Explore the words cloud of the Nod2Root project. It provides you a very rough idea of what is the project "Nod2Root" about.
The following table provides information about the project.
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
|Coordinator Country||Switzerland [CH]|
|Total cost||187˙419 €|
|EC max contribution||187˙419 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2017-03-01 to 2019-02-28|
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|1||EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH||CH (ZUERICH)||coordinator||187˙419.00|
Symbiotic nitrogen fixation by rhizobia takes place in specialized organs of legume host plants, the root nodules. While rather deep molecular insights into plant-rhizobia recognition, early nodule organogenesis, regulation of nodulation and nitrogen fixation are available, much less is known about how nodule integrity is maintained and the origin of the underlying morphogenetic program. Recently, NOOT BOP COCH LIKE (NBCL) genes of Medicago truncatula and Pisum sativum were found to ensure nodule integrity by repressing ectopic root formation (applicant's former project). Interestingly, soybean nodules elicited by a Bradyrhizobium diazoefficiens mutant lacking the general stress response sigma factor σEcfG also formed ectopic roots (host's project), pointing to a bacteria-plant signalling system that is crucial for nodule persistence and integrity. Here, we propose to decipher the molecular determinants that maintain determinate nodule identity using the B. diazoefficiens – soybean model. We will combine plant molecular genetics, cell biology with transcriptomics and metabolomics to unravel cells, genes and metabolic networks that contribute to the checkpoint system ensuring nodule integrity. In work package 1 (WP1), the role of three soybean NBCL orthologs will be unravelled. In WP2, the nodule-to-root conversion characteristic for B. diazoefficiens ΔecfG mutants will be studied at the cellular level using root tip-specific reporter fusions. In WP3, a combination of metabolomics and transcriptomics will be applied to identify metabolites and gene networks involved in the nodule-to-root conversion elicited by ΔecfG and nbcl mutants. Altogether, results of this project will provide insight into determinants and mechanisms used by the economically important group of soybean plants to maintain the integrity of specialized, root-derived organs, an aspect that is relevant also in the light of ongoing attempts to engineer non-legumes into rhizobial hosts.
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The information about "NOD2ROOT" are provided by the European Opendata Portal: CORDIS opendata.