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Bronchomycn

First in class epithelial Barrier-enhancing medicine for respiratory diseases

Total Cost €

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EC-Contrib. €

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Partnership

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 Outcomes and results

 Bronchomycn project word cloud

Explore the words cloud of the Bronchomycn project. It provides you a very rough idea of what is the project "Bronchomycn" about.

continue    membrane    caused    2021    regulatory    2018    64    disease    drug    epithelium    plan    airway    compounds    27    forecast    toxins    24    complications    investment    2014    23    807    antibiotic    additional    sales    agents    2015    world    give    29    commercialization    mill    decreasing    points    ebf    considering    2022    14    save    organization    morbidity    valued    deaths    epiendo    belong    commercializing    cell    near    bronchomycn    rodents    usa    economic    28    azithromycin    decided    barriolides    drugs    respiratory    accounted    market    respectively    barrier    stages    2024    stem    people    pulmonary    class    obstructive    ipr    treatment    2026    lacks    permeability    disorder    start    clinical    structurally    billion    200    12    2004    suffered    invested    efficient    acts    therapeutics    chronic    million    2    protection    infectious    copd    health    vivo    speed    48    roi    burden    preclinical    turnover    consequence    49    hospital    university    ready    epithelial    prepare    medical   

Project "Bronchomycn" data sheet

The following table provides information about the project.

Coordinator		 EPI-ENDO PHARMACEUTICALS EHF 

Organization address
address: 28 BORGARTUNI
city: REYKJAVIK
postcode: 105
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country Iceland [IS]
 Project website http://www.epiendo.com
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2017
 Duration (year-month-day) from 2017-02-01   to  2017-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EPI-ENDO PHARMACEUTICALS EHF IS (REYKJAVIK) coordinator 50˙000.00

Map

 Project objective

Chronic obstructive pulmonary disease (COPD) is a respiratory disorder that presents airway epithelial barrier failure (EBF) for which there are no efficient drugs, being a leading cause of chronic morbidity.

According to the World Health Organization 64 million people suffered COPD in 2004. The EU-28 and USA accounted for 23 and 12.7 million people respectively, which caused near 200,000 deaths. As a consequence of the medical complications of COPD the economic burden has been estimated as € 48.4 and € 29.3 billion in EU-28 and USA respectively

EpiEndo, aims at commercializing a new drug which will be able to save € 27 billion to EU-28 and USA.

Bronchomycn belong to Barriolides, a new class of compounds that provide effective treatment against EBF. Bronchomycn is structurally based on the well-known azithromycin, but lacks antibiotic activity and it acts by decreasing the permeability of the pulmonary epithelium membrane to toxins and infectious agents.

We have been working since 2014 in collaboration with the Stem Cell Research Unit and the University Hospital and now our product is in the early in-vivo stages, for what we have invested € 0.5 Mill. In order to get Bronchomycn to the market, we will start the Clinical studies in 2018 and we expect that current knowledge about side effects of azithromycin speed up the process so that the product will be ready for commercialization in 2021.

During Phase 1 we will prepare the preclinical studies in rodents and clinical studies and defining end-points and regulatory requirements, prepare IPR protection plan, etc.

The market for Bronchomycn is the respiratory therapeutics market which was valued at € 24.8 billion in 2015. We plan to start our sales in Europe in 2022 and USA in 2024, so that by 2026 our turnover will reach €807 Mill.

Therefore, we have decided to continue with Bronchomycn for what we need an additional investment of € 49 Mill, that considering a 5-years forecast will give us a ROI of 14.2

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "BRONCHOMYCN" project.

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The information about "BRONCHOMYCN" are provided by the European Opendata Portal: CORDIS opendata.

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