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METACELL-TM SIGNED

METAbolism analysis made easy for CELL Translational Medicine

Total Cost €

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EC-Contrib. €

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Partnership

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Project "METACELL-TM" data sheet

The following table provides information about the project.

Coordinator
LUXCEL BIOSCIENCES LTD 

Organization address
address: BIOTRANSFER UNIT SUITE 3-32 BIOL
city: Cork
postcode: T12
website: www.luxcel.com

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Ireland [IE]
 Project website https://www.agilent.com/en/metacell
 Total cost 3˙313˙827 €
 EC max contribution 2˙459˙616 € (74%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2. (PRIORITY 'Industrial leadership')
 Code Call H2020-FTIPilot-2016-1
 Funding Scheme IA
 Starting year 2016
 Duration (year-month-day) from 2016-11-01   to  2019-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    LUXCEL BIOSCIENCES LTD IE (Cork) coordinator 695˙481.00
2    NCARDIA AG DE (KOLN) participant 556˙437.00
3    BMG LABTECH GMBH DE (ORTENBERG) participant 492˙081.00
4    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD UK (OXFORD) participant 249˙268.00
5    AGILENT TECHNOLOGIES IRELAND LIMITED IE (DUBLIN) participant 240˙159.00
6    IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE UK (LONDON) participant 226˙187.00

Map

 Project objective

'The healthcare industry is experiencing unprecedented rates of drug failure, long development times and high costs - because current lab tests and disease models (in vitro) don’t adequately predict drug effect in the patient (in vivo).

To address this “Challenge”, three leading EU SMEs; Luxcel Biosciences Ltd, Axiogenesis AG and BMG Labtech GmbH, are partnering to bring to market, a fully integrated targeted metabolomics Test Platform, comprising physiologically relevant in vitro cell assays and easy to use test kits, configured for use with the multimode fluorescence plate reader; instrumentation, which is installed in, or else is easily accessible to every cell biology lab globally.

The innovation “Solution' is made possible by Luxcel’s unique and patented optical nanosensor technology, and its integration to create entirely new ‘functionally-connected’ in vitro tests. The scope of the project is to finalize development of the cell-based assay platform towards market introduction, productise, pilot and demonstrate it with key opinion leaders; for modular product launch through the project and full launch early 2019.

Leveraging existing global sales channels, the three industrial partners are targeting revenues of EUR 15 million by 2023. In total, about 24-29 new jobs will be created by 2023; with 6 new jobs during the project. All three SMEs are passionate about the MetaCell-TM solution, and expect that a successful outcome will see them positioned as No. 1 in their respective fields in Europe and internationally. '

 Deliverables

List of deliverables.
Sales Account Manager Recruitment Other 2020-01-30 18:37:58
Hosted ‘WEB-PORTAL’, developed and launched Other 2020-01-30 18:37:58

Take a look to the deliverables list in detail:  detailed list of METACELL-TM deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 M. Schwalfenberg, R. McGarrigle, C. Carey and J. Hynes
Multiplexed Screening of Drug-Induced MitochondrialDysfunction and Cytotoxicity
published pages: , ISSN: , DOI:
2020-01-30
2018 C. Wark, C. Carey, R. Kettenhofen, M. Schwalfenberg, J. Hynes
The CLARIOstar® with ACU exposes cells to ischemiareperfusion conditions and monitors their oxygenation
published pages: , ISSN: , DOI:
2020-01-30
2017 M. Potter, J. Hynes, A. Nijhuis, C. Carey, I. Hayes, C. Zois, A. Harris, H. Keun, K. Morten
The importance of cellular oxygenation measurements in the analysis of hypoxia-induced signalling and related metabolic adaptation
published pages: , ISSN: , DOI:
2020-01-30
2017 C. Carey, R. Kettenhofen, M. Schneider, J. Hynes
Microplate-based ischemia-reperfusion model with real-time monitoring of cellular oxygenation and reactive oxygen species generation
published pages: , ISSN: , DOI:
2020-01-30
2017 C. Carey, C. Bertinetti-Lapatki, R. Kettenhofen, A. Roth, J Hynes.
Investigating Drug Induced Cardiomyocyte Dysfunction through Combined Analysis of Beating, Metabolic Flux and Cellular Oxygenation
published pages: , ISSN: , DOI:
2020-01-30
2017 C. Carey, R. Kettenhofen, M. Schneider, M. Schwalfenberg, J. Hynes
High-throughput in vitro ischemia-reperfusion model with real-time monitoring of cellular oxygenation and reactive oxygen species generation
published pages: , ISSN: , DOI:
2020-01-30
2017 M. Schwalfenberg, R. McGarrigle, C. Carey, J. Hynes
Modelling tumour hypoxia through parallel analysis of cellular oxygenation, glycolytic flux and mitochondrial function
published pages: , ISSN: , DOI:
2020-01-30
2017 C. Carey, T. Xinru, Y. Will, J. Hynes
A functional high-throughput screen for drug-induced modulation of fatty acid oxidation
published pages: , ISSN: , DOI:
2020-01-30
2016 D.L. Hoffman, C.A. Peters , J. Hynes
The Measurement of Cellular Bioenergetics at Defined Steady-State Oxygen Concentrations: A Novel Microplate Based Method
published pages: , ISSN: , DOI:
2020-01-30

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The information about "METACELL-TM" are provided by the European Opendata Portal: CORDIS opendata.

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