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Nod2Root SIGNED

Keeping nodules in check: Interplay of rhizobial and host factors controlling nodule morphogenesis and identity in legume plants.

Total Cost €

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EC-Contrib. €

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Partnership

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 Nod2Root project word cloud

Explore the words cloud of the Nod2Root project. It provides you a very rough idea of what is the project "Nod2Root" about.

ongoing    cells    specialized    legumes    nbcl    sativum    sigma    genetics    integrity    symbiotic    ectopic    gene    identity    root    legume    wp2    mutants    maintained    mechanisms    unravel    bop    combine    lacking    elicited    regulation    determinate    organs    hosts    light    deep    checkpoint    plants    nodule    fusions    fixation    rhizobia    combination    morphogenetic    roots    decipher    biology    model    origin    recognition    rhizobial    organogenesis    insights    ecfg    formed    noot    determinants    stress    mutant    truncatula    bacteria    bradyrhizobium    soybean    conversion    altogether    plant    takes    pisum    interestingly    diazoefficiens    metabolic    metabolites    medicago    molecular    transcriptomics    metabolomics    nodules    persistence    wp1    tip    orthologs    attempts    repressing    pointing    place    genes    coch    underlying    economically    group    nodulation    unravelled    host    reporter    networks    nitrogen    engineer    cellular    former    signalling    cell    delta    wp3    found   

Project "Nod2Root" data sheet

The following table provides information about the project.

Coordinator
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH 

Organization address
address: Raemistrasse 101
city: ZUERICH
postcode: 8092
website: https://www.ethz.ch/de.html

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Project website http://www.micro.biol.ethz.ch/research/vorholt/fischer.html
 Total cost 187˙419 €
 EC max contribution 187˙419 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2017
 Duration (year-month-day) from 2017-03-01   to  2019-02-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) coordinator 187˙419.00

Map

 Project objective

Symbiotic nitrogen fixation by rhizobia takes place in specialized organs of legume host plants, the root nodules. While rather deep molecular insights into plant-rhizobia recognition, early nodule organogenesis, regulation of nodulation and nitrogen fixation are available, much less is known about how nodule integrity is maintained and the origin of the underlying morphogenetic program. Recently, NOOT BOP COCH LIKE (NBCL) genes of Medicago truncatula and Pisum sativum were found to ensure nodule integrity by repressing ectopic root formation (applicant's former project). Interestingly, soybean nodules elicited by a Bradyrhizobium diazoefficiens mutant lacking the general stress response sigma factor σEcfG also formed ectopic roots (host's project), pointing to a bacteria-plant signalling system that is crucial for nodule persistence and integrity. Here, we propose to decipher the molecular determinants that maintain determinate nodule identity using the B. diazoefficiens – soybean model. We will combine plant molecular genetics, cell biology with transcriptomics and metabolomics to unravel cells, genes and metabolic networks that contribute to the checkpoint system ensuring nodule integrity. In work package 1 (WP1), the role of three soybean NBCL orthologs will be unravelled. In WP2, the nodule-to-root conversion characteristic for B. diazoefficiens ΔecfG mutants will be studied at the cellular level using root tip-specific reporter fusions. In WP3, a combination of metabolomics and transcriptomics will be applied to identify metabolites and gene networks involved in the nodule-to-root conversion elicited by ΔecfG and nbcl mutants. Altogether, results of this project will provide insight into determinants and mechanisms used by the economically important group of soybean plants to maintain the integrity of specialized, root-derived organs, an aspect that is relevant also in the light of ongoing attempts to engineer non-legumes into rhizobial hosts.

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The information about "NOD2ROOT" are provided by the European Opendata Portal: CORDIS opendata.

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