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ALGAE4A-B SIGNED

Development of Microalgae-based novel high added-value products for the Cosmetic and Aquaculture industry

Total Cost €

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EC-Contrib. €

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Partnership

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Project "ALGAE4A-B" data sheet

The following table provides information about the project.

Coordinator
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 

Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794
website: www.cnrs.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Project website http://www.algae4ab.eu
 Total cost 972˙000 €
 EC max contribution 972˙000 € (100%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2015
 Funding Scheme MSCA-RISE
 Starting year 2016
 Duration (year-month-day) from 2016-01-01   to  2019-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) coordinator 27˙000.00
2    FITOPLANCTON MARINO, S.L. ES (EL PUERTO DE SANTA MARIA) participant 234˙000.00
3    GEOPONIKO PANEPISTIMION ATHINON EL (ATHINA) participant 225˙000.00
4    APIVITA KALLYNTIKA DIAITITIKA FARMAKA ANONYMI EMPORIKI KAI VIOTECHNIKI ETAIREIA EL (MARKOPOULO) participant 216˙000.00
5    CENTRO DE CIENCIAS DO MAR DO ALGARVE PT (FARO) participant 108˙000.00
6    INSTITUTO ANDALUZ DE INVESTIGACIONY FORMACION AGRARIA PESQUERA ALIMENTARIA Y DE LA PRODUCCION ECOLOGICA ES (SEVILLA) participant 81˙000.00
7    LIFESEQUENCING SL ES (PATERNA) participant 81˙000.00

Map

 Project objective

Microalgae were always an exciting target for Aquaculture and Biotechnology, as they represent a largely untapped reservoir of novel and valuable bioactive compounds. ALGAE4A-B (ALGAE For Aquaculture and Beauty) project seeks to exploit the microalgae diversity, as a source for state-of-the art high-added-value biomolecules in aquaculture and cosmetics. The diversification of microalgae biomass production towards two independent applications will allow the microalgae industry to gain access to alternative markets in an uncertain, highly competitive and fast changing commercial environment. The project will combine both basic and applied multidisciplinary research in the fields of –omics technologies, biochemistry and applied biotechnology in order to: a) Develop and optimize of low input and application-based microalgae culture systems, b) Develop of “-omic” resources for both microalgae and fishes, c) Develop of downstream processing of high value added products from microalgae, with an emphasis in polysaccharides, proteins, enzymes, antioxidants, d) Develop, formulate and in vitro evaluate a new range of cosmetic and nutraceutical products for aquaculture. The implementation of the project will offer the industrial partners the opportunity to translate scientific research into well defined knowledge-based end products and analytical tools. Apart from scientific objectives the ALGAE4A-B will provide a platform for an efficient dissemination, transfer of knowledge and training between academic, commercial partners and society. Overall, ALGAE4A-B aspires to foster both the European capacity building and the strategic objectives of EU Blue Growth and Marine Biotechnology to harness the untapped potential of Europe's seas and coasts for training and sustainable growth.

 Deliverables

List of deliverables.
Final project evaluation and assessment report Documents, reports 2020-03-24 13:09:37
Progress reports and project evaluation and assessment reports Documents, reports 2020-03-24 13:09:32
Intellectual property and networking activities report Documents, reports 2020-03-24 13:09:35
Report on outreach activities to the general public Documents, reports 2020-03-24 13:09:39
Publications in scientific journals/conferences Other 2020-03-24 13:09:36
Detailed report on the training and transfer of knowledge obtained through the secondments Documents, reports 2020-03-13 11:19:22
Report on the quality control of the cosmeceutical products Documents, reports 2020-03-13 11:19:16
Establish the main biological effects of novel nutraceuticals on fish performance Documents, reports 2020-03-13 11:19:00
Purification and structural analysis of selected algae polysaccharides Documents, reports 2020-03-13 10:23:04
A downstream processing protocol for enzymes purification Documents, reports 2020-03-13 10:23:04
Establish protocols for nutraceuticals administration Documents, reports 2020-03-13 10:23:03
Purification and characterization of hatching enzyme Documents, reports 2020-03-13 10:23:04
Steady-state kinetic characterization of enzymes and thermodynamics analysis of the enzyme stability Documents, reports 2020-03-13 10:23:05
Define the ontogeny of immune barriers and effects of nutraceuticals Documents, reports 2020-03-13 11:19:08
Optimal conditions of light intensity Documents, reports 2020-03-11 13:05:56
Stimulation of growth by methanol Documents, reports 2020-03-11 14:34:51
Mapping bioactive properties using in vitro enzyme bioassays Documents, reports 2020-03-11 13:05:41
Glycomic profile of microalgae under different culture regimes Documents, reports 2020-03-11 13:05:41
Optimization of growth under various growth media Documents, reports 2020-03-11 13:05:56
Transcriptome associated with novel bioactive products in fish Documents, reports 2020-03-11 14:46:35
Progress report Month 36 Documents, reports 2020-03-11 14:34:39
Catalomic profile of microalgae under different culture regimes Documents, reports 2020-03-11 14:45:42
Minutes of all managements meetings held Documents, reports 2020-03-11 14:34:50
Development of a fish epithelial model and assessment of toxicity and impact on the transcriptome and enzyme activities of microalgal extracts Documents, reports 2020-03-11 13:05:55
Optimal conditions of photonic quality Documents, reports 2020-03-11 14:34:40
Analytical Handbook Other 2020-03-11 14:34:51
Identification and characterization of high-value added enzymes (proteases, lipases and antioxidant enzymes) with potential applications in cosmetology Documents, reports 2020-03-11 13:05:56
In vitro toxicity assessments of microalgae extracts or compounds Documents, reports 2020-03-11 13:05:55
Transcriptome associated with novel bioactive products in microalgae Documents, reports 2020-03-11 14:45:42
Proceedings of the Summer schools Documents, reports 2020-03-11 14:34:50
Comparative model of human and fish keratinocyte response to microalgal extracts Documents, reports 2020-03-11 13:05:54
Transfer of the optimal growth conditions from lab scale to the large scale photobioreactors Documents, reports 2020-03-11 14:34:51
Metabolomic profile of microalgae under different culture regimes Documents, reports 2020-03-11 13:05:38
Biannual e-newsletters Other 2020-03-11 14:34:51
Proceedings of the training workshops Documents, reports 2020-03-11 14:34:50
Report on the effect of microalgae extracts or compounds on the transcription of skin-related genes using human cell lines. Documents, reports 2020-03-11 13:05:54
ALGAE4A-B Project Website Websites, patent fillings, videos etc. 2020-01-29 12:55:50
Training and e-learning web-site Websites, patent fillings, videos etc. 2020-01-29 12:55:50
Progress report Month 12 Documents, reports 2020-01-29 12:55:50

Take a look to the deliverables list in detail:  detailed list of ALGAE4A-B deliverables.

 Publications

year authors and title journal last update
List of publications.
2020 Maria Patelou, Carlos Infante, Flavien Dardelle, Dörte Randewig, Evangelia D. Kouri, Michael K. Udvardi, Eleni Tsiplakou, Lalia Mantecón, Emmanouil Flemetakis
Transcriptomic and metabolomic adaptation of Nannochloropsis gaditana grown under different light regimes
published pages: 101735, ISSN: 2211-9264, DOI: 10.1016/j.algal.2019.101735
Algal Research 45 2020-02-28
2020 Sophia Letsiou, Rute Felix, João C. Cardoso, Liliana Anjos, Ana L. Mestre, Henirique L. Gomes, Deborah M. Power
Cartilage acidic protein 1 promotes increased cell viability, cell proliferation and energy metabolism in primary human dermal fibroblasts
published pages: , ISSN: 0300-9084, DOI: 10.1016/j.biochi.2020.02.008
Biochimie 2020-02-28
2018 Manuel Manchado
Genomic and epigenetic advances in sole aquaculture
published pages: , ISSN: , DOI:
2020-02-28
2019 Carlos Carballo, Patricia I.S. Pinto, Ana Patricia Mateus, Concha Berbel, Cláudia C. Guerreiro, Juan F. Martinez-Blanch, Francisco M. Codoñer, Lalia Mantecon, Deborah M. Power, Manuel Manchado
Yeast β-glucans and microalgal extracts modulate the immune response and gut microbiome in Senegalese sole (Solea senegalensis)
published pages: 31-39, ISSN: 1050-4648, DOI: 10.1016/j.fsi.2019.05.044
Fish & Shellfish Immunology 92 2020-02-28
2018 Pinto PIS, Guerreiro C, Costa RA, Martinez-Blanch JF, Carballo C, Codoñer F, Manchado M, Power DM
Omics signatures of pseudo-albino in Senegalese sole
published pages: , ISSN: , DOI:
VII Congress of the Iberian Soc. for Ichthyology 2020-02-28
2019 P. Pinto (CCMAR)
The use of fish mineralized tissues to assess estrogenic endocrine disruption and other ongoing transcriptome and microbiome studies at CCMAR (including Algae4ab)
published pages: , ISSN: , DOI:
Invited talk at research centre UMR I-02 SEBIO, University le Havre-Normandie (France) 2020-02-28
2020 C. Carballo
Genetic estimates and immune response associated with the Lymphocystis Disease Virus (LCDV) in marine fish
published pages: , ISSN: , DOI:
2020-02-28
2017 Joana Firmino, Carlos Carballo, Paula Armesto, Marco A. Campinho, Deborah M. Power, Manuel Manchado
Phylogeny, expression patterns and regulation of DNA Methyltransferases in early development of the flatfish, Solea senegalensis
published pages: , ISSN: 1471-213X, DOI: 10.1186/s12861-017-0154-0
BMC Developmental Biology 17/1 2020-01-29
2017 Anjos L, Cardoso JCR, Gardikis K, Power DM and Letsiou S
In vitro effects of Cartilage acidic protein 1 on primary human dermal fibroblasts
published pages: , ISSN: , DOI:
10th European Conferenceon Marine Natural Products proceedings 2020-01-29
2018 Konstantinos Gardikis, Sophia Letsiou
Marine products as effective raw materials for cosmetics – a research and innovation approach
published pages: , ISSN: , DOI:
30th International Symposium on the Chemistry of Natural Products 2020-01-29
2018 Konstantinos Gardikis, Manuel Manchado, Israel Guerrero-Cózar, Claudia Maya, Carlos Infante, Sophia Letsiou, Vasiliki-Ioanna Boka, William Helbert
Chrysolaminarin encapsulation in cyclodextrins and hydrolyzed rice flour. In vitro and in vivo efficacy studies on human dermal fibroblasts and fish larvae
published pages: , ISSN: , DOI:
BIT’s 8th Annual International Symposium of Drug Delivery Systems (SDDS-2018) 2020-01-29
2017 Carballo C.1*, Chronopoulou E.2, Crespo A.1, Gardikis K.3, Labrou N.2, Manchado M.
CHARACTERIZATION OF HATCHING ENZYMES IN SOLE (S. SENEGALENSIS) BY USING GENOMIC APPROACHES TO BE USED AS A NEW BIOTECHNOLOGICAL PRODUCT
published pages: , ISSN: , DOI:
International Flatfish Symposium 2017 2020-01-29
2018 Ana Manuela Crespo1, Carlos Carballo1, Lalia Mantecón2y Manuel Manchado1
LA REPROGRAMACION EPIGENÉTICA CON EXTRACTOS DE MICROALGAS MODIFICA LA TOLERANCIA A LA TEMPERATURA EN LARVAS DE LENGUADO
published pages: , ISSN: , DOI:
2020-01-29
2017 Ioanna Anastasiou, Sophia Letsiou, Katerina I. Kalliampakou, Carlos Infante , William Helbert, Kostantinos Gardikis, Lalia Mantecón and Emmanouil Flemetakis
In vitro antioxidant and wound healing effects of cyanobacteria exopolysaccharides on primary human fibroblasts
published pages: , ISSN: , DOI:
Proceedings of the 68th Helenic Biochemistry and Molecular Biology Society 2020-01-29
2018 Patrícia Pinto, C Carballo, AP Mateus, J Martinez-Blanch, F Codoner, L Mantecon, M Manchado, DM Power
Microalgal polysaccharide extracts modulate the immune response and microbiome in the gut of Senegalese sole (Solea Senegalensis)
published pages: , ISSN: , DOI:
31th New European Soc. for Comparative Physiology and Biochemistry (ESCPB 2018) 2020-01-29
2018 Carlos Carballo, Evangelia G. Chronopoulou, Sofia Letsiou, Claudia Maya, Nikolaos E. Labrou, Carlos Infante, Deborah M. Power, Manuel Manchado
Antioxidant capacity and immunomodulatory effects of a chrysolaminarin-enriched extract in Senegalese sole
published pages: 1-8, ISSN: 1050-4648, DOI: 10.1016/j.fsi.2018.07.052
Fish & Shellfish Immunology 82 2020-01-29
2017 Ioanna Anastasiou, Katerina I. Kalliampakou, Sophia Letsiou, Carlos Infante , William Helbert, Kostantinos Gardikis, Lalia Mantecon and Emmanouil Flemetakis.
In vitro effects of cyanobacteria exopolysaccharides on primary human dermal cells
published pages: , ISSN: , DOI:
10th European Conferenceon Marine Natural Products proceedings 2020-01-29
2018 Félix RC, Letsiou S, Anjos L, Gomes HL, Power DM
Electric Cell-substrate Impedance Sensing (ECIS) as a method to test marine bioactive compounds in wound healing
published pages: , ISSN: , DOI:
4th Conference on Impedance-Based Cell Assays (IBCA2018) 2020-01-29
2018 Patricia I.S. Pinto, Cláudia Guerreiro, Rita Costa, Juan F. Martinez-Blanch, Carlos Carballo, Francisco Codoñer, Manuel Manchado, Deborah M Power
Understanding pseudo-albinism in sole (Solea senegalensis): a transcriptomic and metagenomic approach
published pages: , ISSN: 2045-2322, DOI:
Scientific Reports 11-2018 2020-01-29
2018 Carlos Carballo, Evangelia G. Chronopoulou; Sofia Letsiou; Claudia Maya; Nikolaos E. Labrou; Carlos Infante; Deborah M. Power; Manuel Manchado
Estudio de las propiedades antioxidantes e inmunomoduladoras de la crisolaminarina
published pages: , ISSN: , DOI:
IX Jornadas de Acuicultura en el Litoral Suratlántico - La Acuicultura Progresa 2020-01-29

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