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CRADL SIGNED

Continuous Regional Analysis Device for neonate Lung

Total Cost €

0

EC-Contrib. €

0

Partnership

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Project "CRADL" data sheet

The following table provides information about the project.

Coordinator
MIDDLESEX UNIVERSITY HIGHER EDUCATION CORPORATION 

Organization address
address: THE BURROUGHS, HENDON
city: LONDON
postcode: NW4 4BT
website: http://www.mdx.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 5˙537˙142 €
 EC max contribution 4˙234˙330 € (76%)
 Programme 1. H2020-EU.3.1. (SOCIETAL CHALLENGES - Health, demographic change and well-being)
 Code Call H2020-PHC-2015-two-stage
 Funding Scheme /RIA
 Starting year 2016
 Duration (year-month-day) from 2016-01-01   to  2018-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    MIDDLESEX UNIVERSITY HIGHER EDUCATION CORPORATION UK (LONDON) coordinator 997˙500.00
2    UNIVERSITY COLLEGE LONDON UK (LONDON) participant 1˙067˙302.00
3    STUDIO FIFIELD SRL IT (MILANO) participant 584˙062.00
4    CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL DE (KIEL) participant 514˙690.00
5    LINNEUNIVERSITETET SE (VAXJO) participant 355˙025.00
6    Academisch Medisch Centrum bij de Universiteit van Amsterdam NL (AMSTERDAM) participant 323˙750.00
7    FILANTHROPIKO IDRYMA VIOIATRIKON EREVNON CY (LEFKOSIA) participant 162˙500.00
8    Ministry of Health of the Republic of Cyprus CY (Nicosia) participant 137˙500.00
9    PANAXEA BV NL (AMSTERDAM) participant 92˙000.00
10    SWISSTOM AG CH (LANDQUART) participant 0.00
11    UNIVERSITE DE GENEVE CH (GENEVE) participant 0.00

Mappa

 Project objective

Each year 15 million babies are born prematurely and many suffer from respiratory failure due to immaturity of the lung and lack of control of breathing. Although respiratory support, especially mechanical ventilation, can improve their survival, it also causes severe injury to the vulnerable lung resulting in severe and chronic pulmonary morbidity lasting in to adulthood. Heterogeneity of lung aeration, resulting in areas of lung over inflation and lung collapse, plays a crucial part in the risk of mortality and morbidity due to respiratory failure. This distribution of lung aeration cannot be detected by currently available bedside monitoring tools and imaging methods. Thus, an imaging technique for continuous non-invasive bedside monitoring of infants lung function is urgently needed. In order to address this, CRADL will use EIT technology to establish a monitoring tool for interventions in the paediatric population. Electrical impedance tomography (EIT) is a non-radiative, inexpensive technique that can facilitate real time dynamic monitoring of lung aeration, and recent studies have shown that it is effective in monitoring aeration in preterm babies. CRADL will show how EIT can provide new cost effective, easy to use, respiratory management tools and clinical protocols that can be universally adopted to reduce deaths and disability in preterm babies by delivering a tool that provides continuous, non-invasive, radiation free, bedside information on regional lung aeration and ventilation during daily clinical care of (preterm) infants and children with respiratory failure. CRADL will also assess the effectiveness, efficacy and safety of such a system in guiding respiratory management and supportive care of the most common causes of paediatric respiratory failure (respiratory distress syndrome, bronchiolitis and acute respiratory distress syndrome), with the final goal of reducing short and long term adverse effects of disease and its treatment in this population.

 Work performed, outcomes and results:  advancements report(s) 

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