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inHForm SIGNED
Integrative omics of heart failure to inform discovery of novel drug targets and clinical biomarkers
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biobanks
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packages
cardiomyocyte
biomarkers
3000
investigator
discovery
therapeutic
clinical
risk
precision
dna
aging
muscle
translational
proteomic
profile
cells
therapy
endophenotypes
generations
underlying
causes
realize
pathophysiology
populations
pipeline
individually
myocardial
population
heritable
functional
anticipated
multitude
subjects
valvular
variants
assay
plasma
protein
medicine
strain
heart
builds
cohort
outcomes
genomics
nation
tailor
arising
complicated
promise
cohorts
microarrays
resequencing
spectrometry
genetic
samples
pathophysiological
microarray
registers
drug
epidemiology
6000
genomic
function
comorbidities
cardiac
human
components
profiling
genome
swedish
mechanisms
proteomics
epidemiological
morbidity
stage
mass
disease
insights
proteins
mortality
translate
expression
structure
Project "inHForm" data sheet
The following table provides information about the project.
| Coordinator |
LUNDS UNIVERSITET
Organization address contact info |
| Coordinator Country | Sweden [SE] |
| Project website | http://portal.research.lu.se/portal/en/persons/gustav-smith |
| Total cost | 1˙496˙625 € |
| EC max contribution | 1˙496˙625 € (100%) |
| Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
| Code Call | ERC-2015-STG |
| Funding Scheme | ERC-STG |
| Starting year | 2016 |
| Duration (year-month-day) | from 2016-04-01 to 2021-03-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | LUNDS UNIVERSITET | SE (Lund) | coordinator | 1˙496˙625.00 |
Map
Project objective
Heart failure is a leading cause of morbidity and mortality in the aging European populations. It is the end-stage of myocardial and valvular disease, arising from loss of viable or functional muscle cells in the heart. Therapy is complicated by the multitude of causes and comorbidities of heart failure. New therapeutic targets and clinical biomarkers to individually tailor therapy (‘precision medicine’) are greatly needed. This research program aims to realize the promise of precision medicine by applying an integrated proteomic, genomic and epidemiological approach to the underlying causes, mechanisms and consequences for heart failure. The program builds on unique Swedish nation-wide disease registers and large biobanks, the translational research profile of the investigator and experience in genomics, epidemiology and proteomics. The program includes five work packages: (1) comprehensive plasma protein profiling through a discovery pipeline including novel microarray-based methods and mass spectrometry in a population-based cohort of 6000 subjects and clinical cases to identify subjects at risk for heart disease (2) assessment of heritable components to outcomes in heart disease using nation-wide Swedish registers (3) genome-wide discovery of variants associated with risk of and outcomes in heart disease as well as endophenotypes for cardiac structure and function, using resequencing and DNA microarrays in large population-based cohorts including >70,000 subjects from three generations (4) expression profiling in human heart samples and a novel human cardiomyocyte strain assay to translate genomic and proteomic findings to understanding of pathophysiological mechanisms (5) evaluate the clinical importance of plasma proteins and genetic variants in >3000 clinical cases. This research program is anticipated to result in new insights into the pathophysiology of heart failure and discovery of drug targets and clinical biomarkers.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2018 |
Yan Borné, Klas Gränsbo, Jan Nilsson, Olle Melander, Marju Orho-Melander, J. Gustav Smith, Gunnar Engström Vascular Endothelial Growth Factor D, Pulmonary Congestion, and Incidence of Heart Failure published pages: 580-582, ISSN: 0735-1097, DOI: 10.1016/j.jacc.2017.11.058 |
Journal of the American College of Cardiology 71/5 | 2019-04-18 |
| 2017 |
Andreas Martinsson, Xinjun Li, Bengt Zöller, Pontus Andell, Charlotte Andersson, Kristina Sundquist, J. Gustav Smith Familial Aggregation of Aortic Valvular Stenosis published pages: , ISSN: 1942-3268, DOI: 10.1161/CIRCGENETICS.117.001742 |
Circulation: Cardiovascular Genetics 10/6 | 2019-04-18 |
| 2016 |
J. Gustav Smith, Janine F. Felix, Alanna C. Morrison, Andreas Kalogeropoulos, Stella Trompet, Jemma B. Wilk, Olof Gidlöf, Xinchen Wang, Michael Morley, Michael Mendelson, Roby Joehanes, Symen Ligthart, Xiaoyin Shan, Joshua C. Bis, Ying A. Wang, Marketa Sjögren, Julius Ngwa, Jeffrey Brandimarto, David J. Stott, David Aguilar, Kenneth M. Rice, Howard D. Sesso, Serkalem Demissie, Brendan M. Buckley, Kent D. Taylor, Ian Ford, Chen Yao, Chunyu Liu, Nona Sotoodehnia, Pim van der Harst, Bruno H. Ch. Stricker, Stephen B. Kritchevsky, Yongmei Liu, J. Michael Gaziano, Albert Hofman, Christine S. Moravec, André G. Uitterlinden, Manolis Kellis, Joyce B. van Meurs, Kenneth B. Margulies, Abbas Dehghan, Daniel Levy, Björn Olde, Bruce M. Psaty, L. Adrienne Cupples, J. Wouter Jukema, Luc Djousse, Oscar H. Franco, Eric Boerwinkle, Laurie A. Boyer, Christopher Newton-Cheh, Javed Butler, Ramachandran S. Vasan, Thomas P. Cappola, Nicholas L. Smith Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure published pages: e1006034, ISSN: 1553-7404, DOI: 10.1371/journal.pgen.1006034 |
PLOS Genetics 12/5 | 2019-04-18 |
| 2018 |
Carolina Roselli, Mark D. Chaffin, Lu-Chen Weng, Stefanie Aeschbacher, Gustav Ahlberg, Christine M. Albert, Peter Almgren, Alvaro Alonso, Christopher D. Anderson, Krishna G. Aragam, Dan E. Arking, John Barnard, Traci M. Bartz, Emelia J. Benjamin, Nathan A. Bihlmeyer, Joshua C. Bis, Heather L. Bloom, Eric Boerwinkle, Erwin B. Bottinger, Jennifer A. Brody, Hugh Calkins, Archie Campbell, Thomas P. Cappola, John Carlquist, Daniel I. Chasman, Lin Y. Chen, Yii-Der Ida Chen, Eue-Keun Choi, Seung Hoan Choi, Ingrid E. Christophersen, Mina K. Chung, John W. Cole, David Conen, James Cook, Harry J. Crijns, Michael J. Cutler, Scott M. Damrauer, Brian R. Daniels, Dawood Darbar, Graciela Delgado, Joshua C. Denny, Martin Dichgans, Marcus Dörr, Elton A. Dudink, Samuel C. Dudley, Nada Esa, Tonu Esko, Markku Eskola, Diane Fatkin, Stephan B. Felix, Ian Ford, Oscar H. Franco, Bastiaan Geelhoed, Raji P. Grewal, Vilmundur Gudnason, Xiuqing Guo, Namrata Gupta, Stefan Gustafsson, Rebecca Gutmann, Anders Hamsten, Tamara B. Harris, Caroline Hayward, Susan R. Heckbert, Jussi Hernesniemi, Lynne J. Hocking, Albert Hofman, Andrea R. V. R. Horimoto, Jie Huang, Paul L. Huang, Jennifer Huffman, Erik Ingelsson, Esra Gucuk Ipek, Kaoru Ito, Jordi Jimenez-Conde, Renee Johnson, J. Wouter Jukema, Stefan Kääb, Mika Kähönen, Yoichiro Kamatani, John P. Kane, Adnan Kastrati, Sekar Kathiresan, Petra Katschnig-Winter, Maryam Kavousi, Thorsten Kessler, Bas L. Kietselaer, Paulus Kirchhof, Marcus E. Kleber, Stacey Knight, Jose E. Krieger, Michiaki Kubo, Lenore J. Launer, Jari Laurikka, Terho Lehtimäki, Kirsten Leineweber, Rozenn N. Lemaitre, Man Li, Hong Euy Lim, Henry J. Lin, Honghuang Lin, Lars Lind, Cecilia M. Lindgren, Marja-Liisa Lokki, Barry London, Ruth J. F. Loos, Siew-Kee Low, Yingchang Lu, Leo-Pekka Lyytikäinen, Peter W. Macfarlane, Patrik K. Magnusson, Anubha Mahajan, Rainer Malik, Alfredo J. Mansur, Gregory M. Marcus, Lauren Margolin, Kenneth B. Margulies, Winfried März, David D. McManus, Olle Melander, Sanghamitra Mohanty, Jay A. Montgomery, Michael P. Morley, Andrew P. Morris, Martina Müller-Nurasyid, Andrea Natale, Saman Nazarian, Benjamin Neumann, Christopher Newton-Cheh, Maartje N. Niemeijer, Kjell Nikus, Peter Nilsson, Raymond Noordam, Heidi Oellers, Morten S. Olesen, Marju Orho-Melander, Sandosh Padmanabhan, Hui-Nam Pak, Guillaume Paré, Nancy L. Pedersen, Joanna Pera, Alexandre Pereira, David Porteous, Bruce M. Psaty, Sara L. Pulit, Clive R. Pullinger, Daniel J. Rader, Lena Refsgaard, Marta Ribasés, Paul M. Ridker, Michiel Rienstra, Lorenz Risch, Dan M. Roden, Jonathan Rosand, Michael A. Rosenberg, Natalia Rost, Jerome I. Rotter, Samir Saba, Roopinder K. Sandhu, Renate B. Schnabel, Katharina Schramm, Heribert Schunkert, Claudia Schurman, Stuart A. Scott, Ilkka Seppälä, Christian Shaffer, Svati Shah, Alaa A. Shalaby, Jaemin Shim, M. Benjamin Shoemaker, Joylene E. Siland, Juha Sinisalo, Moritz F. Sinner, Agnieszka Slowik, Albert V. Smith, Blair H. Smith, J. Gustav Smith, Jonathan D. Smith, Nicholas L. Smith, Elsayed Z. Soliman, Nona Sotoodehnia, Bruno H. Stricker, Albert Sun, Han Sun, Jesper H. Svendsen, Toshihiro Tanaka, Kahraman Tanriverdi, Kent D. Taylor, Maris Teder-Laving, Alexander Teumer, Sébastien Thériault, Stella Trompet, Nathan R. Tucker, Arnljot Tveit, Andre G. Uitterlinden, Pim Van Der Harst, Isabelle C. Van Gelder, David R. Van Wagoner, Niek Verweij, Efthymia Vlachopoulou, Uwe Völker, Biqi Wang, Peter E. Weeke, Bob Weijs, Raul Weiss, Stefan Weiss, Quinn S. Wells, Kerri L. Wiggins, Jorge A. Wong, Daniel Woo, Bradford B. Worrall, Pil-Sung Yang, Jie Yao, Zachary T. Yoneda, Tanja Zeller, Lingyao Zeng, Steven A. Lubitz, Kathryn L. Lunetta, Patrick T. Ellinor Multi-ethnic genome-wide association study for atrial fibrillation published pages: 1225-1233, ISSN: 1061-4036, DOI: 10.1038/s41588-018-0133-9 |
Nature Genetics 50/9 | 2019-04-18 |
| 2018 |
Grunde Gjesdal, Oscar Ö. Braun, J. Gustav Smith, Fredrik Scherstén, Patrik Tydén Blood lactate is a predictor of short-term mortality in patients with myocardial infarction complicated by heart failure but without cardiogenic shock published pages: , ISSN: 1471-2261, DOI: 10.1186/s12872-018-0744-1 |
BMC Cardiovascular Disorders 18/1 | 2019-04-18 |
| 2017 |
Philipp S. Wild, Janine F. Felix, Arne Schillert, Alexander Teumer, Ming-Huei Chen, Maarten J.G. Leening, Uwe Völker, Vera Großmann, Jennifer A. Brody, Marguerite R. Irvin, Sanjiv J. Shah, Setia Pramana, Wolfgang Lieb, Reinhold Schmidt, Alice V. Stanton, Dörthe Malzahn, Albert Vernon Smith, Johan Sundström, Cosetta Minelli, Daniela Ruggiero, Leo-Pekka Lyytikäinen, Daniel Tiller, J. Gustav Smith, Claire Monnereau, Marco R. Di Tullio, Solomon K. Musani, Alanna C. Morrison, Tune H. Pers, Michael Morley, Marcus E. Kleber, Jayashri Aragam, Emelia J. Benjamin, Joshua C. Bis, Egbert Bisping, Ulrich Broeckel, Susan Cheng, Jaap W. Deckers, Fabiola Del Greco M, Frank Edelmann, Myriam Fornage, Lude Franke, Nele Friedrich, Tamara B. Harris, Edith Hofer, Albert Hofman, Jie Huang, Alun D. Hughes, Mika Kähönen, KNHI investigators, Jochen Kruppa, Karl J. Lackner, Lars Lannfelt, Rafael Laskowski, Lenore J. Launer, Margrét Leosdottir, Honghuang Lin, Cecilia M. Lindgren, Christina Loley, Calum A. MacRae, Deborah Mascalzoni, Jamil Mayet, Daniel Medenwald, Andrew P. Morris, Christian Müller, Martina Müller-Nurasyid, Stefania Nappo, Peter M. Nilsson, Sebastian Nuding, Teresa Nutile, Annette Peters, Arne Pfeufer, Diana Pietzner, Peter P. Pramstaller, Olli T. Raitakari, Kenneth M. Rice, Fernando Rivadeneira, Jerome I. Rotter, Saku T. Ruohonen, Ralph L. Sacco, Tandaw E. Samdarshi, Helena Schmidt, Andrew S.P. Sharp, Denis C. Shields, Rossella Sorice, Nona Sotoodehnia, Bruno H. Stricker, Praveen Surendran, Simon Thom, Anna M. Töglhofer, André G. Uitterlinden, Rolf Wachter, Henry Völzke, Andreas Ziegler, Thomas Münzel, Winfried März, Thomas P. Cappola, Joel N. Hirschhorn, Gary F. Mitchell, Nicholas L. Smith, Ervin R. Fox, Nicole D. Dueker, Vincent W.V. Jaddoe, Olle Melander, Martin Russ, Terho Lehtimäki, Marina Ciullo, Andrew A. Hicks, Lars Lind, Vilmundur Gudnason, Burkert Pieske, Anthony J. Barron, Robert Zweiker, Heribert Schunkert, Erik Ingelsson, Kiang Liu, Donna K. Arnett, Bruce M. Psaty, Stefan Blankenberg, Martin G. Larson, Stephan B. Felix, Oscar H. Franco, Tanja Zeller, Ramachandran S. Vasan, Marcus Dörr Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function published pages: 1798-1812, ISSN: 0021-9738, DOI: 10.1172/JCI84840 |
Journal of Clinical Investigation 127/5 | 2019-04-18 |
| 2018 |
Mark D. Benson, Qiong Yang, Debby Ngo, Yineng Zhu, Dongxiao Shen, Laurie A. Farrell, Sumita Sinha, Michelle J. Keyes, Ramachandran S. Vasan, Martin G. Larson, J. Gustav Smith, Thomas J. Wang, Robert E. Gerszten Genetic Architecture of the Cardiovascular Risk Proteome published pages: 1158-1172, ISSN: 0009-7322, DOI: 10.1161/CIRCULATIONAHA.117.029536 |
Circulation 137/11 | 2019-04-18 |
| 2017 |
Pontus Andell, Xinjun Li, Andreas Martinsson, Charlotte Andersson, Martin Stagmo, Bengt Zöller, Kristina Sundquist, J Gustav Smith Epidemiology of valvular heart disease in a Swedish nationwide hospital-based register study published pages: 1696-1703, ISSN: 1355-6037, DOI: 10.1136/heartjnl-2016-310894 |
Heart 103/21 | 2019-04-18 |
| 2018 |
Andreas Martinsson, Petter Oest, Maj-Britt Wiborg, Öyvind Reitan, J. Gustav Smith Longitudinal evaluation of ventricular ejection fraction and NT-proBNP across heart failure subgroups published pages: 205-210, ISSN: 1401-7431, DOI: 10.1080/14017431.2018.1461920 |
Scandinavian Cardiovascular Journal 52/4 | 2019-04-18 |
| 2017 |
Stephen Zewinger, Marcus E Kleber, Vinicius Tragante, Raymond O McCubrey, Amand F Schmidt, Kenan Direk, Ulrich Laufs, Christian Werner, Wolfgang Koenig, Dietrich Rothenbacher, Ute Mons, Lutz P Breitling, Herrmann Brenner, Richard T Jennings, Ioannis Petrakis, Sarah Triem, Mira Klug, Alexandra Filips, Stefan Blankenberg, Christoph Waldeyer, Christoph Sinning, Renate B Schnabel, Karl J Lackner, Efthymia Vlachopoulou, Ottar Nygård, Gard Frodahl Tveitevåg Svingen, Eva Ringdal Pedersen, Grethe S Tell, Juha Sinisalo, Markku S Nieminen, Reijo Laaksonen, Stella Trompet, Roelof A J Smit, Naveed Sattar, J Wouter Jukema, Heinrich V Groesdonk, Graciela Delgado, Tatjana Stojakovic, Anna P Pilbrow, Vicky A Cameron, A Mark Richards, Robert N Doughty, Yan Gong, Rhonda Cooper-DeHoff, Julie Johnson, Markus Scholz, Frank Beutner, Joachim Thiery, J Gustav Smith, Ragnar O Vilmundarson, Ruth McPherson, Alexandre F R Stewart, Sharon Cresci, Petra A Lenzini, John A Spertus, Oliviero Olivieri, Domenico Girelli, Nicola I Martinelli, Andreas Leiherer, Christoph H Saely, Heinz Drexel, Axel Mündlein, Peter S Braund, Christopher P Nelson, Nilesh J Samani, Daniel Kofink, Imo E Hoefer, Gerard Pasterkamp, Arshed A Quyyumi, Yi-An Ko, Jaana A Hartiala, Hooman Allayee, W H Wilson Tang, Stanley L Hazen, Niclas Eriksson, Claes Held, Emil Hagström, Lars Wallentin, Axel Åkerblom, Agneta Siegbahn, Igor Karp, Christopher Labos, Louise Pilote, James C Engert, James M Brophy, George Thanassoulis, Peter Bogaty, Wojciech Szczeklik, Marcin Kaczor, Marek Sanak, Salim S Virani, Christie M Ballantyne, Vei-Vei Lee, Eric Boerwinkle, Michael V Holmes, Benjamin D Horne, Aroon Hingorani, Folkert W Asselbergs, Riyaz S Patel, Bernhard K Krämer, Hubert Scharnagl, Danilo Fliser, Winfried März, Thimoteus Speer Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study published pages: 534-543, ISSN: 2213-8587, DOI: 10.1016/S2213-8587(17)30096-7 |
The Lancet Diabetes & Endocrinology 5/7 | 2019-04-18 |
| 2017 |
Ihdina Sukma Dewi, Olof Gidlöf, Zsuzsanna Hollander, Karen K. Lam, Mark D. Benson, Oscar O. Braun, Johan Nilsson, Scott J. Tebbutt, Raymond T. Ng, Jenny Öhman, Bruce M. McManus, J. Gustav Smith Immunological Serum Protein Profiles for Noninvasive Detection of Acute Cellular Rejection After Heart Transplantation published pages: 2946-2947, ISSN: 0735-1097, DOI: 10.1016/j.jacc.2017.10.012 |
Journal of the American College of Cardiology 70/23 | 2019-04-18 |
| 2017 |
Ingrid E Christophersen, Michiel Rienstra, Carolina Roselli, Xiaoyan Yin, Bastiaan Geelhoed, John Barnard, Honghuang Lin, Dan E Arking, Albert V Smith, Christine M Albert, Mark Chaffin, Nathan R Tucker, Molong Li, Derek Klarin, Nathan A Bihlmeyer, Siew-Kee Low, Peter E Weeke, Martina Müller-Nurasyid, J Gustav Smith, Jennifer A Brody, Maartje N Niemeijer, Marcus Dörr, Stella Trompet, Jennifer Huffman, Stefan Gustafsson, Claudia Schurmann, Marcus E Kleber, Leo-Pekka Lyytikäinen, Ilkka Seppälä, Rainer Malik, Andrea R V R Horimoto, Marco Perez, Juha Sinisalo, Stefanie Aeschbacher, Sébastien Thériault, Jie Yao, Farid Radmanesh, Stefan Weiss, Alexander Teumer, Seung Hoan Choi, Lu-Chen Weng, Sebastian Clauss, Rajat Deo, Daniel J Rader, Svati H Shah, Albert Sun, Jemma C Hopewell, Stephanie Debette, Ganesh Chauhan, Qiong Yang, Bradford B Worrall, Guillaume Paré, Yoichiro Kamatani, Yanick P Hagemeijer, Niek Verweij, Joylene E Siland, Michiaki Kubo, Jonathan D Smith, David R Van Wagoner, Joshua C Bis, Siegfried Perz, Bruce M Psaty, Paul M Ridker, Jared W Magnani, Tamara B Harris, Lenore J Launer, M Benjamin Shoemaker, Sandosh Padmanabhan, Jeffrey Haessler, Traci M Bartz, Melanie Waldenberger, Peter Lichtner, Marina Arendt, Jose E Krieger, Mika Kähönen, Lorenz Risch, Alfredo J Mansur, Annette Peters, Blair H Smith, Lars Lind, Stuart A Scott, Yingchang Lu, Erwin B Bottinger, Jussi Hernesniemi, Cecilia M Lindgren, Jorge A Wong, Jie Huang, Markku Eskola, Andrew P Morris, Ian Ford, Alex P Reiner, Graciela Delgado, Lin Y Chen, Yii-Der Ida Chen, Roopinder K Sandhu, Man Li, Eric Boerwinkle, Lewin Eisele, Lars Lannfelt, Natalia Rost, Christopher D Anderson, Kent D Taylor, Archie Campbell, Patrik K Magnusson, David Porteous, Lynne J Hocking, Efthymia Vlachopoulou, Nancy L Pedersen, Kjell Nikus, Marju Orho-Melander, Anders Hamsten, Jan Heeringa, Joshua C Denny, Jennifer Kriebel, Dawood Darbar, Christopher Newton-Cheh, Christian Shaffer, Peter W Macfarlane, Stefanie Heilmann-Heimbach, Peter Almgren, Paul L Huang, Nona Sotoodehnia, Elsayed Z Soliman, Andre G Uitterlinden, Albert Hofman, Oscar H Franco, Uwe Völker, Karl-Heinz Jöckel, Moritz F Sinner, Henry J Lin, Xiuqing Guo, Martin Dichgans, Erik Ingelsson, Charles Kooperberg, Olle Melander, Ruth J F Loos, Jari Laurikka, David Conen, Jonathan Rosand, Pim van der Harst, Marja-Liisa Lokki, Sekar Kathiresan, Alexandre Pereira, J Wouter Jukema, Caroline Hayward, Jerome I Rotter, Winfried März, Terho Lehtimäki, Bruno H Stricker, Mina K Chung, Stephan B Felix, Vilmundur Gudnason, Alvaro Alonso, Dan M Roden, Stefan Kääb, Daniel I Chasman, Susan R Heckbert, Emelia J Benjamin, Toshihiro Tanaka, Kathryn L Lunetta, Steven A Lubitz, Patrick T Ellinor Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation published pages: 946-952, ISSN: 1061-4036, DOI: 10.1038/ng.3843 |
Nature Genetics 49/6 | 2019-04-18 |
| 2017 |
Steven A. Lubitz, Xiaoyan Yin, Henry J. Lin, Matthew Kolek, J. Gustav Smith, Stella Trompet, Michiel Rienstra, Natalia S. Rost, Pedro L. Teixeira, Peter Almgren, Christopher D. Anderson, Lin Y. Chen, Gunnar Engström, Ian Ford, Karen L. Furie, Xiuqing Guo, Martin G. Larson, Kathryn L. Lunetta, Peter W. Macfarlane, Bruce M. Psaty, Elsayed Z. Soliman, Nona Sotoodehnia, David J. Stott, Kent D. Taylor, Lu-Chen Weng, Jie Yao, Bastiaan Geelhoed, Niek Verweij, Joylene E. Siland, Sekar Kathiresan, Carolina Roselli, Dan M. Roden, Pim van der Harst, Dawood Darbar, J. Wouter Jukema, Olle Melander, Jonathan Rosand, Jerome I. Rotter, Susan R. Heckbert, Patrick T. Ellinor, Alvaro Alonso, Emelia J. Benjamin Genetic Risk Prediction of Atrial Fibrillation published pages: 1311-1320, ISSN: 0009-7322, DOI: 10.1161/CIRCULATIONAHA.116.024143 |
Circulation 135/14 | 2019-04-18 |
| 2017 |
Richard Petersson, J. Gustav Smith, David A. Larsson, Öyvind Reitan, Jonas Carlson, Pyotr Platonov, Fredrik Holmqvist Orthogonal P-wave morphology is affected by intra-atrial pressures published pages: , ISSN: 1471-2261, DOI: 10.1186/s12872-017-0724-x |
BMC Cardiovascular Disorders 17/1 | 2019-04-18 |
| 2017 |
Lu-Chen Weng, Seung Hoan Choi, Derek Klarin, J. Gustav Smith, Po-Ru Loh, Mark Chaffin, Carolina Roselli, Olivia L. Hulme, Kathryn L. Lunetta, Josée Dupuis, Emelia J. Benjamin, Christopher Newton-Cheh, Sekar Kathiresan, Patrick T. Ellinor, Steven A. Lubitz Heritability of Atrial Fibrillation published pages: , ISSN: 1942-3268, DOI: 10.1161/CIRCGENETICS.117.001838 |
Circulation: Cardiovascular Genetics 10/6 | 2019-04-18 |
| 2017 |
Francesca N. Delling, Xinjun Li, Shuo Li, Qiong Yang, Vanessa Xanthakis, Andreas Martinsson, Pontus Andell, Birgitta T. Lehman, Ewa W. Osypiuk, Plamen Stantchev, Bengt Zöller, Emelia J. Benjamin, Kristina Sundquist, Ramachandran S. Vasan, J. Gustav Smith Heritability of Mitral Regurgitation published pages: , ISSN: 1942-3268, DOI: 10.1161/CIRCGENETICS.117.001736 |
Circulation: Cardiovascular Genetics 10/5 | 2019-04-18 |
| 2018 |
Moman A. Mohammad, Sasha Koul, J. Gustav Smith, Marco Noc, Irene Lang, Michael Holzer, Peter Clemmensen, Ulf Jensen, Thomas Engstrøm, Håkan Arheden, Stefan James, Bertil Lindahl, Bernhard Metzler, David Erlinge Predictive Value of High-Sensitivity Troponin T for Systolic Dysfunction and Infarct Size (Six Months) After ST-Elevation Myocardial Infarction published pages: 735-743, ISSN: 0002-9149, DOI: 10.1016/j.amjcard.2018.05.005 |
The American Journal of Cardiology 122/5 | 2019-04-18 |
| 2018 |
Anna Helgadottir, Gudmar Thorleifsson, Solveig Gretarsdottir, Olafur A. Stefansson, Vinicius Tragante, Rosa B. Thorolfsdottir, Ingileif Jonsdottir, Thorsteinn Bjornsson, Valgerdur Steinthorsdottir, Niek Verweij, Jonas B. Nielsen, Wei Zhou, Lasse Folkersen, Andreas Martinsson, Mahyar Heydarpour, Siddharth Prakash, Gylfi Oskarsson, Tomas Gudbjartsson, Arnar Geirsson, Isleifur Olafsson, Emil L. Sigurdsson, Peter Almgren, Olle Melander, Anders Franco-Cereceda, Anders Hamsten, Lars Fritsche, Maoxuan Lin, Bo Yang, Whitney Hornsby, Dongchuan Guo, Chad M. Brummett, Gonçalo Abecasis, Michael Mathis, Dianna Milewicz, Simon C. Body, Per Eriksson, Cristen J. Willer, Kristian Hveem, Christopher Newton-Cheh, J. Gustav Smith, Ragnar Danielsen, Gudmundur Thorgeirsson, Unnur Thorsteinsdottir, Daniel F. Gudbjartsson, Hilma Holm, Kari Stefansson Genome-wide analysis yields new loci associating with aortic valve stenosis published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-018-03252-6 |
Nature Communications 9/1 | 2019-04-18 |
| 2016 |
Connie Wu, Pankaj Arora, Obiajulu Agha, Liam A. Hurst, Kaitlin Allen, Daniel I. Nathan, Dongjian Hu, Pawina Jiramongkolchai, J. Gustav Smith, Olle Melander, Sander Trenson, Stefan P. Janssens, Ibrahim Domian, Thomas J. Wang, Kenneth D. Bloch, Emmanuel S. Buys, Donald B. Bloch, Christopher Newton-Cheh Novel MicroRNA Regulators of Atrial Natriuretic Peptide Production published pages: 1977-1987, ISSN: 0270-7306, DOI: 10.1128/MCB.01114-15 |
Molecular and Cellular Biology 36/14 | 2019-04-18 |
| 2017 |
J. Gustav Smith Molecular Epidemiology of Heart Failure published pages: 757-769, ISSN: 2452-302X, DOI: 10.1016/j.jacbts.2017.07.010 |
JACC: Basic to Translational Science 2/6 | 2019-04-18 |
| 2018 |
Magnus P. Lindgren, MirNabi PirouziFard, J. Gustav Smith, Jan Sundquist, Kristina Sundquist, Bengt Zöller A Swedish Nationwide Adoption Study of the Heritability of Heart Failure published pages: 703, ISSN: 2380-6583, DOI: 10.1001/jamacardio.2018.1919 |
JAMA Cardiology 3/8 | 2019-04-18 |
| 2017 |
Mia N. Christiansen, Lars Køber, Peter Weeke, Ramachandran S. Vasan, Jørgen L. Jeppesen, J. Gustav Smith, Gunnar H. Gislason, Christian Torp-Pedersen, Charlotte Andersson Age-Specific Trends in Incidence, Mortality, and Comorbidities of Heart Failure in Denmark, 1995 to 2012 published pages: 1214-1223, ISSN: 0009-7322, DOI: 10.1161/CIRCULATIONAHA.116.025941 |
Circulation 135/13 | 2019-04-18 |
| 2017 |
J. Gustav Smith, Robert E. Gerszten Emerging Affinity-Based Proteomic Technologies for Large-Scale Plasma Profiling in Cardiovascular Disease published pages: 1651-1664, ISSN: 0009-7322, DOI: 10.1161/CIRCULATIONAHA.116.025446 |
Circulation 135/17 | 2019-06-19 |
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "INHFORM" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "INHFORM" are provided by the European Opendata Portal: CORDIS opendata.