Opendata, web and dolomites

Learn2Walk SIGNED

Brain meets spine: the neural origin of toddler’s first steps

Total Cost €


EC-Contrib. €






 Learn2Walk project word cloud

Explore the words cloud of the Learn2Walk project. It provides you a very rough idea of what is the project "Learn2Walk" about.

ones    gradual    latter    patterns    fundamental    elucidate    answer    emergent    small    spontaneously    2011    toddlers    muscle    opportunity    neural    identification    demonstrated    independently    circuitry    stepping    pioneering    science    instinct    overarching    retained    impairment    neuro    locomotor    takes    published    leap    provides    insights    plan    perform    cortical    character    onset    interaction    first    spontaneous    techniques    supplemented    rehabilitation    unraveling    cerebral    activation    basic    brain    learning    interplay    altered    reorganization    walk    cortico    start    motor    impairments    normal    one    manifest    moment    profound    ambition    seminal    indicative    optimal    neonate    strategy    property    coordinated    realize    giant    child    triggered    reflex    born    hardwired    walking    independent    emergence    underlying    children    combined    questions    muscular    accompanying    me    palsy    changing   

Project "Learn2Walk" data sheet

The following table provides information about the project.


Organization address
address: DE BOELELAAN 1105
postcode: 1081 HV

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 1˙331˙625 €
 EC max contribution 1˙331˙625 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2016-STG
 Funding Scheme ERC-STG
 Starting year 2017
 Duration (year-month-day) from 2017-02-01   to  2022-01-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    STICHTING VU NL (AMSTERDAM) coordinator 1˙331˙625.00


 Project objective

A child’s first steps may be small, but they are a giant leap for its development. Children have an instinct to walk from the moment they are born – a 'stepping reflex' hardwired in their neural circuitry – but it typically takes about one year before they can start walking independently. In a pioneering work published on Science in 2011, I demonstrated that the coordinated muscle activation in neonate stepping is described by two basic activation patterns that are retained throughout development, and supplemented by two new ones that be-come manifest in toddlers. These seminal findings triggered profound questions: Is the development of new patterns an emergent property, indicative of spontaneously changing cortico-muscular interaction? Does locomotor impairment change the spontaneous character of this emergent property into a gradual one? With the proposed research, I plan to answer these questions by studying the interplay between brain and muscular activity at the onset of independent walking. The overarching aim is to characterize the emergence of independent walking in typically developing children and in children affected by cerebral palsy, and to identify an optimal rehabilitation strategy to promote normal walking in the latter. I plan to perform a combined analysis of brain and muscular activity in typically developing children, unraveling the detailed processes underlying the learning of walking. I will then elucidate the reorganization of cortical and cortico-muscular activity accompanying the altered development of walking in children with cerebral palsy. Finally, I will apply these results to the identification of optimal rehabilitation techniques for children with cerebral palsy. It is my long-term ambition to exploit fundamental insights into neuro-motor control for promoting normal walking in children with locomotor impairments. The proposed project provides an exciting opportunity for me to realize this goal.


year authors and title journal last update
List of publications.
2019 Adam T. C. Booth, Marjolein M. van der Krogt, Jaap Harlaar, Nadia Dominici, Annemieke I. Buizer
Muscle Synergies in Response to Biofeedback-Driven Gait Adaptations in Children With Cerebral Palsy
published pages: , ISSN: 1664-042X, DOI: 10.3389/fphys.2019.01208
Frontiers in Physiology 10 2019-11-13
2019 A. Bekius, C.S. Zandvoort, J.N. Kerkman, A. Daffertshofer, J. Harlaar A.I. Buizer, and N. Dominici
Poster Presentations
published pages: 62-82, ISSN: 0012-1622, DOI: 10.1111/dmcn.14245
Developmental Medicine & Child Neurology 61/S2 2019-09-20
2018 Bekius A, Kerkman JN, Zandvoort CS, Daffertshofer A, Buizer AI, Halaar J, Dominici N.
Oral Presentations
published pages: 4-27, ISSN: 0012-1622, DOI: 10.1111/dmcn.13789
Developmental Medicine & Child Neurology 60 2019-09-20
2019 Coen S. Zandvoort, Jaap H. van Dieën, Nadia Dominici, Andreas Daffertshofer
The human sensorimotor cortex fosters muscle synergies through cortico-synergy coherence
published pages: 30-37, ISSN: 1053-8119, DOI: 10.1016/j.neuroimage.2019.05.041
NeuroImage 199 2019-08-29

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "LEARN2WALK" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email ( and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "LEARN2WALK" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)


The Mass Politics of Disintegration

Read More  

InsideChromatin (2019)

Towards Realistic Modelling of Nucleosome Organization Inside Functional Chromatin Domains

Read More  

TOROS (2019)

A Theory-Oriented Real-Time Operating System for Temporally Sound Cyber-Physical Systems

Read More