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METACELL-TM SIGNED

METAbolism analysis made easy for CELL Translational Medicine

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

METACELL-TM project word cloud

Explore the words cloud of the METACELL-TM project. It provides you a very rough idea of what is the project "METACELL-TM" about.

respective ltd metacell bmg 15 plate solution 2023 modular labtech integration patient adequately 29 assays outcome configured successful finalize leaders times positioned see accessible industry opinion optical internationally connected lab tm unprecedented functionally globally launch productise multimode 2019 tests pilot nanosensor metabolomics predict introduction patented models drug easily vivo comprising disease revenues industrial kits scope rates jobs healthcare channels vitro installed create entirely market ag instrumentation innovation million partnering sales biology global else leveraging experiencing passionate biosciences axiogenesis smes don eur platform luxcel created full fluorescence assay physiologically effect total cell made 24 reader

Project "METACELL-TM" data sheet

The following table provides information about the project.

Coordinator	LUXCEL BIOSCIENCES LTD Organization address address: BIOTRANSFER UNIT SUITE 3-32 BIOL city: Cork postcode: T12 website: www.luxcel.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Ireland [IE]
Project website	https://www.agilent.com/en/metacell
Total cost	3˙313˙827 €
EC max contribution	2˙459˙616 € (74%)
Programme	1. H2020-EU.3. (PRIORITY 'Societal challenges) 2. H2020-EU.2. (PRIORITY 'Industrial leadership')
Code Call	H2020-FTIPilot-2016-1
Funding Scheme	IA
Starting year	2016
Duration (year-month-day)	from 2016-11-01 to 2019-04-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	LUXCEL BIOSCIENCES LTD LUXCEL BIOSCIENCES LTD Organization address address: BIOTRANSFER UNIT SUITE 3-32 BIOL city: Cork postcode: T12 website: www.luxcel.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (Cork)	coordinator	695˙481.00
2	NCARDIA AG NCARDIA AG Organization address address: NATTERMANNALLEE 1 city: KOLN postcode: 50829 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (KOLN)	participant	556˙437.00
3	BMG LABTECH GMBH BMG LABTECH GMBH Organization address address: ALLMENDGRUN 8 city: ORTENBERG postcode: 77799 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (ORTENBERG)	participant	492˙081.00
4	THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD Organization address address: WELLINGTON SQUARE UNIVERSITY OFFICES city: OXFORD postcode: OX1 2JD website: www.ox.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (OXFORD)	participant	249˙268.00
5	AGILENT TECHNOLOGIES IRELAND LIMITED AGILENT TECHNOLOGIES IRELAND LIMITED Organization address address: 70 SIR JOHN ROGERSONS QUAY city: DUBLIN postcode: 2 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (DUBLIN)	participant	240˙159.00
6	IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE Organization address address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD city: LONDON postcode: SW7 2AZ website: http://www.imperial.ac.uk/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	226˙187.00

Map

Project objective

'The healthcare industry is experiencing unprecedented rates of drug failure, long development times and high costs - because current lab tests and disease models (in vitro) don’t adequately predict drug effect in the patient (in vivo).

To address this “Challenge”, three leading EU SMEs; Luxcel Biosciences Ltd, Axiogenesis AG and BMG Labtech GmbH, are partnering to bring to market, a fully integrated targeted metabolomics Test Platform, comprising physiologically relevant in vitro cell assays and easy to use test kits, configured for use with the multimode fluorescence plate reader; instrumentation, which is installed in, or else is easily accessible to every cell biology lab globally.

The innovation “Solution' is made possible by Luxcel’s unique and patented optical nanosensor technology, and its integration to create entirely new ‘functionally-connected’ in vitro tests. The scope of the project is to finalize development of the cell-based assay platform towards market introduction, productise, pilot and demonstrate it with key opinion leaders; for modular product launch through the project and full launch early 2019.

Leveraging existing global sales channels, the three industrial partners are targeting revenues of EUR 15 million by 2023. In total, about 24-29 new jobs will be created by 2023; with 6 new jobs during the project. All three SMEs are passionate about the MetaCell-TM solution, and expect that a successful outcome will see them positioned as No. 1 in their respective fields in Europe and internationally. '

Deliverables

List of deliverables.
Sales Account Manager Recruitment	Other	2020-01-30 18:37:58
Hosted â€˜WEB-PORTALâ€™, developed and launched	Other	2020-01-30 18:37:58

Take a look to the deliverables list in detail: detailed list of METACELL-TM deliverables.

Publications

List of publications.
year	authors and title	last update
2019	M. Schwalfenberg, R. McGarrigle, C. Carey and J. Hynes Multiplexed Screening of Drug-Induced MitochondrialDysfunction and Cytotoxicity published pages: , ISSN: , DOI:	2020-01-30
2018	C. Wark, C. Carey, R. Kettenhofen, M. Schwalfenberg, J. Hynes The CLARIOstarÂ® with ACU exposes cells to ischemiareperfusion conditions and monitors their oxygenation published pages: , ISSN: , DOI:	2020-01-30
2017	M. Potter, J. Hynes, A. Nijhuis, C. Carey, I. Hayes, C. Zois, A. Harris, H. Keun, K. Morten The importance of cellular oxygenation measurements in the analysis of hypoxia-induced signalling and related metabolic adaptation published pages: , ISSN: , DOI:	2020-01-30
2017	C. Carey, R. Kettenhofen, M. Schneider, J. Hynes Microplate-based ischemia-reperfusion model with real-time monitoring of cellular oxygenation and reactive oxygen species generation published pages: , ISSN: , DOI:	2020-01-30
2017	C. Carey, C. Bertinetti-Lapatki, R. Kettenhofen, A. Roth, J Hynes. Investigating Drug Induced Cardiomyocyte Dysfunction through Combined Analysis of Beating, Metabolic Flux and Cellular Oxygenation published pages: , ISSN: , DOI:	2020-01-30
2017	C. Carey, R. Kettenhofen, M. Schneider, M. Schwalfenberg, J. Hynes High-throughput in vitro ischemia-reperfusion model with real-time monitoring of cellular oxygenation and reactive oxygen species generation published pages: , ISSN: , DOI:	2020-01-30
2017	M. Schwalfenberg, R. McGarrigle, C. Carey, J. Hynes Modelling tumour hypoxia through parallel analysis of cellular oxygenation, glycolytic flux and mitochondrial function published pages: , ISSN: , DOI:	2020-01-30
2017	C. Carey, T. Xinru, Y. Will, J. Hynes A functional high-throughput screen for drug-induced modulation of fatty acid oxidation published pages: , ISSN: , DOI:	2020-01-30
2016	D.L. Hoffman, C.A. Peters , J. Hynes The Measurement of Cellular Bioenergetics at Defined Steady-State Oxygen Concentrations: A Novel Microplate Based Method published pages: , ISSN: , DOI:	2020-01-30

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The information about "METACELL-TM" are provided by the European Opendata Portal: CORDIS opendata.