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Ultrafast Laplace NMR

Total Cost €


EC-Contrib. €






 UFLNMR project word cloud

Explore the words cloud of the UFLNMR project. It provides you a very rough idea of what is the project "UFLNMR" about.

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Project "UFLNMR" data sheet

The following table provides information about the project.


Organization address
city: OULU
postcode: 90014

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Finland [FI]
 Total cost 2˙625˙000 €
 EC max contribution 2˙625˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-COG
 Funding Scheme ERC-COG
 Starting year 2018
 Duration (year-month-day) from 2018-04-01   to  2023-03-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    OULUN YLIOPISTO FI (OULU) coordinator 2˙625˙000.00


 Project objective

Laplace NMR (LNMR), comprising diffusion and relaxation NMR experiments, provides detailed information on the dynamics and chemical resolution of molecular systems, which is complementary to NMR spectra. Similarly to the traditional NMR spectroscopy, the information content of LNMR can be significantly enhanced by a multidimensional approach. The long experiment time and low sensitivity restrict the applicability of the multidimensional method, however. Based on spatial encoding of multidimensional data, we develop a broad range of single-scan LNMR experiments, constituting a new class of NMR experiments called ultrafast multidimensional LNMR. The method shortens the experiment time by one to three orders of magnitude as compared to the conventional method, offering unprecedented opportunity to study fast processes in real time. Furthermore, it enables boosting the sensitivity by several orders of magnitude by using nuclear spin hyperpolarization, which allows investigation of low-concentration samples. Ultrafast LNMR opens paradigm-breaking prospects in chemical, biochemical, geologic, archaeologic and medical analysis. LNMR can, e.g., provide unique information on the intra- and extracellular metabolic processes, including those of cancer cells, which facilitates diagnostics and helps to find efficient treatments, and it can be exploited in the development of new types of biosensors. Furthermore, the method reveals previously unobservable details about the phase behaviour of ionic liquids, gel and polymer formation, as well as catalysis, which are essential in understanding their performance in technological applications. LNMR is also applicable to portable, single-sided magnets, implying potential to raise the sensitivity of low-field NMR to a completely new level. This entails significant impact on mobile chemical and medical analysis. The low cost of the low-field facility renders advanced NMR analysis broadly available, even in developing countries.


List of deliverables.
Data management plan Open Research Data Pilot 2020-04-09 20:01:26

Take a look to the deliverables list in detail:  detailed list of UFLNMR deliverables.


year authors and title journal last update
List of publications.
2019 Vladimir V. Zhivonitko, Md Sharif Ullah, Ville-Veikko Telkki
Nonlinear sampling in ultrafast Laplace NMR
published pages: 106571, ISSN: 1090-7807, DOI: 10.1016/j.jmr.2019.106571
Journal of Magnetic Resonance 307 2019-12-16
2018 Kristina Sorochkina, Vladimir V. Zhivonitko, Konstantin Chernichenko, Ville-Veikko Telkki, Timo Repo, Igor V. Koptyug
Spontaneous 15 N Nuclear Spin Hyperpolarization in Metal-Free Activation of Parahydrogen by Molecular Tweezers
published pages: 903-907, ISSN: 1948-7185, DOI: 10.1021/acs.jpclett.7b03433
The Journal of Physical Chemistry Letters 9/4 2019-12-16
2019 Muhammad Asadullah Javed, Sanna Komulainen, Hugh Daigle, Boyang Zhang, Juha Vaara, Bing Zhou, Ville-Veikko Telkki
Determination of pore structures and dynamics of fluids in hydrated cements and natural shales by various 1H and 129Xe NMR methods
published pages: 66-74, ISSN: 1387-1811, DOI: 10.1016/j.micromeso.2019.02.034
Microporous and Mesoporous Materials 281 2019-12-16
2019 Petr Štěpánek, Clara Sanchez-Perez, Ville-Veikko Telkki, Vladimir V. Zhivonitko, Anu M. Kantola
High-throughput continuous-flow system for SABRE hyperpolarization
published pages: 8-17, ISSN: 1090-7807, DOI: 10.1016/j.jmr.2019.01.003
Journal of Magnetic Resonance 300 2019-12-16
2018 Guannan Zhang, Susanna Ahola, Mathilde H. Lerche, Ville-Veikko Telkki, Christian Hilty
Identification of Intracellular and Extracellular Metabolites in Cancer Cells Using 13 C Hyperpolarized Ultrafast Laplace NMR
published pages: 11131-11137, ISSN: 0003-2700, DOI: 10.1021/acs.analchem.8b03096
Analytical Chemistry 90/18 2019-12-16
2018 Jared N. King, Alfredo Fallorina, Justin Yu, Guannan Zhang, Ville-Veikko Telkki, Christian Hilty, Tyler Meldrum
Probing molecular dynamics with hyperpolarized ultrafast Laplace NMR using a low-field, single-sided magnet
published pages: 6143-6149, ISSN: 2041-6520, DOI: 10.1039/c8sc01329b
Chemical Science 9/28 2019-12-16
2018 Ville-Veikko Telkki
Hyperpolarized Laplace NMR
published pages: 619-632, ISSN: 0749-1581, DOI: 10.1002/mrc.4722
Magnetic Resonance in Chemistry 56/7 2019-12-16
2019 Pär Håkansson, Muhammad Asadullah Javed, Sanna Komulainen, Linjiang Chen, Daniel Holden, Tom Hasell, Andrew Cooper, Perttu Lantto, Ville-Veikko Telkki
NMR relaxation and modelling study of the dynamics of SF 6 and Xe in porous organic cages
published pages: 24373-24382, ISSN: 1463-9076, DOI: 10.1039/c9cp04379a
Physical Chemistry Chemical Physics 21/44 2019-12-16

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