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Bronchomycn

First in class epithelial Barrier-enhancing medicine for respiratory diseases

Total Cost €

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EC-Contrib. €

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Partnership

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 Bronchomycn project word cloud

Explore the words cloud of the Bronchomycn project. It provides you a very rough idea of what is the project "Bronchomycn" about.

2022    market    200    start    continue    turnover    drug    epiendo    27    belong    deaths    considering       stages    consequence    807    barriolides    clinical    2014    preclinical    burden    class    2024    suffered    ebf    regulatory    lacks    treatment    12    antibiotic    therapeutics    64    permeability    invested    complications    medical    sales    48    prepare    accounted    mill    29    obstructive    drugs    save    commercializing    compounds    disease    health    respectively    ready    23    protection    decided    commercialization    give    decreasing    near    plan    azithromycin    pulmonary    2015    bronchomycn    organization    2004    hospital    university    morbidity    rodents    stem    roi    chronic    cell    infectious    forecast    caused    people    2018    investment    2026    points    airway    28    epithelium    agents    ipr    respiratory    additional    structurally    2021    acts    efficient    copd    disorder    epithelial    usa    speed    economic    world    14    49    vivo    24    toxins    billion    barrier    membrane    valued    million   

Project "Bronchomycn" data sheet

The following table provides information about the project.

Coordinator
EPI-ENDO PHARMACEUTICALS EHF 

Organization address
address: 28 BORGARTUNI
city: REYKJAVIK
postcode: 105
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Iceland [IS]
 Project website http://www.epiendo.com
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2017
 Duration (year-month-day) from 2017-02-01   to  2017-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EPI-ENDO PHARMACEUTICALS EHF IS (REYKJAVIK) coordinator 50˙000.00

Map

 Project objective

Chronic obstructive pulmonary disease (COPD) is a respiratory disorder that presents airway epithelial barrier failure (EBF) for which there are no efficient drugs, being a leading cause of chronic morbidity.

According to the World Health Organization 64 million people suffered COPD in 2004. The EU-28 and USA accounted for 23 and 12.7 million people respectively, which caused near 200,000 deaths. As a consequence of the medical complications of COPD the economic burden has been estimated as € 48.4 and € 29.3 billion in EU-28 and USA respectively

EpiEndo, aims at commercializing a new drug which will be able to save € 27 billion to EU-28 and USA.

Bronchomycn belong to Barriolides, a new class of compounds that provide effective treatment against EBF. Bronchomycn is structurally based on the well-known azithromycin, but lacks antibiotic activity and it acts by decreasing the permeability of the pulmonary epithelium membrane to toxins and infectious agents.

We have been working since 2014 in collaboration with the Stem Cell Research Unit and the University Hospital and now our product is in the early in-vivo stages, for what we have invested € 0.5 Mill. In order to get Bronchomycn to the market, we will start the Clinical studies in 2018 and we expect that current knowledge about side effects of azithromycin speed up the process so that the product will be ready for commercialization in 2021.

During Phase 1 we will prepare the preclinical studies in rodents and clinical studies and defining end-points and regulatory requirements, prepare IPR protection plan, etc.

The market for Bronchomycn is the respiratory therapeutics market which was valued at € 24.8 billion in 2015. We plan to start our sales in Europe in 2022 and USA in 2024, so that by 2026 our turnover will reach €807 Mill.

Therefore, we have decided to continue with Bronchomycn for what we need an additional investment of € 49 Mill, that considering a 5-years forecast will give us a ROI of 14.2

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "BRONCHOMYCN" project.

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The information about "BRONCHOMYCN" are provided by the European Opendata Portal: CORDIS opendata.

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