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U-PGx SIGNED

Ubiquitous Pharmacogenomics (U-PGx): Making actionable pharmacogenomic data and effective treatment optimization accessible to every European citizen

Total Cost €

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EC-Contrib. €

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Partnership

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Project "U-PGx" data sheet

The following table provides information about the project.

Coordinator
ACADEMISCH ZIEKENHUIS LEIDEN 

Organization address
address: ALBINUSDREEF 2
city: LEIDEN
postcode: 2333 ZA
website: www.lumc.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Project website http://upgx.eu
 Total cost 14˙936˙613 €
 EC max contribution 14˙936˙613 € (100%)
 Programme 1. H2020-EU.3.1.6. (Health care provision and integrated care)
 Code Call H2020-PHC-2015-two-stage
 Funding Scheme RIA
 Starting year 2016
 Duration (year-month-day) from 2016-01-01   to  2020-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ACADEMISCH ZIEKENHUIS LEIDEN NL (LEIDEN) coordinator 2˙881˙388.00
2    BIO.LOGIS GENETIC INFORMATION MANAGEMENT GMBH DE (FRANKFURT) participant 2˙316˙125.00
3    MEDIZINISCHE UNIVERSITAET WIEN AT (WIEN) participant 1˙429˙783.00
4    KNMP HOLDING B.V. NL (DEN HAAG) participant 1˙136˙108.00
5    THE UNIVERSITY OF LIVERPOOL UK (LIVERPOOL) participant 1˙078˙330.00
6    PANEPISTIMIO PATRON EL (RIO PATRAS) participant 909˙375.00
7    CENTRO DI RIFERIMENTO ONCOLOGICO DI AVIANO IT (AVIANO PN) participant 875˙380.00
8    SERVICIO ANDALUZ DE SALUD ES (SEVILLA) participant 810˙937.00
9    THE GOLDEN HELIX FOUNDATION UK (LONDON) participant 706˙250.00
10    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 665˙112.00
11    ROBERT BOSCH GESELLSCHAFT FUR MEDIZINISCHE FORSCHUNG MBH DE (STUTTGART) participant 561˙393.00
12    UNIVERZA V LJUBLJANI SI (LJUBLJANA) participant 430˙825.00
13    BUNDESINSTITUT FUR ARZNEIMITTEL UND MEDIZINPRODUKTE DE (BONN) participant 393˙125.00
14    UPPSALA UNIVERSITET SE (UPPSALA) participant 294˙583.00
15    UNIVERSITE PAUL SABATIER TOULOUSE III FR (TOULOUSE CEDEX 9) participant 280˙055.00
16    UNIVERSITAIR MEDISCH CENTRUM UTRECHT NL (UTRECHT) participant 159˙229.00
17    STICHTING SINT ANTONIUS ZIEKENHUIS NL (NIEUWEGEIN) participant 8˙610.00

Map

 Project objective

Pharmacogenomics is the study of genetic variability affecting an individual’s response to a drug. Its use allows personalized medicine and reduction in ‘trial and error’ prescribing leading to more efficacious, safer and cost-effective drug therapy. The U-PGx consortium will investigate a pre-emptive genotyping approach (that is: multiple pharmacogenomic variants are collected prospectively and embedded into the patients’ electronic record) of a panel of important pharmacogenomic variants as a new model of personalised medicine. To meet this goal we combine existing pharmacogenomics guidelines and novel health IT solutions. Implementation will be conducted at a large scale in seven existing European health care environments and accounts for the diversity in health system organisations and settings. Feasibility, health outcome and cost-effectiveness will be investigated. We will formulate European strategies for improving clinical implementation of pharmacogenomics based on the findings of this project.

 Deliverables

List of deliverables.
Organization of the 1st patient/general public oriented PGx information events Websites, patent fillings, videos etc. 2020-04-07 20:35:54
Organization of a U-PGx Personalized Medicine Day in France Websites, patent fillings, videos etc. 2020-04-07 20:35:53
Education programme for non-participants Websites, patent fillings, videos etc. 2020-04-07 20:35:54
Workshop for participating healthcare professionals Websites, patent fillings, videos etc. 2020-04-07 20:35:53
Report on predictions from first model Documents, reports 2020-04-07 20:35:54
updated version of DMP Open Research Data Pilot 2020-04-07 20:35:53
Organization of a U-PGx Personalized Medicine Day in the UK Websites, patent fillings, videos etc. 2020-04-07 20:35:53
2nd version of the public-domain web-based PGx information portal Other 2020-04-07 20:35:53
Summer school including ELSI topics (prepared by WP8) for medical and pharmacy students Websites, patent fillings, videos etc. 2020-04-07 20:35:53
Validated bioinformatics tool Other 2020-04-07 20:35:54
ELSI content for a summer school on PGx to be delivered by WP6 Demonstrators, pilots, prototypes 2020-04-07 20:35:53
Organization of a U-PGx Personalized Medicine Day in Sweden Websites, patent fillings, videos etc. 2020-04-07 20:35:54
Midterm Review Documents, reports 2020-04-07 20:35:54
Establishment of PK models for prediction of DDI and genetic polymorphisms on drug exposure for candidate genes included in the U-PGx trial Documents, reports 2020-04-07 20:35:54
Release of open-source software artefacts for decision support solutions Other 2020-04-07 20:35:52
first version of DMP Open Research Data Pilot 2020-04-07 20:35:52
PGx-guidelines therapeutic recommendations and risk-assessments in English Documents, reports 2020-04-07 20:35:52
set of specifications for the selected PGx assays Demonstrators, pilots, prototypes 2020-04-07 20:35:52
Report on models identified to be developed Documents, reports 2020-04-07 20:35:52
Report on detailed analysis of existing information infrastructures and requirements of implementation sites Documents, reports 2020-04-07 20:35:52
Survey to evaluate the state of PGx knowledge in the 7 participating countries Documents, reports 2020-04-07 20:35:52
Delivery of decision support solutions including framework for digital infrastructure including secure cloud solutions Other 2020-04-07 20:35:52
Standardized Electronic Case Record Form (eCRF) Other 2020-04-07 20:35:52
Organization of a U-PGx Personalized Medicine Day in Austria Websites, patent fillings, videos etc. 2020-04-07 20:35:52
1st version of the public-domain web-based U-PGx information portal Other 2020-04-07 20:35:52
Translated patient surveys for the web-based intensive monitoring system Documents, reports 2020-04-07 20:35:51
Organization of a U-PGx Personalized Medicine Day in Spain Websites, patent fillings, videos etc. 2020-04-07 20:35:52
Therapeutic recommendations in Dutch, Greek, German, Italian, Slovene and Spanish Documents, reports 2020-04-07 20:35:52
Promotional video will be produced that visualises and promotes the idea of the idea of personalised medicine and pre-emptive PGx testing Websites, patent fillings, videos etc. 2020-04-07 20:35:52
Report on ethical issues, guidelines, governance model and principals for patients included in U-PGx Documents, reports 2020-04-07 20:35:52
Dedicated webpage with secured login access for investigators and study staff Other 2020-04-07 20:35:52
eLearning program for the train the trainers concept Other 2020-04-07 20:35:52
Report on interoperability and development of a shared semantic model Documents, reports 2020-04-07 20:35:52
Analysis of European regulatory requirements Documents, reports 2020-04-07 20:35:52
List of relevant genetic variants for pre-emptive PGx testing Documents, reports 2020-04-07 20:35:52
Report on ELSI education needs Documents, reports 2020-04-07 20:35:52

Take a look to the deliverables list in detail:  detailed list of U-PGx deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Volker M. Lauschke, Magnus Ingelman-Sundberg
How to Consider Rare Genetic Variants in Personalized Drug Therapy
published pages: 745-748, ISSN: 0009-9236, DOI: 10.1002/cpt.976
Clinical Pharmacology & Therapeutics 103/5 2020-04-07
2018 Volker M. Lauschke, Isabel Barragan, Magnus Ingelman-Sundberg
Pharmacoepigenetics and Toxicoepigenetics: Novel Mechanistic Insights and Therapeutic Opportunities
published pages: 161-185, ISSN: 0362-1642, DOI: 10.1146/annurev-pharmtox-010617-053021
Annual Review of Pharmacology and Toxicology 58/1 2020-04-07
2018 Marin M. Jukić, Tore Haslemo, Espen Molden, Magnus Ingelman-Sundberg
Impact of CYP2C19 Genotype on Escitalopram Exposure and Therapeutic Failure: A Retrospective Study Based on 2,087 Patients
published pages: 463-470, ISSN: 0002-953X, DOI: 10.1176/appi.ajp.2017.17050550
American Journal of Psychiatry 175/5 2020-04-07
2017 María Santos, Mikko Niemi, Masahiro Hiratsuka, Masaki Kumondai, Magnus Ingelman-Sundberg, Volker M Lauschke, Cristina Rodríguez-Antona
Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics
published pages: 622-629, ISSN: 1098-3600, DOI: 10.1038/gim.2017.156
Genetics in Medicine 20/6 2020-04-07
2018 Rossana Roncato, Erika Cecchin, Giuseppe Toffoli
Improving decision making on DPYD and UGT1A1*28  patients’ profiling with an innovative reimbursement strategy
published pages: 301-304, ISSN: 1462-2416, DOI: 10.2217/pgs-2017-0303
Pharmacogenomics 19/4 2020-04-07
2018 George P Patrinos
Population pharmacogenomics: impact on public health and drug development
published pages: 3-6, ISSN: 1462-2416, DOI: 10.2217/pgs-2017-0166
Pharmacogenomics 19/1 2020-04-07
2018 Matthew P. Goetz, Katrin Sangkuhl, Henk-Jan Guchelaar, Matthias Schwab, Michael Province, Michelle Whirl-Carrillo, W. Fraser Symmans, Howard L. McLeod, Mark J. Ratain, Hitoshi Zembutsu, Andrea Gaedigk, Ron H. van Schaik, James N. Ingle, Kelly E. Caudle, Teri E. Klein
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy
published pages: 770-777, ISSN: 0009-9236, DOI: 10.1002/cpt.1007
Clinical Pharmacology & Therapeutics 103/5 2020-04-07
2018 Volker M. Lauschke, Lili Milani, Magnus Ingelman-Sundberg
Pharmacogenomic Biomarkers for Improved Drug Therapy—Recent Progress and Future Developments
published pages: , ISSN: 1550-7416, DOI: 10.1208/s12248-017-0161-x
The AAPS Journal 20/1 2020-04-07
2018 Kathrin Blagec, Rudolf Koopmann, Mandy Crommentuijn – van Rhenen, Inge Holsappel, Cathelijne H van der Wouden, Lidija Konta, Hong Xu, Daniela Steinberger, Enrico Just, Jesse J Swen, Henk-Jan Guchelaar, Matthias Samwald
Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project
published pages: 893-898, ISSN: 1067-5027, DOI: 10.1093/jamia/ocy005
Journal of the American Medical Informatics Association 25/7 2020-04-07
2017 Volker M. Lauschke, Maxim Ivanov, Magnus Ingelman-Sundberg
Pitfalls and Opportunities for Epigenomic Analyses Focused on Disease Diagnosis, Prognosis, and Therapy
published pages: 765-770, ISSN: 0165-6147, DOI: 10.1016/j.tips.2017.05.007
Trends in Pharmacological Sciences 38/9 2020-04-07
2017 Vasilios Fragoulakis, Christina Mitropoulou, Daphne Katelidou, Ron H. van Schaik, Nikolaos Maniadakis, George P. Patrinos
Performance Ratio Based Resource Allocation Decision-Making in Genomic Medicine
published pages: 67-73, ISSN: 1536-2310, DOI: 10.1089/omi.2016.0161
OMICS: A Journal of Integrative Biology 21/2 2020-04-07
2018 Thomas O. Bergmeijer, Jean-Luc Reny, Ruth E. Pakyz, Li Gong, Joshua P. Lewis, Eun-Young Kim, Daniel Aradi, Israel Fernandez-Cadenas, Richard B. Horenstein, Ming Ta Michael Lee, Ryan M. Whaley, Joan Montaner, Gian Franco Gensini, John H. Cleator, Kiyuk Chang, Lene Holmvang, Willibald Hochholzer, Dan M. Roden, Stefan Winter, Russ B. Altman, Dimitrios Alexopoulos, Ho-Sook Kim, Jean-Pierre Déry, Mein
Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points—Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC)
published pages: 152-159, ISSN: 0002-8703, DOI: 10.1016/j.ahj.2017.12.010
American Heart Journal 198 2020-04-07
2018 Ryoichi Fujiwara, Mathias Haag, Elke Schaeffeler, Anne T. Nies, Ulrich M. Zanger, Matthias Schwab
Systemic regulation of bilirubin homeostasis: Potential benefits of hyperbilirubinemia
published pages: 1609-1619, ISSN: 0270-9139, DOI: 10.1002/hep.29599
Hepatology 67/4 2020-04-07
2017 Rollinson V, Turner R, Pirmohamed M
Pharmacogenomics: an overview
published pages: , ISSN: 2053-6178, DOI: 10.1211/CP.2017.20203640
Clinical Pharmacist 2020-04-07
2018 Hannah Rieger, Patrik Schmidt, Elke Schaeffeler, Manabu Abe, Mira Schiffhauer, Matthias Schwab, Nicolas von Ahsen, Gabriela Zurek, Hartmut Kirchherr, Maria Shipkova, Eberhard Wieland
Validation of a high-performance liquid chromatography method for thiopurine S-methyltransferase activity in whole blood using 6-mercaptopurine as substrate
published pages: 803-809, ISSN: 1434-6621, DOI: 10.1515/cclm-2017-0670
Clinical Chemistry and Laboratory Medicine (CCLM) 56/5 2020-04-07
2018 Oliver Burk, Maria Kuzikov, Thales Kronenberger, Judith Jeske, Oliver Keminer, Wolfgang E. Thasler, Matthias Schwab, Carsten Wrenger, Björn Windshügel
Identification of approved drugs as potent inhibitors of pregnane X receptor activation with differential receptor interaction profiles
published pages: 1435-1451, ISSN: 0340-5761, DOI: 10.1007/s00204-018-2165-4
Archives of Toxicology 92/4 2020-04-07
2017 GP Patrinos, C Mitropoulou
Measuring the Value of Pharmacogenomics Evidence
published pages: 739-741, ISSN: 0009-9236, DOI: 10.1002/cpt.743
Clinical Pharmacology & Therapeutics 102/5 2020-04-07
2018 Theodora Katsila, Michalis Liontos, George P. Patrinos, Aristotelis Bamias, Dimitrios Kardamakis
The New Age of -omics in Urothelial Cancer – Re-wording Its Diagnosis and Treatment
published pages: 43-50, ISSN: 2352-3964, DOI: 10.1016/j.ebiom.2018.01.044
EBioMedicine 28 2020-04-07
2018 Elena De Mattia, Eva Dreussi, Marcella Montico, Sara Gagno, Chiara Zanusso, Luca Quartuccio, Salvatore De Vita, Michela Guardascione, Angela Buonadonna, Mario D’Andrea, Nicoletta Pella, Adolfo Favaretto, Enrico Mini, Stefania Nobili, Loredana Romanato, Erika Cecchin, Giuseppe Toffoli
A Clinical-Genetic Score to Identify Surgically Resected Colorectal Cancer Patients Benefiting From an Adjuvant Fluoropyrimidine-Based Therapy
published pages: , ISSN: 1663-9812, DOI: 10.3389/fphar.2018.01101
Frontiers in Pharmacology 9 2020-04-07
2018 Giuseppe Toffoli, Federico Innocenti, Jerry Polesel, Elena De Mattia, Franca Sartor, Chiara Dalle Fratte, Fabrizio Ecca, Eva Dreussi, Elisa Palazzari, Michela Guardascione, Angela Buonadonna, Luisa Foltran, Marica Garziera, Alessia Bignucolo, Stefania Nobili, Enrico Mini, Adolfo Favaretto, Massimiliano Berretta, Mario D\'Andrea, Antonino De Paoli, Rossana Roncato, Erika Cecchin
The Genotype for DPYD Risk Variants in Patients With Colorectal Cancer and the Related Toxicity Management Costs in Clinical Practice
published pages: , ISSN: 0009-9236, DOI: 10.1002/cpt.1257
Clinical Pharmacology & Therapeutics 2020-04-07
2018 Jun J. Yang, Michelle Whirl-Carrillo, Stuart A. Scott, Amy J. Turner, Matthias Schwab, Yoichi Tanaka, Guilherme Suarez-Kurtz, Elke Schaeffeler, Teri E. Klein, Neil A. Miller, Andrea Gaedigk
Pharmacogene Variation Consortium Gene Introduction: NUDT15
published pages: , ISSN: 0009-9236, DOI: 10.1002/cpt.1268
Clinical Pharmacology & Therapeutics 2020-04-07
2018 Malaz Gazzaz, Martina Kinzig, Elke Schaeffeler, Martin Jübner, Chih-hsuan Hsin, Xia Li, Max Taubert, Christina Trueck, Juliane Iltgen-Breburda, Daria Kraus, Christian Queckenberg, Marc Stoffel, Matthias Schwab, Fritz Sörgel, Uwe Fuhr
Drinking Ethanol Has Few Acute Effects on CYP2C9, CYP2C19, NAT2, and P-Glycoprotein Activities but Somewhat Inhibits CYP1A2, CYP2D6, and Intestinal CYP3A: So What?
published pages: 1249-1259, ISSN: 0009-9236, DOI: 10.1002/cpt.1083
Clinical Pharmacology & Therapeutics 104/6 2020-04-07
2018 Yitian Zhou, Reedik Mägi, Lili Milani, Volker M. Lauschke
Global genetic diversity of human apolipoproteins and effects on cardiovascular disease risk
published pages: 1987-2000, ISSN: 0022-2275, DOI: 10.1194/jlr.p086710
Journal of Lipid Research 59/10 2020-04-07
2018 Yitian Zhou, Volker M Lauschke
Comprehensive overview of the pharmacogenetic diversity in Ashkenazi Jews
published pages: 617-627, ISSN: 0022-2593, DOI: 10.1136/jmedgenet-2018-105429
Journal of Medical Genetics 55/9 2020-04-07
2018 Holger Fröhlich, Rudi Balling, Niko Beerenwinkel, Oliver Kohlbacher, Santosh Kumar, Thomas Lengauer, Marloes H. Maathuis, Yves Moreau, Susan A. Murphy, Teresa M. Przytycka, Michael Rebhan, Hannes Röst, Andreas Schuppert, Matthias Schwab, Rainer Spang, Daniel Stekhoven, Jimeng Sun, Andreas Weber, Daniel Ziemek, Blaz Zupan
From hype to reality: data science enabling personalized medicine
published pages: , ISSN: 1741-7015, DOI: 10.1186/s12916-018-1122-7
BMC Medicine 16/1 2020-04-07
2018 Konstantinos Assimakopoulos, Katerina Karaivazoglou, Maria Skokou, Marina Kalogeropoulou, Panagiotis Kolios, Philippos Gourzis, George Patrinos, Evangelia Tsermpini
Genetic Variations Associated with Sleep Disorders in Patients with Schizophrenia: A Systematic Review
published pages: 27, ISSN: 2305-6320, DOI: 10.3390/medicines5020027
Medicines 5/2 2020-04-07
2018 Yitian Zhou, Souren Mkrtchian, Masaki Kumondai, Masahiro Hiratsuka, Volker M. Lauschke
An optimized prediction framework to assess the functional impact of pharmacogenetic variants
published pages: , ISSN: 1470-269X, DOI: 10.1038/s41397-018-0044-2
The Pharmacogenomics Journal 2020-04-07
2018 Asan Agibetov, Kathrin Blagec, Hong Xu, Matthias Samwald
Fast and scalable neural embedding models for biomedical sentence classification
published pages: , ISSN: 1471-2105, DOI: 10.1186/s12859-018-2496-4
BMC Bioinformatics 19/1 2020-04-07
2019 Tore Haslemo, Erik Eliasson, Marin M. Jukić, Magnus Ingelman-Sundberg, Espen Molden
Significantly lower CYP2D6 metabolism measured as the O/N -desmethylvenlafaxine metabolic ratio in carriers of CYP2D6*41 versus CYP2D6*9 or CYP2D6*10 : a study on therapeutic drug monitoring data from 1003 genotyped Scandinavian patients
published pages: 194-201, ISSN: 0306-5251, DOI: 10.1111/bcp.13788
British Journal of Clinical Pharmacology 85/1 2020-04-07
2018 Irena Prodan Žitnik, Darko Černe, Irene Mancini, Lisa Simi, Mario Pazzagli, Chiara Di Resta, Helena Podgornik, Barbka Repič Lampret, Katarina Trebušak Podkrajšek, Csilla Sipeky, Ron van Schaik, Ivan Brandslund, Pieter Vermeersch, Matthias Schwab, Janja Marc
Personalized laboratory medicine: a patient-centered future approach
published pages: 1981-1991, ISSN: 1434-6621, DOI: 10.1515/cclm-2018-0181
Clinical Chemistry and Laboratory Medicine (CCLM) 56/12 2020-04-07
2019 Elke Schaeffeler, Simon U. Jaeger, Verena Klumpp, Jun J. Yang, Svitlana Igel, Laura Hinze, Martin Stanulla, Matthias Schwab
Impact of NUDT15 genetics on severe thiopurine-related hematotoxicity in patients with European ancestry
published pages: , ISSN: 1098-3600, DOI: 10.1038/s41436-019-0448-7
Genetics in Medicine 2020-04-07
2018 Yitian Zhou, Kohei Fujikura, Souren Mkrtchian, Volker M. Lauschke
Computational Methods for the Pharmacogenetic Interpretation of Next Generation Sequencing Data
published pages: , ISSN: 1663-9812, DOI: 10.3389/fphar.2018.01437
Frontiers in Pharmacology 9 2020-04-07
2019 Michael Ramharter, Matthias Schwab, Ghyslain Mombo-Ngoma, Rella Zoleko Manego, Daisy Akerey-Diop, Arti Basra, Jean-Rodolphe Mackanga, Heike Würbel, Jan-Georg Wojtyniak, Raquel Gonzalez, Ute Hofmann, Mirjam Geditz, Pierre-Blaise Matsiegui, Peter G. Kremsner, Clara Menendez, Reinhold Kerb, Thorsten Lehr
Population Pharmacokinetics of Mefloquine Intermittent Preventive Treatment for Malaria in Pregnancy in Gabon
published pages: e01113-18, ISSN: 0066-4804, DOI: 10.1128/aac.01113-18
Antimicrobial Agents and Chemotherapy 63/2 2020-04-07
2018 Erika Cecchin, Elena De Mattia, Fabrizio Ecca, Giuseppe Toffoli
Host genetic profiling to increase drug safety in colorectal cancer from discovery to implementation
published pages: 18-40, ISSN: 1368-7646, DOI: 10.1016/j.drup.2018.07.001
Drug Resistance Updates 39 2020-04-07
2018 Marin M Jukic, Volker M Lauschke, Takahiro Saito, Masahiro Hiratsuka, Magnus Ingelman-Sundberg
Functional characterization of CYP2D7 gene variants
published pages: 931-936, ISSN: 1462-2416, DOI: 10.2217/pgs-2018-0065
Pharmacogenomics 19/12 2020-04-07
2018 Magnus Ingelman-Sundberg, Souren Mkrtchian, Yitian Zhou, Volker M. Lauschke
Integrating rare genetic variants into pharmacogenetic drug response predictions
published pages: , ISSN: 1479-7364, DOI: 10.1186/s40246-018-0157-3
Human Genomics 12/1 2020-04-07
2018 Pascale Fisel, Elke Schaeffeler, Matthias Schwab
Clinical and Functional Relevance of the Monocarboxylate Transporter Family in Disease Pathophysiology and Drug Therapy
published pages: 352-364, ISSN: 1752-8054, DOI: 10.1111/cts.12551
Clinical and Translational Science 11/4 2020-04-07
2018 Theodora Katsila, George P. Patrinos, Dimitrios Kardamakis
Searching for Clinically Relevant Biomarkers in Geriatric Oncology
published pages: 1-7, ISSN: 2314-6133, DOI: 10.1155/2018/3793154
BioMed Research International 2018 2020-04-07
2019 Boyao Zhang, Volker M. Lauschke
Genetic variability and population diversity of the human SLCO (OATP) transporter family
published pages: 550-559, ISSN: 1043-6618, DOI: 10.1016/j.phrs.2018.10.017
Pharmacological Research 139 2020-04-07

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The information about "U-PGX" are provided by the European Opendata Portal: CORDIS opendata.

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