feasibility assessment of our Sniff Nose solution has been performed in-vitro in our labs, TRL 3. The Sniff-Nose dual-oximetry diagnostic probe market can be estimated from the central venous catheters market, with a global market of $645 million in 2013 and an annual growth rate of 4.9% through 2019. From the capabilities of our UK distribution partner Kimal plc we will solve the unmet needs of the cardiologists and anaesthesiologists, and achieve over the first 5 years sales of several hundred thousand probes.

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The information about "SNIFF-NOSE" are provided by the European Opendata Portal: CORDIS opendata.

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