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Keeping nodules in check: Interplay of rhizobial and host factors controlling nodule morphogenesis and identity in legume plants.

Total Cost €


EC-Contrib. €






 Nod2Root project word cloud

Explore the words cloud of the Nod2Root project. It provides you a very rough idea of what is the project "Nod2Root" about.

recognition    hosts    regulation    morphogenetic    nodules    sativum    transcriptomics    organogenesis    light    stress    underlying    elicited    biology    legume    bop    coch    mutant    medicago    networks    fusions    determinate    delta    insights    nodule    root    genetics    conversion    persistence    metabolites    plant    reporter    model    plants    tip    unravelled    rhizobia    group    engineer    nodulation    rhizobial    cells    nbcl    gene    determinants    bradyrhizobium    soybean    pointing    molecular    unravel    combine    mechanisms    diazoefficiens    economically    genes    ectopic    wp2    metabolic    takes    checkpoint    orthologs    signalling    attempts    legumes    mutants    roots    formed    identity    origin    found    ecfg    organs    former    pisum    lacking    symbiotic    altogether    nitrogen    sigma    integrity    cell    maintained    combination    bacteria    host    noot    fixation    cellular    wp1    place    truncatula    repressing    wp3    metabolomics    deep    decipher    specialized    interestingly    ongoing   

Project "Nod2Root" data sheet

The following table provides information about the project.


Organization address
address: Raemistrasse 101
postcode: 8092

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Project website
 Total cost 187˙419 €
 EC max contribution 187˙419 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2017
 Duration (year-month-day) from 2017-03-01   to  2019-02-28


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

Symbiotic nitrogen fixation by rhizobia takes place in specialized organs of legume host plants, the root nodules. While rather deep molecular insights into plant-rhizobia recognition, early nodule organogenesis, regulation of nodulation and nitrogen fixation are available, much less is known about how nodule integrity is maintained and the origin of the underlying morphogenetic program. Recently, NOOT BOP COCH LIKE (NBCL) genes of Medicago truncatula and Pisum sativum were found to ensure nodule integrity by repressing ectopic root formation (applicant's former project). Interestingly, soybean nodules elicited by a Bradyrhizobium diazoefficiens mutant lacking the general stress response sigma factor σEcfG also formed ectopic roots (host's project), pointing to a bacteria-plant signalling system that is crucial for nodule persistence and integrity. Here, we propose to decipher the molecular determinants that maintain determinate nodule identity using the B. diazoefficiens – soybean model. We will combine plant molecular genetics, cell biology with transcriptomics and metabolomics to unravel cells, genes and metabolic networks that contribute to the checkpoint system ensuring nodule integrity. In work package 1 (WP1), the role of three soybean NBCL orthologs will be unravelled. In WP2, the nodule-to-root conversion characteristic for B. diazoefficiens ΔecfG mutants will be studied at the cellular level using root tip-specific reporter fusions. In WP3, a combination of metabolomics and transcriptomics will be applied to identify metabolites and gene networks involved in the nodule-to-root conversion elicited by ΔecfG and nbcl mutants. Altogether, results of this project will provide insight into determinants and mechanisms used by the economically important group of soybean plants to maintain the integrity of specialized, root-derived organs, an aspect that is relevant also in the light of ongoing attempts to engineer non-legumes into rhizobial hosts.

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The information about "NOD2ROOT" are provided by the European Opendata Portal: CORDIS opendata.

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