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NextGen-O2k

Next Generation instrument for in-depth mitochondrial status analyses

Total Cost €

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EC-Contrib. €

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Partnership

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Project "NextGen-O2k" data sheet

The following table provides information about the project.

Coordinator
OROBOROS INSTRUMENTS GmbH 

Organization address
address: SCHOPFSTRASSE 18
city: INNSBRUCK
postcode: 6020
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Austria [AT]
 Project website http://www.oroboros.at
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.2.1.5. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced manufacturing and processing)
2. H2020-EU.2.1.3. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials)
3. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
4. H2020-EU.2.1.2. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2018
 Duration (year-month-day) from 2018-02-01   to  2018-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    OROBOROS INSTRUMENTS GmbH AT (INNSBRUCK) coordinator 50˙000.00

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 Project objective

Mitochondrial dysfunctions are known to be responsible for a number of heterogenous human diseases, such as neurodegenerative disorders, cardiovascular disorders, neurometabolic diseases, cancer, obesity, etc. mitochondria-related research is a growing field, as establishing the mechanisms underlying these disorders is of utmost important for their understanding and treatment. Founded in 1992 in Innsbruck (Austria), Oroboros® produces the gold standard of Oxygraphs, i.e. advanced systems for the study of mitochondrial function, which are sold in 49 countries worldwide and are used by a large scientific network (> 570 labs). With NextGen-O2k project Oroboros® is taking one step further, providing the market with the first all-in-one (i.e. integrated) instrument that allows the simultaneous measurement of several essential parameters involved in mitochondrial functions. As of today, these parameters (such as O2 flux and concentration, membrane potential, Ca2 uptake or reactive oxygen species formation) are measured by different instruments under different conditions. In addition, NextGen-O2k includes a novel Q-redox sensor that has never been exploited before, to accurately study the redox events in the mitochondria. Up to date, Oroboros® counts with 4 prototypes of this new NextGen-O2k product (each of which has different modules in them) which have been tested at laboratory scale. The main goal of NextGen-O2k is thus to finalise the upgrade, integration and validation of all the different modules in a single instrument, so as to be ready for commercialization. In this way, NextGen-O2k will enable a faster screening of mitochondrial dysfunctions and disease by researchers and clinicians. What’s more, this project will also boost the growth of Oroboros® itself, facilitating a 40% increase in personnel and overall revenues of €42 million in 3 years after market launch.

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