Explore the words cloud of the ComplexSex project. It provides you a very rough idea of what is the project "ComplexSex" about.
The following table provides information about the project.
|Coordinator Country||Sweden [SE]|
|Total cost||1˙492˙011 €|
|EC max contribution||1˙492˙011 € (100%)|
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
|Duration (year-month-day)||from 2016-05-01 to 2021-04-30|
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The origin and evolution of sexual reproduction and sex differences represents one of the major unsolved problems in evolutionary biology, and although much progress had been made both via theory and empirical research, recent data suggest that sex chromosome evolution may be more complex than previously thought. The concept of sexual antagonism (when there is a positive intersexual genetic correlation in trait expression but opposite fitness effects of the trait(s) in males and females) has become essential to our understanding of sex chromosome evolution. The goal of this proposal is to understand how the interacting effects of sexual antagonism, sex-linked genetic variation, and sex-specific selection shape the genetic architecture of complex traits. I will test the hypotheses that: 1) individual sexually antagonistic loci are common in the genome, both in separate-sexed species and in hermaphrodites, and drive patterns of sexual antagonism often seen on the trait level. 2) That the response to sex-specific selection in sex-linked loci is usually due to standing sexually antagonistic genetic variation. 3) That sexually antagonistic variation is primarily non-additive in nature. To accomplish this, I will use a combination of approaches, including sex-limited experimental evolution of the X chromosome and reciprocal sex chromosome introgression among distantly related populations of Drosophila, quantitative genetic analysis and experimental evolution mimicking the creation of a novel sex chromosome in the hermaphroditic flatworm Macrostomum, and analytical and simulation modeling. This project will serve to confirm or refute the assumption that trait-level sexual antagonism reflects the contributions of many individual sexually antagonistic loci, increase our understanding of the contribution of coevolution of the sex chromosomes to population divergence, and help provide us with a better general understanding of how genotype maps to phenotype.
|year||authors and title||journal||last update|
Colin Olito, Jessica K. Abbott, Crispin Y. Jordan
The interaction between sex-specific selection and local adaptation in species without separate sexes
published pages: 20170426, ISSN: 0962-8436, DOI: 10.1098/rstb.2017.0426
|Philosophical Transactions of the Royal Society B: Biological Sciences 373/1757||2019-04-02|
Anna K. NordÃ©n
Sex Chromosome Evolution in a Hermaphrodite: Genetic and phenotypic relationships between sex roles
published pages: , ISSN: , DOI:
Abbott, Jessica; MagalhÃ£es, Sara; Rodrigues, Leonor; Alpedrinha, Joao
Will Love Tear Them Apart? Identifying the Eco-Evolutionary Feedbacks of Sexual Traits
published pages: , ISSN: , DOI: 10.20944/PREPRINTS201808.0508.V1
Suvi Ponnikas, Hanna Sigeman, Jessica K. Abbott, Bengt Hansson
Why Do Sex Chromosomes Stop Recombining?
published pages: 492-503, ISSN: 0168-9525, DOI: 10.1016/j.tig.2018.04.001
|Trends in Genetics 34/7||2019-04-02|
Katrine Koch Lund-Hansen
Experimental Manipulation of Sexual Antagonism in Drosophila melanogaster
published pages: , ISSN: , DOI:
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