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CRADL SIGNED

Continuous Regional Analysis Device for neonate Lung

Total Cost €

0

EC-Contrib. €

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Partnership

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Project "CRADL" data sheet

The following table provides information about the project.

Coordinator
MIDDLESEX UNIVERSITY HIGHER EDUCATION CORPORATION 

Organization address
address: THE BURROUGHS, HENDON .
city: LONDON
postcode: NW4 4BT
website: http://www.mdx.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website http://cradlproject.org/
 Total cost 5˙537˙142 €
 EC max contribution 4˙234˙330 € (76%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-PHC-2015-two-stage
 Funding Scheme RIA
 Starting year 2016
 Duration (year-month-day) from 2016-01-01   to  2019-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    MIDDLESEX UNIVERSITY HIGHER EDUCATION CORPORATION UK (LONDON) coordinator 997˙500.00
2    UNIVERSITY COLLEGE LONDON UK (LONDON) participant 1˙067˙302.00
3    STUDIO FIFIELD SRL IT (MILANO) participant 584˙062.00
4    CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL DE (KIEL) participant 514˙690.00
5    LINNEUNIVERSITETET SE (VAXJO) participant 355˙025.00
6    ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM NL (AMSTERDAM) participant 323˙750.00
7    FILANTHROPIKO IDRYMA VIOIATRIKON EREVNON CY (LEFKOSIA) participant 162˙500.00
8    Ministry of Health of the Republic of Cyprus CY (Nicosia) participant 137˙500.00
9    PANAXEA BV NL (AMSTERDAM) participant 92˙000.00
10    SENTEC AG CH (THERWIL) participant 0.00
11    SWISSTOM AG CH (LANDQUART) participant 0.00
12    UNIVERSITE DE GENEVE CH (GENEVE) participant 0.00

Map

 Project objective

Each year 15 million babies are born prematurely and many suffer from respiratory failure due to immaturity of the lung and lack of control of breathing. Although respiratory support, especially mechanical ventilation, can improve their survival, it also causes severe injury to the vulnerable lung resulting in severe and chronic pulmonary morbidity lasting in to adulthood. Heterogeneity of lung aeration, resulting in areas of lung over inflation and lung collapse, plays a crucial part in the risk of mortality and morbidity due to respiratory failure. This distribution of lung aeration cannot be detected by currently available bedside monitoring tools and imaging methods. Thus, an imaging technique for continuous non-invasive bedside monitoring of infants lung function is urgently needed. In order to address this, CRADL will use EIT technology to establish a monitoring tool for interventions in the paediatric population. Electrical impedance tomography (EIT) is a non-radiative, inexpensive technique that can facilitate real time dynamic monitoring of lung aeration, and recent studies have shown that it is effective in monitoring aeration in preterm babies. CRADL will show how EIT can provide new cost effective, easy to use, respiratory management tools and clinical protocols that can be universally adopted to reduce deaths and disability in preterm babies by delivering a tool that provides continuous, non-invasive, radiation free, bedside information on regional lung aeration and ventilation during daily clinical care of (preterm) infants and children with respiratory failure. CRADL will also assess the effectiveness, efficacy and safety of such a system in guiding respiratory management and supportive care of the most common causes of paediatric respiratory failure (respiratory distress syndrome, bronchiolitis and acute respiratory distress syndrome), with the final goal of reducing short and long term adverse effects of disease and its treatment in this populat

 Deliverables

List of deliverables.
Validation of ability of EIT monitoring to detect adverse pulmonary effects associated with high ventilation heterogeneity Documents, reports 2019-10-15 13:17:15
Increased user base of this technology Other 2019-10-15 13:17:16
Wearable jacket with new microelectronic chips Demonstrators, pilots, prototypes 2019-10-15 13:17:19
Contributions to EIT and EIDORS websites Websites, patent fillings, videos etc. 2019-10-15 13:17:20
Optimised interface design for clinical users Other 2019-10-15 13:17:13
Clinical users trained in the application of current Swisscom clinical system and the pediatric version containing improvements made by the project. Websites, patent fillings, videos etc. 2019-10-15 13:17:18
Website creation Websites, patent fillings, videos etc. 2019-08-06 19:07:22

Take a look to the deliverables list in detail:  detailed list of CRADL deliverables.

 Publications

year authors and title journal last update
List of publications.
2017 Yu Wu, Dai Jiang, Andy Bardill, Serena De Gelidi, Richard Bayford, Andreas Demosthenous
Live Demonstration: A Wearable EIT System Using Active Electrodes for Monitoring Respiration
published pages: , ISSN: , DOI: 10.5281/zenodo.557093
2019-08-06
2017 Serena de Gelidi, Andy Bardill, Yu Wu, Andreas Demosthenous, Andrew Tizzard, Richard Bayford
Torso shape detection to improve lung monitoring
published pages: , ISSN: , DOI:
2019-08-06
2016 Richard Bayford, Andrew Tizzard, Inéz Frerichs, Norbert Weiler, Christina Karaoli, Stelios Christofides, Charalambos Yiannakkaras, Peter Rimensberger, Sven Nordebo, Stephan H. Böhm, Anton van Kaam, Bruce Fifield, Christopher Knox, Lotte Steuten, Gimon de Graaf, Rebecca Yerworth, Micheal Butterworth, Andreas Demosthenous
Continuous Regional Analysis Device for Neonatal Lung (CRADL)
published pages: 172-172, ISSN: , DOI: 10.1007/978-3-319-32703-7_35
2019-08-06
2017 D. Khodadad, S. Nordebo, N. Seifnaraghi, A. Waldmann, B. Muller, R. Bayford
Breath detection using short-time Fourier transform analysis in Electrical Impedance Tomography
published pages: 2185-2187, ISSN: , DOI:
32nd URSI General Assembly & Scientific Symposium 2019-08-06
2017 Yerworth RJ, Bayford R
DICOM for EIT presentation at the 18th International Conference on Biomedical Applications of Electrical Impedance Tomography
published pages: , ISSN: , DOI:
2019-08-06
2019 A Shiraz, D Khodadad, S Nordebo, R Yerworth, I Frerichs, A van Kaam, M Kallio, T Papadouri, R Bayford, A Demosthenous
Compressive sensing in electrical impedance tomography for breathing monitoring
published pages: 34010, ISSN: 1361-6579, DOI: 10.1088/1361-6579/ab0daa
Physiological Measurement 40/3 2019-08-06
2019 Marika Rahtu, Inéz Frerichs, Andreas D Waldmann, Claas Strodthoff, Tobias Becher, Richard Bayford, Merja Kallio
Early Recognition of Pneumothorax in Neonatal RDS with Electrical Impedance Tomography
published pages: , ISSN: 1073-449X, DOI: 10.1164/rccm.201810-1999im
American Journal of Respiratory and Critical Care Medicine 2019-08-06
2018 Nima Seifnaraghi, Andrew Tizzard, Serena de Gelidi, Davood Khodadad, Sven Nordebo, Anton van Kaam, Inéz Frerichs, Andreas Waldmann, Erich Sorantin, Sebastian Tschauner, Andreas Demosthenous, Richard Bayford
Effect of Thorax Deformation during Neonatal Lung EIT
published pages: , ISSN: , DOI:
2019-08-06
2017 Nima Seifnaraghi ,Andrew Tizzard, Serena de Gelidi, Davood Khodadad, Sven Nordebo, Anton Van Kaam, Inez Frerichs, Andreas Waldmann, Erich Sorantin, Sebastian Tschauner, Andreas Demosthenous, Stelios Christofides, Richard Bayford
Estimation of Thorax Shape for Forward Modelling in Lungs EIT
published pages: , ISSN: , DOI:
2019-08-06
2018 C Strodthoff
Effect of suctioning on chest EIT findings in neonates: preliminary results of a multicentre clinical study
published pages: , ISSN: , DOI:
2019-08-06
2019 Inez Frerichs
Electrical impedance tomography for monitoring regional lung ventilation in critically ill patients.
published pages: , ISSN: , DOI:
2019-08-06
2019 A. Dupré, M-R. Benissa, B. Müller, A. D. Waldmann, R. Yerworth, T. Becher, M. Miedema, S. Nordebo, D. Khodadad, I. Frerichs, R. Bayford, P. C. Rimensberger
Graphical user interface for patient data overview of long and continuous EIT monitoring for research analysis
published pages: , ISSN: , DOI:
2019-08-06
2018 Sven Nordebo, Mariana Dalarsson, Davood Khodadad, Beat Müller, Andreas D Waldmann, Tobias Becher, Inez Frerichs, Louiza Sophocleous, Daniel Sjöberg, Nima Seifnaraghi, Richard Bayford
A parametric model for the changes in the complex valued conductivity of a lung during tidal breathing
published pages: 205401, ISSN: 0022-3727, DOI: 10.1088/1361-6463/aabc04
Journal of Physics D: Applied Physics 51/20 2019-08-06
2016 Inéz Frerichs, Marcelo B P Amato, Anton H van Kaam, David G Tingay, Zhanqi Zhao, Bartłomiej Grychtol, Marc Bodenstein, Hervé Gagnon, Stephan H Böhm, Eckhard Teschner, Ola Stenqvist, Tommaso Mauri, Vinicius Torsani, Luigi Camporota, Andreas Schibler, Gerhard K Wolf, Diederik Gommers, Steffen Leonhardt, Andy Adler
Chest electrical impedance tomography examination, data analysis, terminology, clinical use and recommendations: consensus statement of the TRanslational EIT developmeNt stuDy group
published pages: 83-93, ISSN: 0040-6376, DOI: 10.1136/thoraxjnl-2016-208357
Thorax 72/1 2019-08-06
2019 Inez Frerichs
Electrical impedance tomography: The past, the present and the future.
published pages: , ISSN: , DOI:
2019-08-06
2019 David G. Tingay, Andreas D. Waldmann, Inéz Frerichs, Sarath Ranganathan, Andy Adler
Electrical Impedance Tomography Can Identify Ventilation and Perfusion Defects: A Neonatal Case
published pages: 384-386, ISSN: 1073-449X, DOI: 10.1164/rccm.201808-1551le
American Journal of Respiratory and Critical Care Medicine 199/3 2019-08-06
2018 S de Gelidi, N Seifnaraghi, A Bardill, A Tizzard, Y Wu, E Sorantin, S Nordebo, A Demosthenous, R Bayford
Torso shape detection to improve lung monitoring
published pages: 74001, ISSN: 1361-6579, DOI: 10.1088/1361-6579/aacc1c
Physiological Measurement 39/7 2019-08-06
2019 Inez Frerichs, Tobias Becher
Chest electrical impedance tomography measures in neonatology and paediatrics – a survey on clinical usefulness
published pages: , ISSN: 0967-3334, DOI: 10.1088/1361-6579/ab1946
Physiological Measurement 2019-08-06
2018 Tobias Becher and Inéz Frerichs
Clinical acceptance of various EIT parameters in neonatology and paediatrics: A systematic assessment of clinicians´ opinions
published pages: , ISSN: , DOI: 10.5281/zenodo.1210247
2019-08-06
2016 Y. Wu, P. Langlois, R. Bayford and A. Demosthenous
A novel active electrode IC for wearable EIT system
published pages: , ISSN: , DOI: 10.5281/zenodo.55753
2019-08-06
2018 Yu Wu, Dai Jiang, Andy Bardill, Serena de Gelidi, Richard Bayford, Andreas Demosthenous
A High Frame Rate Wearable EIT System Using Active Electrode ASICs for Lung Respiration and Heart Rate Monitoring
published pages: 3810-3820, ISSN: 1549-8328, DOI: 10.1109/tcsi.2018.2858148
IEEE Transactions on Circuits and Systems I: Regular Papers 65/11 2019-08-06
2018 Serena de Gelidi, Andy Bardill, Nima Seifnaraghi, Yu Wu, Inéz Frerichs, Andreas Demosthenous, Andrew Tizzard, Richard Bayford
Towards a thoracic conductive phantom for EIT
published pages: , ISSN: , DOI:
2019-08-06
2018 D Khodadad, S Nordebo, B Müller, A Waldmann, R Yerworth, T Becher, I Frerichs, L Sophocleous, A van Kaam, M Miedema, N Seifnaraghi, R Bayford
Optimized breath detection algorithm in electrical impedance tomography
published pages: 94001, ISSN: 1361-6579, DOI: 10.1088/1361-6579/aad7e6
Physiological Measurement 39/9 2019-08-06
2018 Marika Rahtu, Andreas D Waldmann, Esa Rahtu, Tobias Becher, Inéz Frerichs, Richard Bayford, Merja Kallio
Changes in ventilation distribution from pressure controlled ventilation to neutrally adjusted ventilator assist
published pages: , ISSN: , DOI:
2019-08-06
2018 L Sophocleous, I Frerichs, M Miedema, M Kallio, T Papadouri, C Karaoli, T Becher, D G Tingay, A H van Kaam, R Bayford, A D Waldmann
Clinical performance of a novel textile interface for neonatal chest electrical impedance tomography
published pages: 44004, ISSN: 1361-6579, DOI: 10.1088/1361-6579/aab513
Physiological Measurement 39/4 2019-08-06

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