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microCrysFact SIGNED

Microfluidic Crystal Factories (μ-CrysFact): a breakthrough approach for crystal engineering

Total Cost €


EC-Contrib. €






Project "microCrysFact" data sheet

The following table provides information about the project.


Organization address
address: Raemistrasse 101
postcode: 8092

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 1˙814˙128 €
 EC max contribution 1˙814˙128 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2015-STG
 Funding Scheme ERC-STG
 Starting year 2016
 Duration (year-month-day) from 2016-09-01   to  2021-08-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

To study and understand the aggregation, nucleation, and/or self-assembly processes of crystalline matter is of crucial importance for research and applications in many disciplines. For example, understanding the formation of crystalline amyloid fibres could lead to advances in the treatment and prevention of both Alzheimer’s and Parkinson’s diseases, whereas controlling the process of crystal formation can play a significant role in obtaining chemicals and materials that are important for industry as well as society as a whole (e.g., drugs, superconductors, polarizers and/or frequency modulators).

Despite the impressive progress made in molecular engineering during the last few decades, the quest for a general tool-box technology to study, control and monitor crystallisation processes as well as to isolate metastable states (dynamic capture) is still incomplete. That is because crystalline assemblies are frequently investigated in their equilibrium form, driving the system to its minimum energy state. This methodology limits the emergence of new chemicals and crystals with advanced functionalities, and thus hampers advances in the field of materials engineering.

µ-CrysFact will develop tool-box technologies where diffusion-limited and kinetically controlled environments will be achieved during crystallisation and where the isolation of non-equilibrium species will be facilitated by pushing crystallisation processes out of equilibrium. In addition, µ-CrysFact’s technologies will be used to localise, integrate and chemically treat crystals with the aim of honing their functionality. This unprecedented approach has the potential to lead to the discovery of new materials with advanced functions and unique properties, thus opening new horizons in materials engineering research.


year authors and title journal last update
List of publications.
2018 Marcus Hoop, Claudio F. Walde, Raffaele Riccò, Fajer Mushtaq, Anastasia Terzopoulou, Xiang-Zhong Chen, Andrew J. deMello, Christian J. Doonan, Paolo Falcaro, Bradley J. Nelson, Josep Puigmartí-Luis, Salvador Pané
Biocompatibility characteristics of the metal organic framework ZIF-8 for therapeutical applications
published pages: 13-21, ISSN: 2352-9407, DOI: 10.1016/j.apmt.2017.12.014
Applied Materials Today 11 2019-07-08
2018 Angel Pérez del Pino, Arántzazu González-Campo, Sandra Giraldo, José Peral, Enikö György, Constantin Logofatu, Andrew J. deMello, Josep Puigmartí-Luis
Synthesis of graphene-based photocatalysts for water splitting by laser-induced doping with ionic liquids
published pages: 48-58, ISSN: 0008-6223, DOI: 10.1016/j.carbon.2017.12.116
Carbon 130 2019-07-08
2018 S. Sevim, A. Sorrenti, C. Franco, S. Furukawa, S. Pané, A. J. deMello, J. Puigmartí-Luis
Self-assembled materials and supramolecular chemistry within microfluidic environments: from common thermodynamic states to non-equilibrium structures
published pages: , ISSN: 0306-0012, DOI: 10.1039/C8CS00025E
Chemical Society Reviews 2019-07-08
2019 Frederik Kotz, Patrick Risch, Karl Arnold, Semih Sevim, Josep Puigmartí-Luis, Alexander Quick, Michael Thiel, Andrei Hrynevich, Paul D. Dalton, Dorothea Helmer, Bastian E. Rapp
Fabrication of arbitrary three-dimensional suspended hollow microstructures in transparent fused silica glass
published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-019-09497-z
Nature Communications 10/1 2019-04-13
2018 Salvador Pané, Josep Puigmartí-Luis, Christos Bergeles, Xiang-Zhong Chen, Eva Pellicer, Jordi Sort, Vanda Počepcová, Antoine Ferreira, Bradley J. Nelson
Imaging Technologies for Biomedical Micro- and Nanoswimmers
published pages: 1800575, ISSN: 2365-709X, DOI: 10.1002/admt.201800575
Advanced Materials Technologies 2019-04-13

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