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Space and Motion SIGNED

Genetics and function of neuronal circuits controlling goal oriented movements

Total Cost €

0

EC-Contrib. €

0

Partnership

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Project "Space and Motion" data sheet

The following table provides information about the project.

Coordinator
UNITED KINGDOM RESEARCH AND INNOVATION 

There are not information about this coordinator. Please contact Fabio for more information, thanks.

 Coordinator Country United Kingdom [UK]
 Project website http://www.tripodilab.com
 Total cost 1˙495˙731 €
 EC max contribution 1˙495˙731 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2015-STG
 Funding Scheme ERC-STG
 Starting year 2016
 Duration (year-month-day) from 2016-01-01   to  2020-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNITED KINGDOM RESEARCH AND INNOVATION UK (SWINDON) coordinator 1˙495˙731.00
2    MEDICAL RESEARCH COUNCIL UK (SWINDON) coordinator 0.00

Map

 Project objective

With this proposal I plan to dissect, at the genetic level, those circuits controlling goal-oriented movements in mice. In particular, we will focus on the very feature that makes goal-oriented movements so unique in the world of motor control, the spatial awareness of such movements, the fact that their execution is likely to obey a precise metric. I want to understand: (1) which neuronal circuits promote the initiation of targeted-movement and assess the genetic heterogeneity of these circuits. (2) Characterise the function of genetically identified circuit elements during movement execution, with the aim of understanding how the metric of motion is encoded. (3) Investigate how sensory maps and motor maps are aligned during development and probe their plasticity. In prospective (4), we aim to understand how changes in such circuits impinge on the development and evolution of innate behaviours such as predation. The French mathematician Henry Poincaré wrote that ‘The real space is motor space’. Embedded in this idea is the intimate relation between the perceptual encoding of space and motor execution. Accordingly, our research starts at the motor level and aims to move to the perceptual level.

 Publications

year authors and title journal last update
List of publications.
2017 Toke P Krogager, Russell J Ernst, Thomas S Elliott, Laura Calo, Václav Beránek, Ernesto Ciabatti, Maria Grazia Spillantini, Marco Tripodi, Michael H Hastings, Jason W Chin
Labeling and identifying cell-specific proteomes in the mouse brain
published pages: 156-159, ISSN: 1087-0156, DOI: 10.1038/nbt.4056
Nature Biotechnology 36/2 2019-07-08
2014 J. Kohl, J. Ng, S. Cachero, E. Ciabatti, M.-J. Dolan, B. Sutcliffe, A. Tozer, S. Ruehle, D. Krueger, S. Frechter, T. Branco, M. Tripodi, G. S. X. E. Jefferis
Ultrafast tissue staining with chemical tags
published pages: E3805-E3814, ISSN: 0027-8424, DOI: 10.1073/pnas.1411087111
Proceedings of the National Academy of Sciences 111/36 2019-07-08
2017 Ernesto Ciabatti, Ana González-Rueda, Letizia Mariotti, Fabio Morgese, Marco Tripodi
Life-Long Genetic and Functional Access to Neural Circuits Using Self-Inactivating Rabies Virus
published pages: 382-392.e14, ISSN: 0092-8674, DOI: 10.1016/j.cell.2017.06.014
Cell 170/2 2019-07-08
2018 Jonathan J. Wilson, Nicolas Alexandre, Caterina Trentin, Marco Tripodi
Three-Dimensional Representation of Motor Space in the Mouse Superior Colliculus
published pages: 1744-1755.e12, ISSN: 0960-9822, DOI: 10.1016/j.cub.2018.04.021
Current Biology 28/11 2019-07-08

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "SPACE AND MOTION" project.

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Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

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The information about "SPACE AND MOTION" are provided by the European Opendata Portal: CORDIS opendata.

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