Explore the words cloud of the GLYCOSENSE project. It provides you a very rough idea of what is the project "GLYCOSENSE" about.
The following table provides information about the project.
UNIVERSITY OF YORK
|Coordinator Country||United Kingdom [UK]|
|Total cost||258˙107 €|
|EC max contribution||258˙107 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2017-02-01 to 2020-01-31|
Take a look of project's partnership.
|1||UNIVERSITY OF YORK||UK (YORK NORTH YORKSHIRE)||coordinator||258˙107.00|
|2||THE UNIVERSITY OF SYDNEY||AU (SYDNEY)||partner||0.00|
Surfaces with the capacity for selective recognition of particular pathogens would offer great potential in a number of biomedical applications, including diagnostic devices. Mammalian cells are decorated with a carbohydrate-rich layer, the glycocalyx, which facilitates cellular recognition. Carbohydrate-binding proteins can interact with these sugar motifs to facilitate highly selective recognition, a strategy which is exploited by many viral and bacterial pathogens. Such species have evolved to display recognition units on their surfaces which may interact with considerable affinity with glycan structures displayed on cellular surfaces. This molecular recognition constitutes a key step in the processes of infection or toxicity, and is therefore an attractive target for the development of diagnostic devices. In this project, Dr Clare Mahon proposes to develop surface-tethered polymer brushes which will mimic the glycocalyx in terms of facilitating adhesion of pathogens. Through the incorporation of different fluorophores, the surfaces will be used to construct sensing arrays which will enable the rapid and cost-effective identification of water-borne pathogens and common respiratory pathogens.
|year||authors and title||journal||last update|
ThÃ©ophile Pelras, Clare S. Mahon, Nonappa, Olli Ikkala, AndrÃ© H. GrÃ¶schel, Markus MÃ¼llner
Polymer Nanowires with Highly Precise Internal Morphology and Topography
published pages: 12736-12740, ISSN: 0002-7863, DOI: 10.1021/jacs.8b08870
|Journal of the American Chemical Society 140/40||2020-04-14|
ThÃ©ophile Pelras, Clare S. Mahon, Markus MÃ¼llner
Synthesis and Applications of Compartmentalised Molecular Polymer Brushes
published pages: 6982-6994, ISSN: 1433-7851, DOI: 10.1002/anie.201711878
|Angewandte Chemie International Edition 57/24||2020-04-14|
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The information about "GLYCOSENSE" are provided by the European Opendata Portal: CORDIS opendata.
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