OXYTRAIN project deliverables
The page lists 10 deliverables related to the research project "OXYTRAIN".
List of Deliverables
| title and desprition | type | last update |
|---|---|---|
Generation and transfer of six SSB mutant libraries to the RWTH/TUG partners for screeningUsing technology of SSB, mutant libraries will be prepared and transfered to the relevant partners. Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2016 |
Demonstrators, pilots, prototypes | 2020-03-23 |
Libraries of enzyme mutants preparedGenerate knowledge-based focussed enzyme mutant libraries Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2016 |
Documents, reports | 2020-03-23 |
Cofactor-independent oxygenases with few new functions identified within the tautomerase superfamilyIdentification and functional characterisation of new cofactor-independent oxygenases within the tautomerase superfamily, with special focus on hypothetical oxygenases for which the genomic context gives clues about their physiological function. Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2016 |
Documents, reports | 2020-03-23 |
Identification of substrates and inhibitors of HPP oxygenaseIn-depth mechanistic and structural studies of a cofactor-independent monooxygenase from the tautomerase superfamily that catalyses the oxidative cleavage of HPP. Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2016 |
Documents, reports | 2020-03-23 |
PQS-cleaving cofactor-independent dioxygenases purified and functionally characterisedIsolation of new cofactor-independent dioxygenases from the alpha/beta hydrolase fold superfamily active toward the Pseudomonas quinolone signal (PQS), exploiting natural genetic diversity; and functional characterisation of PQS-cleaving enzymes, with a focus on substrate specificity and affinity, catalytic efficiency, and applicability to interfere with quorum sensing. Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2016 |
Documents, reports | 2020-03-23 |
Libraries of LPMO mutants preparedMutants of LPMOs will be prepared and checked for activity. Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2016 |
Demonstrators, pilots, prototypes | 2020-03-23 |
Identification of amino acid positions that govern selectivity of three heme-dependent monooxygenasesInvestigation of three heme-dependent monooxygenases for the conversion of heterocyclic compounds. Through modelling and random mutagenesis positions will be identified and mutated to elucidate on the molecular level structure-function relationships. Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2016 |
Documents, reports | 2020-03-23 |
Flavin-dependent monooxygenases produced and purifiedThe work will focus on eukaryotic flavin-containing monooxygenases that are essential for the detoxification of xenobiotics. The target enzymes will be produced and purified using protein chromatography. Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2016 |
Documents, reports | 2020-03-23 |
OXYTRAIN vacancies advertisedFor identifying ESR candidates, OXYTRAIN vacancies advertised. Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2016 |
Other | 2020-03-23 |
Project WebsiteAn OXYTRAIN website will be built and launched Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2016 |
Websites, patent fillings, videos etc. | 2020-03-23 |