Opendata, web and dolomites
H2020 projects about "mutant"
The page lists 124 projects related to the topic "mutant".
| # | |||
|---|---|---|---|
| 1 | BRIDGES | Breast Cancer Risk after Diagnostic Gene Sequencing (BRIDGES) | 2015 |
| 2 | MoTriColor | Molecularly guided trials with specific treatment strategies in patients with advanced newly molecular defined subtypes of colorectal cancer (MoTriColor) | 2015 |
| 3 | INTRAHETEROSEQ | Molecular characterization of the role of intra-tumor heterogeneity in cancer progression and metastasis | 2015 |
| 4 | AngioGenesHD | Epistasis analysis of angiogenes with high cellular definition | 2015 |
| 5 | REDSTEM | Development of a new plant variety for the Asian market | 2015 |
| 6 | Fingers4Cure | Zinc finger gene therapy in the brain for treating Huntington's disease | 2015 |
| 7 | LYMPHORG | Organ-specific mechanisms of lymphatic vascular development and specialisation | 2015 |
| 8 | Clock Mechanics | Mechanosensation and the circadian clock: a reciprocal analysis | 2015 |
| 9 | FeSensor | Finding the iron sensing protein in crop plants | 2015 |
| 10 | RncRNAA | Functions of non-coding RNAs in protein synthesis and homeostasis during aging | 2015 |
| 11 | GUTWORM | Unravelling host intestine-parasite interactions that define immune responses to whipworms | 2015 |
| 12 | RESILIENCE | RESILIENT2: A novel thermosensory module at the interface of temperature and defense signaling | 2015 |
| 13 | miRTurnOver | Identifying genes involved in microRNA turnover in Arabidopsis | 2015 |
| 14 | AND | Antibacterial (Nano)medicines Development | 2015 |
| 15 | SSPinROOTS | Small Signalling Peptides for Stimulating Root Growth - a Novel Approach to Improve Nutrient Use Efficiency | 2015 |
| 16 | ParaplegiaERDros | Roles of spastic paraplegia proteins in organisation of axonal endoplasmic reticulum | 2016 |
| 17 | INFANT MICROBIOTA | Elucidating how Bifidobacteria shapes the microbiota in response to infant diet. | 2015 |
| 18 | SENSITIVITYMARKERS | Clinical validation of prognostic biomarkers of chemotherapy response in liquid biopsies | 2015 |
| 19 | Dementia | DNA rEpair impaired Mice with accElerated Neurodegeneration as Tool to Improve Alzheimer therapeutics | 2015 |
| 20 | GliaInnateSensing | Glia-derived factors in innate lymphoid cell sensing and intestinal defence | 2015 |
| 21 | PhageDiff | Distinct Infection Dynamics and Ecological Success among Closely Related Marine Cyanophages: Why the Differences? | 2015 |
| 22 | COMAL | COMAL:COhesin Mutations in Acute Leukemia: from modeling and mechanisms to novel therapeutics | 2015 |
| 23 | PLICO | Plant lipidome remodelling during cold acclimation | 2016 |
| 24 | TARG-SUP | Targeting TGF-β activation, likely the core mechanism of immunosuppression by human regulatory T cells. | 2016 |
| 25 | MCNTMTDC | Metabolic control on NF-κB activity during dendritic cells-mediated immune tolerance to tumours | 2017 |
| 26 | INTEGRISTEM | Functions of Integrins in Mammary Stem Cell Activity and Tumorigenesis | 2016 |
| 27 | RESTRIVIR | Characterization of a novel mechanism restricting virus infection in reproductive tissues | 2016 |
| 28 | XPGCS | Single cell profiling of X chromosome reactivation during primordial germ cell specification in vivo | 2016 |
| 29 | JHSIGNAL | Modulation of juvenile hormone signaling by receptor phosphorylation | 2017 |
| 30 | CYgnaling | Probing the role of orphan Cytochrome P450 oxygenases in signaling compounds biosynthesis in plants by a comparative genomics and gene conservation approach | 2016 |
| 31 | BoostR | Engineering disease resistance gene networks: synthetic helpers for expanded sensors | 2016 |
| 32 | GeneREFORM | Genetically Encoded Multicolor Reporter Systems For Multiplexed MRI | 2016 |
| 33 | HGTCODONUSE | The evolutionary significance of synonymous variations: Can codon usage preferences drive the propagation of antibiotic resistance? | 2016 |
| 34 | GTR | Dissecting gamma-TuRC composition and activity by Single Molecule Pull-down | 2017 |
| 35 | MITOBIOPATH | DISCOVERING NEW DISEASE PATHWAYS AFFECTING mtDNA METABOLISM | 2016 |
| 36 | 2MoveMate4Melanoma | A treatment for BRAF inhibitor resistant melanoma | 2016 |
| 37 | ZMOD | Blood Vessel Development and Homeostasis: Identification and Functional Analysis of Genetic Modifiers | 2016 |
| 38 | TransSplicHD | Single-Cell Transcriptomics and Spliceosome analysis to uncover new mechanisms of neuronal vulnerability to Huntington’s Disease. | 2016 |
| 39 | TRANSREAD | Restoration of tumor suppressor function by induction of translational read-through of premature termination codons - a strategy for improved cancer therapy | 2016 |
| 40 | BRCANCER | A novel approach for modeling development of breast cancer | 2016 |
| 41 | RTEL1inHHS | Characterization of RTEL1 mutations in Hoyeraal-Hreidarsson Syndrome | 2017 |
| 42 | THERACAN | Novel therapeutic strategies to treat pancreatic and lung cancer | 2017 |
| 43 | CD40-INN | CD40 goes innate: defining and targeting CD40 signaling intermediates in the macrophage to treat atherosclerosis | 2016 |
| 44 | ALS-Networks | Defining functional networks of genetic causes for ALS and related neurodegenerative disorders | 2017 |
| 45 | INFRAFRONTIER2020 | Towards enduring mouse resources and services advancing research into human health and disease | 2017 |
| 46 | MYCONEUTROPHILS | Elucidating the involvement of neutrophils in the pathogenesis of tuberculosis using a zebrafish model | 2017 |
| 47 | GSTHgNDD | Role of GST gene variation in susceptibility to mercury (Hg)-induced neurodevelopmental disorders (NDD) in zebrafish | 2017 |
| 48 | DSR | Dissipative Self-Replication | 2017 |
| 49 | Nod2Root | Keeping nodules in check: Interplay of rhizobial and host factors controlling nodule morphogenesis and identity in legume plants. | 2017 |
| 50 | PROFOLIG | Covalent-ligation-assisted elucidation of protein-aromatic foldamer interactions | 2017 |
| 51 | Vanrestrep | Vancomycin resistance regulation in the antibiotic-producers streptomycetes | 2018 |
| 52 | meltRBP | Tracking interactions between RNA and RNA-binding proteins by thermal profiling of the proteome | 2017 |
| 53 | BIOFERTICELLULASER | Role of bacterial cellulases in the transition from free living to root endophytes in rapeseed crops and in the design of efficient biofertilizers | 2017 |
| 54 | SupaSteD | Suppresion of adaptive immunity by the Salmonella effector SteD | 2017 |
| 55 | ExItALS | RNA-mediated intercellular miscommunication: role of extracellular vesicle cargos in Amyotrophic Lateral Sclerosis | 2017 |
| 56 | HUNTINFISH | Generation of new zebrafish models for the study of the pathogenesis of Huntington´s disease and for the identification of new therapeutic targets. | 2018 |
| 57 | ACtIVAtE | The virulence potential of human pathogens: how Acinetobacter baumannii survives Acanthamoeba castellanii predation | 2018 |
| 58 | MuSCel Genome | Muscle Specific C. elegans Genome in health and disease: finding novel factors in 3D organization | 2017 |
| 59 | INSPirAUTOR | Understanding how Inositol Polyphosphates regulate autophagy and lipid body formation in photosynthetic organisms: crosstalk with TOR signaling. | 2018 |
| 60 | TNFaLysMyr | Unique TNFα lysine myristoylation; elucidating its function, regulation and integration into inflammation | 2018 |
| 61 | AcTaferon | Revitalizing the clinical potential of type I IFNs in fighting influenza A virus infections with AcTaferon. | 2017 |
| 62 | NanoZfish | Restoration of motor dysfunction in vivo through nanomaterials based devices | 2017 |
| 63 | INIMUD | Impact of Neuromedin U in type 2 immunity and mucosal defence | 2017 |
| 64 | NUMELAT | Numbers in the brain: the impact of brain lateralization on numerical abilities | 2018 |
| 65 | UNREDE | Understanding Non-Photochemical Quenching Regulation in a Dynamic Environment. | 2018 |
| 66 | COMPCON | Competition under (niche) construction | 2017 |
| 67 | TreasureDrop | Directed Evolution of Enzyme for Applied Biocatalysis at Ultrahigh Throughput in Picoliter Droplets | 2017 |
| 68 | FASTER | Faster magic-angle spinning leads to a resolution revolution in biological solid-state NMR | 2017 |
| 69 | PlasmaCellControl | Transcriptional control of plasma cell development and function | 2018 |
| 70 | onCOMBINE | Towards evidence-based combinations of approved and novel cancer drugs | 2017 |
| 71 | noRAG-TOR | Rag-independent regulation of mTOR by Amino Acids | 2018 |
| 72 | FAITh | Fighting Anxiety with Importin-based Therapeutics | 2017 |
| 73 | Sense2SurviveSalt | Surviving salinity: How do plants sense Na+? | 2018 |
| 74 | MCDS-Therapy | Repurposing of carbamazepine for treatment of skeletal dysplasia | 2017 |
| 75 | COLOSSUS | Advancing a Precision Medicine Paradigm in metastatic Colorectal Cancer: Systems based patient stratification solutions | 2018 |
| 76 | miRCell | MicroRNA functions in single cells | 2018 |
| 77 | AltCheM | In vivo functional screens to decipher mechanisms of stochastically- and mutationally-induced chemoresistance in Acute Myeloid Leukemia | 2018 |
| 78 | MASTFAST | Rapid production of HUMAN MAST CELLS | 2017 |
| 79 | CMTaaRS | Defective protein translation as a pathogenic mechanism of peripheral neuropathy | 2018 |
| 80 | Alpha-Synuclein | Blocking the prion-like disease propagation in Parkinson’s disease and related disorders – model development and identification of cell-autonomous and cell non-autonomous factors. | 2019 |
| 81 | NEUROGUIDE | Study of neuronal sensing and migration/guidance dynamics in neurodevelopmental disorders by nano-engineered chips | 2018 |
| 82 | ChemRAS | Chemical probing of transcriptional RAS effectors | 2019 |
| 83 | EnCAge | Progeria models to study endothelial cell ageing: implications for organ regeneration and fibrosis | 2020 |
| 84 | NACHO | Nicotine actions on beta cell function in health and disease | 2018 |
| 85 | Flat_Leaf | How to grow a flat leaf? | 2019 |
| 86 | GlycoPCs | How do Pharmacological Chaperones work? Molecular basis of the actions of glycomimetics on keyglycosidases involved in lysosomal storage disorders | 2018 |
| 87 | INFLA-AID | The role of NLRC4 inflammasome in autoinflammatory diseases | 2018 |
| 88 | ZELDA | Investigating the mechanism of spatiotemporal control over genome activation by Zelda in an in vitro reconstituted system | 2019 |
| 89 | GEMZ | Genetic Epilepsy Models in Zebrafish | 2019 |
| 90 | MATHCOV | Maternal temperature history controls progeny vigour | 2018 |
| 91 | MiniBRAIN | Investigating the pathogenic mechanisms underlying TUBB2B-related brain malformations using induced pluripotent stem cells and cerebral organoids. | 2019 |
| 92 | DENOVO-P | De novo Development of Polarity in Plant Cells | 2018 |
| 93 | E-T1IFNs | Elaboration of the type I interferonopathies | 2018 |
| 94 | BSLchlamy | Understanding the essential function of the conserved plant-specific protein phosphatase family BSL | 2018 |
| 95 | SYST-iMYC | Development of an effective and safe systemic Myc inhibitor for the treatment of multiple cancer types. | 2018 |
| 96 | UNBRACE | Investigating the Role of the Unfolded Protein Response as a Novel Targetable Pathway in BRAF Mutant Colorectal Cancer | 2019 |
| 97 | PML-THERAPY | HARNESSING PML NUCLEAR BODIES FOR LEUKAEMIA THERAPY | 2019 |
| 98 | Myel-IN-Crisis | Myelin at the crossroads of Development and Disease | 2018 |
| 99 | VOLARE | Scentsitive nature: Green leaf volatile perception in plants and insects | 2019 |
| 100 | ZebraZoom | ZebraZoom: Kinematic analysis for drug and genetic screening in zebrafish | 2018 |
| 101 | StrepCryptPath | NEW METHOD TO ACTIVATE STREPTOMYCES SECONDARY METABOLISM CRYPTIC PATHWAYS | 2019 |
| 102 | CORKtheCAMBIA | Thickening of plant organs by nested stem cells | 2019 |
| 103 | EngineeringBAP | Engineering brain activity patterns for therapeutics of neuropsychiatric and neurological disorders | 2019 |
| 104 | PATRES-MDS | Pathogenesis and treatment of splicing factor mutant myelodysplastic syndromes | 2019 |
| 105 | IMaP | Imaging tumor vessels as a marker for p53 mutation status in cancer | 2020 |
| 106 | Oncogenic PI3-kinase | New biology of oncogenic PI 3-kinase | 2019 |
| 107 | CheckBacZ | Checkpoints in the bacterial cell cycle: role of the cytokinetic Z-ring and implications for antibiotic resistance | 2020 |
| 108 | XYLAN-2.0 | Plant biomass for high-performing sustainable materials | 2019 |
| 109 | PiQiMosqBite | Understanding the roles of pathogen infection and sensory cue integration in mosquito blood-feeding behavior | 2019 |
| 110 | THyM | Why is Transparent Hypocotyl Mutant showed reduced phototropic response? | 2020 |
| 111 | MechanoMVP | Mechanosensing and Mitral Valve Prolapse: from the Molecular Mechanisms to the Progression of the Disease | 2019 |
| 112 | ABA-GrowthBalance | Growth balance regulation by SnRK1 under ABA-stress conditions | 2019 |
| 113 | SWEETHEART | Shaping fruit morphogenesis of floWEring plants by ElucidaTing HEART-shaped fruit development in Capsella rubella | 2019 |
| 114 | InScope | Integrated analysis of regulatory networks modulating seed coat permeability in natural accessions | 2019 |
| 115 | EPICAN | Inhibiting tumor cell plasticity by targeting the epigenome in breast cancer | 2020 |
| 116 | JS_SCZ | Investigating impact of schizophrenia-associated non-coding variants on enhancer activity using brain organoids | 2020 |
| 117 | RASImmune | Targeting RAS driven tumour immune evasion | 2019 |
| 118 | MitoCRISTAE | Mitochondrial Cristae Biogenesis | 2019 |
| 119 | B-DOMINANCE | B Cell Immunodominance in Antiviral Immunity | 2019 |
| 120 | RNPdynamics | Multivalent interactions driving RNP dynamics in development and disease | 2020 |
| 121 | MicroILCs | "MicroILCs: Deciphering how the gut Microbiota influences Innate Lymphoid Cells in obesity""" | 2021 |
| 122 | Wall-E | Make it, don’t break it: a reconstitution screen for Casparian strip formation in the root endodermis | 2021 |
| 123 | ObeSIK3 | Role of SIK3 in energy homeostasis | 2021 |
| 124 | RASATaC | Regulating RAS Activity to Target RAS-Driven Cancers | 2020 |